Patents by Inventor Matthew J. Flynn

Matthew J. Flynn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING DISORDERS WITH ULK INHIBITORS
    Publication number: 20240180923
    Abstract: Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers.
    Type: Application
    Filed: August 29, 2023
    Publication date: June 6, 2024
    Inventors: Rodrigo Ruiz Soto, Frederic J. Reu, Matthew L. Sherman, Daniel L. Flynn, Madhumita Bogdan, Bryan D. Smith, Gada Al-Ani
  • Particle with substituted polyvinyl alcohol coating
    Patent number: 6872696
    Abstract: The present invention provides an improved coating material for use with particles, such as enzyme granules, and the like. In particular, the present invention provides a modified PVA, as well as particles or granules that include such coating. The PVA is modified by substituting hydrophilic moieties for the hydroxyl or alcohol groups of the PVA. Substitution may be achieved with hydrophilic acids, amines, thiols, or combinations thereof.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: March 29, 2005
    Assignee: Genencor International, Inc.
    Inventors: Nathaniel T. Becker, Matthew J. Flynn, Mark S. Gebert
  • Accelerated stability test
    Patent number: 6653093
    Abstract: Enzyme granulates contain besides the enzyme water-soluble and water-insoluble fillers, binders and if required other additives for granulates. In order to stabilize the enzyme, an alkaline or earth alkaline metal formiate is added, as well as reducing sugar, if required. These enzyme granulates may contain all usual enzymes for washing and cleaning purposes, in particular alkaline proteases. A process for preparing these enzyme granulates, as well as their use in powdery washing product compositions are also disclosed.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: November 25, 2003
    Assignee: Genencor International, Inc.
    Inventors: Peter F. Plank, Thomas P Graycar, Matthew J. Flynn
  • Catalase as an oxidative stabilizer in solid particles and granules
    Publication number: 20020147123
    Abstract: The present invention provides a particle containing a peroxide-sensitive component (such as an enzyme; e.g., a hydrolase) and an added catalase component. The particle can be included in a detergent composition with peroxygen bleach.
    Type: Application
    Filed: October 29, 2001
    Publication date: October 10, 2002
    Inventors: Nathaniel T. Becker, Matthew J. Flynn, Mark S. Gebert
  • Particle with substituted polyvinyl alcohol coating
    Publication number: 20020103095
    Abstract: The present invention provides an improved coating material for use with particles, such as enzyme granules, and the like. In particular, the present invention provides a modified PVA, as well as particles or granules that include such coating. The PVA is modified by substituting hydrophilic moieties for the hydroxyl or alcohol groups of the PVA. Substitution may be achieved with hydrophilic acids, amines, thiols, or combinations thereof.
    Type: Application
    Filed: September 12, 2001
    Publication date: August 1, 2002
    Inventors: Nathaniel T. Becker, Matthew J. Flynn, Mark S. Gebert
  • Analgesic dibenz[b,f]oxepins
    Patent number: 4496582
    Abstract: There are described analgesic dibenz[b,f]oxepins having the general formula ##STR1## wherein n is an odd integer 1-7 inclusive; R is --CO.sub.2 R.sub.1 or --CH.sub.2 OR.sub.2 where R.sub.1 is H, C.sub.1-5 lower alkyl, aralkyl, ##STR2## R.sub.3 being C.sub.1-5 lower alkyl; X and Y are each independently hydrogen, halogen, trifluoromethyl, C.sub.1-5 lower alkoxy, C.sub.1-5 lower alkyl, C.sub.1-5 lower alkylthio, or hydroxy; and the dotted line may be a bond or nothing.
    Type: Grant
    Filed: December 12, 1983
    Date of Patent: January 29, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Helen H. Ong, Matthew J. Flynn