Abstract: The present invention relates to a method and compositions for the treatment of age-related macular degeneration (AMD), in particular dry-AMD, specifically geographic atrophy (GA) or advanced dry-AMD. Specifically, the invention relates to an inner-blood-retinal-barrier (iBRB) or blood-brain-barrier (BBB) tight junction protein and/or a circadian clock protein for use in the prevention and/or treatment of age-related macular degeneration.

Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.

Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.

Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.

Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.

Abstract: The present invention relates generally to medical devices containing nanoporous surfaces and methods for making same. More specifically, the invention relates to implantable vascular stents or other biomedical devices having at least one dealloyed nanoporous layer that promotes improved cellular adhesion properties that promote healing and long term biocompatibility. In the case of stents, the nanoporous layer promotes re-endothelialization at sites of stent implantation vasculature, improves overall healing, and reduces inflammation and intimal disease progression. The nanoporous layer may be optionally loaded with one or more therapeutic agent to further improve the function of the implanted stent and further augment clinical efficacy.

Abstract: A baseball fielding glove capable of receiving a human hand is provided. The glove comprises an exterior glove shell and an interior glove liner. The glove comprises a strut in place of traditional webbing. Further, the glove's exterior shell corresponding to the palm of a wearer comprises a plurality of perforations for enhancing ventilation. The fielding glove disclosed is readily adjustable eliminating the need for a breaking-in process. A tensioning cord extending between the strut and finger/thumb stalls of the glove provide an enhanced degree of adjustable characteristics to the glove.

Abstract: The provision of emergency response services to a user can be based on transitioning a communications device associated with a user to a listening mode, setting a first timer, recording user actions with the communications device, ascertaining, based on a status of the first timer and the user actions, whether a criteria with respect to at least user interaction is met, and, if the criteria is met, transitioning the communications device to an emergency communications mode, else resetting the timer and repeating the recording and the ascertaining until the criteria is met. The emergency communication mode consists of forwarding user and live location information to a remote server and receiving emergency contact information, selected based on the user and live location information, for establishing a communication with emergency response personnel.

Abstract: A baseball fielding glove capable of receiving a human hand is provided. The glove comprises an exterior glove shell and an interior glove liner. The glove comprises a strut in place of traditional webbing. Further, the glove's exterior shell corresponding to the palm of a wearer comprises a plurality of perforations for enhancing ventilation. The fielding glove disclosed is readily adjustable eliminating the need for a breaking-in process. A tensioning cord extending between the strut and finger/thumb stalls of the glove provide an enhanced degree of adjustable characteristics to the glove.

Abstract: Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided.

Abstract: A method compensates for changes in drop mass of drops ejected by ink jets in a printhead of an ink jet imaging device. The method includes identifying an average of differences between drop placement position for ink drops on an image receiving member and default ink drop positions. The average of the differences is used to adjust a parameter of one or more ink jet driving signals in response to the average of the differences being greater than a predetermined threshold.

Abstract: Provided herein are isolated nucleic acid molecules representing a genetically defined region of the genome of the aphid resistant soybean plant (Glycine max) cultivar Dowling that confers resistance to soybean aphid (Aphis glycines). Within the region is a gene encoding the aphid resistance protein Rag1. Rag1 aphid resistance amino acid sequences are also provided. Also provided herein are methods for conferring aphid resistance on a plant or enhancing aphid resistance in a plant by transforming it to contain and express such nucleic acid sequences encoding Rag1 aphid resistance or introgressing DNA encoding the trait into the plant by plant breeding. Further provided are polymorphic markers useful for identifying plant germplasm containing aphid resistance, and methods for makings such markers.

Abstract: A method evaluates image quality in an ink printing system and generates data values for altering the operation of the ink printing system. The method includes generating an ink image on an ink image receiving member that corresponds to a digital image stored in the ink printing system, generating a scanned image signal corresponding to the ink image, generating firing signal waveform adjustments and image data adjustments with reference to the scanned image signal corresponding to the ink image, and operating a printhead in an ink imaging system with reference to the firing signal waveform adjustments and the image data adjustments.

Abstract: A method compensates for changes in drop mass of drops ejected by ink jets in a printhead of an ink jet imaging device. The method comprises identifying an average drop placement position for a printhead with reference to ink drop positions on an image receiving member and adjusting a parameter of one or more ink jet driving signals in response to the average drop placement position being greater than a predetermined threshold.

Abstract: A method of compensating for changes in drop mass of drop emitted by at least one ink jet of an ink jet imaging device is provided. The method comprises identifying a drop placement position on an image receiving member of an ink jet imaging device for at least one ink jet of a print head. The identified drop placement position for the at least one ink jet is compared to a default drop placement position for the at least one ink jet to determine a difference in drop placement position. A drive signal for the at least one ink jet is then adjusted in accordance with the difference in drop placement position.

Abstract: An electrical interconnect system includes a first circuit board that includes at least one via, and a conductor configured to transmit an electrical current therethrough. The conductor includes a first signal contact extending from a conductor first end, and a dielectric cylinder configured to receive the conductor therethrough. The dielectric cylinder includes a first bellows element extending from a first end of the dielectric cylinder that is positioned adjacent to the first signal contact. The first bellows element and the dielectric cylinder are configured to form a substantially continuous outer conductor, wherein the conductor and the first bellows are configured to electrically interface to the via and maintain connection thereto using a biasing force.

Abstract: A method evaluates image quality in an ink printing system and generates data values for altering the operation of the ink printing system. The method includes generating an ink image on an ink image receiving member that corresponds to a digital image stored in the ink printing system, generating a scanned image signal corresponding to the ink image, generating firing signal waveform adjustments and image data adjustments with reference to the scanned image signal corresponding to the ink image, and operating a printhead in an ink imaging system with reference to the firing signal waveform adjustments and the image data adjustments.