Patents by Inventor Matthew J. Hamilton
Matthew J. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240130756Abstract: An articulating surgical instrument includes a housing, a shaft extending distally from the housing, an end effector assembly, and an articulating component interconnecting the shaft and end effector assembly. The articulating component includes a proximal disk connected to the shaft, a distal disk connected to the end effector assembly, an intermediate disk, a first flexible interconnect connecting the proximal and intermediate disks, and a second flexible interconnect connecting the intermediate and distal disks. The first flexible interconnect defines a single plane of bending to enable articulation of the end effector assembly relative to the shaft within a first plane. The second flexible interconnect defines a single plane of bending substantially perpendicular to the single plane of bending of the first flexible interconnect to enable articulation of the end effector assembly relative to the shaft within a second plane substantially perpendicular to the first plane.Type: ApplicationFiled: October 19, 2022Publication date: April 25, 2024Inventors: Matthew S. Cowley, James R. Fagan, Adam J. Neil, Grant J. Hamilton, Jason C. Bledsoe, Nolan H. Howes, Wesley S. Bohn
-
Patent number: 11958849Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.Type: GrantFiled: April 25, 2022Date of Patent: April 16, 2024Assignee: Board of Regents, The University of Texas SystemInventors: Maria Emilia Di Francesco, Philip Jones, Timothy Heffernan, Matthew M. Hamilton, Zhijun Kang, Michael J. Soth, Jason P. Burke, Kang Le, Christopher Lawrence Carroll, Wylie S. Palmer, Richard Lewis, Timothy McAfoos, Barbara Czako, Gang Liu, Jay Theroff, Zachary Herrera, Anne Yau
-
Publication number: 20240050489Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.Type: ApplicationFiled: October 12, 2023Publication date: February 15, 2024Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Matthew J. HAMILTON, Alexander KHORUTS, Michael J. SADOWSKY, Christopher M. STALEY
-
Patent number: 11819523Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.Type: GrantFiled: November 13, 2020Date of Patent: November 21, 2023Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Matthew J. Hamilton, Alexander Khoruts, Michael J. Sadowsky, Christopher M. Staley
-
Patent number: 11801269Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: GrantFiled: June 28, 2022Date of Patent: October 31, 2023Assignee: Regents of the University of MinnesotaInventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Patent number: 11672712Abstract: Systems for providing oncological services to animals are provided. The system includes a transportation vehicle configured to be driven under its own power. The transportation vehicle includes an outer frame housing a plurality of rooms. The plurality of rooms includes an examination room configured to enable a medical professional to medically examine and perform medical diagnostic testing one or more animals, a chemotherapy treatment room configured to enable the medical professional to perform one or more oncological treatments on the one or more animals, and a changing room configured to enable the medical professional to don or doff personal protective equipment.Type: GrantFiled: April 13, 2020Date of Patent: June 13, 2023Assignee: Private Veterinary Oncology Consulting, LLCInventor: Matthew J. Hamilton
-
Publication number: 20230172993Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: ApplicationFiled: August 26, 2022Publication date: June 8, 2023Applicant: Regents of the University of MinnesotaInventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON
-
Publication number: 20220339203Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: ApplicationFiled: June 28, 2022Publication date: October 27, 2022Applicant: Regents of the University of MinnesotaInventors: Michael J. SADOWSKY, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Publication number: 20220110981Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: ApplicationFiled: December 21, 2021Publication date: April 14, 2022Applicant: Regents of the University of MinnesotaInventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON
-
Publication number: 20210315748Abstract: Systems for providing oncological services to animals are provided. The system includes a transportation vehicle configured to be driven under its own power. The transportation vehicle includes an outer frame housing a plurality of rooms. The plurality of rooms includes an examination room configured to enable a medical professional to medically examine and perform medical diagnostic testing one or more animals, a chemotherapy treatment room configured to enable the medical professional to perform one or more oncological treatments on the one or more animals, and a changing room configured to enable the medical professional to don or doff personal protective equipment.Type: ApplicationFiled: April 13, 2020Publication date: October 14, 2021Inventor: Matthew J. Hamilton
-
Publication number: 20210060088Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.Type: ApplicationFiled: November 13, 2020Publication date: March 4, 2021Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Matthew J. HAMILTON, Alexander KHORUTS, Michael J. SADOWSKY, Christopher M. STALEY
-
Patent number: 10849936Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.Type: GrantFiled: July 3, 2017Date of Patent: December 1, 2020Assignee: Regents of the University of MinnesotaInventors: Matthew J. Hamilton, Alexander Khoruts, Michael J. Sadowsky, Christopher M. Staley
-
Publication number: 20190247445Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.Type: ApplicationFiled: July 3, 2017Publication date: August 15, 2019Inventors: Matthew J. HAMILTON, Alexander KHORUTS, Michael J. SADOWSKY, Christopher M. STALEY
-
Patent number: 10286012Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: GrantFiled: May 12, 2017Date of Patent: May 14, 2019Assignee: Regents of the University of MinnesotaInventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Patent number: 10286011Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: GrantFiled: May 12, 2017Date of Patent: May 14, 2019Assignee: Regents of the University of MinnesotaInventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Patent number: 10251914Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: GrantFiled: June 19, 2017Date of Patent: April 9, 2019Assignee: Regents of the University of MinnesotaInventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Patent number: 10028980Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: GrantFiled: June 3, 2016Date of Patent: July 24, 2018Assignee: Regents of the University of MinnesotaInventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Patent number: 9968638Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: GrantFiled: March 9, 2012Date of Patent: May 15, 2018Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTAInventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
-
Publication number: 20180028574Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: ApplicationFiled: June 19, 2017Publication date: February 1, 2018Applicant: Regents of the University of MinnesotaInventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON
-
Publication number: 20180028573Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.Type: ApplicationFiled: June 19, 2017Publication date: February 1, 2018Applicant: Regents of the University of MinnesotaInventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON