Patents by Inventor Matthew Ian Heidtman

Matthew Ian Heidtman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alpha (1,2) fucosyltransferase syngenes for use in the production of fucosylated oligosaccharides
    Patent number: 11643675
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: May 9, 2023
    Assignee: Glycosyn LLC
    Inventors: John M. McCoy, Matthew Ian Heidtman, Massimo Merighi
  • Microorganisms and methods for producing sialylated and n-acetylglucosamine-containing oligosaccharides
    Patent number: 11618912
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: April 4, 2023
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy
  • Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides
    Patent number: 11453900
    Abstract: The invention relates to methods and compositions for the production of fucosylated oligosaccharides.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: September 27, 2022
    Assignee: GLYCOSYN LLC
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • SIALYLTRANSFERASES AND USES THEREOF
    Publication number: 20220243237
    Abstract: Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.
    Type: Application
    Filed: March 8, 2022
    Publication date: August 4, 2022
    Inventors: Srikrishnan Mallipeddi, Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • Sialyltransferases and uses thereof
    Patent number: 11274325
    Abstract: Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: March 15, 2022
    Assignee: Glycosyn LLC
    Inventors: Srikrishnan Mallipeddi, Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • ALPHA (1,2) FUCOSYLTRANSFERASE SYNGENES FOR USE IN THE PRODUCTION OF FUCOSYLATED OLIGOSACCHARIDES
    Publication number: 20220056497
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: June 22, 2021
    Publication date: February 24, 2022
    Inventors: John M. McCoy, Matthew Ian Heidtman, Massimo Merighi
  • Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
    Patent number: 11236376
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: February 1, 2022
    Assignee: Glycosyn LLC
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN ENGINEERED BACTERIA
    Publication number: 20210261995
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: April 27, 2021
    Publication date: August 26, 2021
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Alpha (1,2) fucosyltransferase syngenes for use in the production of fucosylated oligosaccharides
    Patent number: 11046984
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: June 29, 2021
    Assignee: Glycosyn LLC
    Inventors: John M. McCoy, Matthew Ian Heidtman, Massimo Merighi
  • Biosynthesis of human milk oligosaccharides in engineered bacteria
    Patent number: 11028419
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: June 8, 2021
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Biosynthesis of human milk oligosaccharides in engineered bacteria
    Patent number: 10815511
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: October 27, 2020
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • MICROORGANISMS AND METHODS FOR PRODUCING SIALYLATED AND N-ACETYLGLUCOSAMINE-CONTAINING OLIGOSACCHARIDES
    Publication number: 20200190548
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: August 28, 2019
    Publication date: June 18, 2020
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy
  • ALPHA (1,2) FUCOSYLTRANSFERASES SUITABLE FOR USE IN THE PRODUCTION OF FUCOSYLATED OLIGOSACCHARIDES
    Publication number: 20200087691
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: April 29, 2019
    Publication date: March 19, 2020
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN ENGINEERED BACTERIA
    Publication number: 20200080119
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 12, 2020
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Biosynthesis of human milk oligosaccharides in engineered bacteria
    Patent number: 10487346
    Abstract: The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: November 26, 2019
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, John M. McCoy, Matthew Ian Heidtman
  • Microorganisms and methods for producing sialylated and N-acetylglucosamine-containing oligosaccharides
    Patent number: 10415069
    Abstract: The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 17, 2019
    Assignee: Glycosyn LLC
    Inventors: Massimo Merighi, Matthew Ian Heidtman, John M. McCoy
  • USE OF PURIFIED 2'-FUCOSYLLACTOSE, 3-FUCOSYLLACTOSE AND LACTODIFUCOTETRAOSE AS PREBIOTICS
    Publication number: 20190255083
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 22, 2019
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • SIALYLTRANSFERASES AND USES THEREOF
    Publication number: 20190218582
    Abstract: Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.
    Type: Application
    Filed: December 14, 2018
    Publication date: July 18, 2019
    Inventors: Srikrishnan Mallipeddi, Matthew Ian Heidtman, Massimo Merighi, John M. McCoy
  • Use of purified 2?-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
    Patent number: 10286001
    Abstract: The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: May 14, 2019
    Assignees: Glycosyn LLC, Trustees of Boston College
    Inventors: David S. Newburg, John M. McCoy, Massimo Merighi, Matthew Ian Heidtman, Zhuoteng Yu
  • Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
    Patent number: 10273516
    Abstract: The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: April 30, 2019
    Assignee: Glycosyn LLC
    Inventors: Matthew Ian Heidtman, Massimo Merighi, John M. McCoy