Patents by Inventor Matthew J. Hamilton

Matthew J. Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240130756
    Abstract: An articulating surgical instrument includes a housing, a shaft extending distally from the housing, an end effector assembly, and an articulating component interconnecting the shaft and end effector assembly. The articulating component includes a proximal disk connected to the shaft, a distal disk connected to the end effector assembly, an intermediate disk, a first flexible interconnect connecting the proximal and intermediate disks, and a second flexible interconnect connecting the intermediate and distal disks. The first flexible interconnect defines a single plane of bending to enable articulation of the end effector assembly relative to the shaft within a first plane. The second flexible interconnect defines a single plane of bending substantially perpendicular to the single plane of bending of the first flexible interconnect to enable articulation of the end effector assembly relative to the shaft within a second plane substantially perpendicular to the first plane.
    Type: Application
    Filed: October 19, 2022
    Publication date: April 25, 2024
    Inventors: Matthew S. Cowley, James R. Fagan, Adam J. Neil, Grant J. Hamilton, Jason C. Bledsoe, Nolan H. Howes, Wesley S. Bohn
  • Patent number: 11958849
    Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
    Type: Grant
    Filed: April 25, 2022
    Date of Patent: April 16, 2024
    Assignee: Board of Regents, The University of Texas System
    Inventors: Maria Emilia Di Francesco, Philip Jones, Timothy Heffernan, Matthew M. Hamilton, Zhijun Kang, Michael J. Soth, Jason P. Burke, Kang Le, Christopher Lawrence Carroll, Wylie S. Palmer, Richard Lewis, Timothy McAfoos, Barbara Czako, Gang Liu, Jay Theroff, Zachary Herrera, Anne Yau
  • Publication number: 20240050489
    Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.
    Type: Application
    Filed: October 12, 2023
    Publication date: February 15, 2024
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Matthew J. HAMILTON, Alexander KHORUTS, Michael J. SADOWSKY, Christopher M. STALEY
  • Patent number: 11819523
    Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: November 21, 2023
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Matthew J. Hamilton, Alexander Khoruts, Michael J. Sadowsky, Christopher M. Staley
  • Patent number: 11801269
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: October 31, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Patent number: 11672712
    Abstract: Systems for providing oncological services to animals are provided. The system includes a transportation vehicle configured to be driven under its own power. The transportation vehicle includes an outer frame housing a plurality of rooms. The plurality of rooms includes an examination room configured to enable a medical professional to medically examine and perform medical diagnostic testing one or more animals, a chemotherapy treatment room configured to enable the medical professional to perform one or more oncological treatments on the one or more animals, and a changing room configured to enable the medical professional to don or doff personal protective equipment.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: June 13, 2023
    Assignee: Private Veterinary Oncology Consulting, LLC
    Inventor: Matthew J. Hamilton
  • Publication number: 20230172993
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Application
    Filed: August 26, 2022
    Publication date: June 8, 2023
    Applicant: Regents of the University of Minnesota
    Inventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON
  • Publication number: 20220339203
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Application
    Filed: June 28, 2022
    Publication date: October 27, 2022
    Applicant: Regents of the University of Minnesota
    Inventors: Michael J. SADOWSKY, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Publication number: 20220110981
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 14, 2022
    Applicant: Regents of the University of Minnesota
    Inventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON
  • Publication number: 20210315748
    Abstract: Systems for providing oncological services to animals are provided. The system includes a transportation vehicle configured to be driven under its own power. The transportation vehicle includes an outer frame housing a plurality of rooms. The plurality of rooms includes an examination room configured to enable a medical professional to medically examine and perform medical diagnostic testing one or more animals, a chemotherapy treatment room configured to enable the medical professional to perform one or more oncological treatments on the one or more animals, and a changing room configured to enable the medical professional to don or doff personal protective equipment.
    Type: Application
    Filed: April 13, 2020
    Publication date: October 14, 2021
    Inventor: Matthew J. Hamilton
  • Publication number: 20210060088
    Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.
    Type: Application
    Filed: November 13, 2020
    Publication date: March 4, 2021
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Matthew J. HAMILTON, Alexander KHORUTS, Michael J. SADOWSKY, Christopher M. STALEY
  • Patent number: 10849936
    Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.
    Type: Grant
    Filed: July 3, 2017
    Date of Patent: December 1, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Matthew J. Hamilton, Alexander Khoruts, Michael J. Sadowsky, Christopher M. Staley
  • Publication number: 20190247445
    Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.
    Type: Application
    Filed: July 3, 2017
    Publication date: August 15, 2019
    Inventors: Matthew J. HAMILTON, Alexander KHORUTS, Michael J. SADOWSKY, Christopher M. STALEY
  • Patent number: 10286012
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: May 14, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Patent number: 10286011
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: May 14, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Patent number: 10251914
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: April 9, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Patent number: 10028980
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: July 24, 2018
    Assignee: Regents of the University of Minnesota
    Inventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Patent number: 9968638
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: May 15, 2018
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Michael J. Sadowsky, Alexander Khoruts, Alexa R. Weingarden, Matthew J. Hamilton
  • Publication number: 20180028574
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Application
    Filed: June 19, 2017
    Publication date: February 1, 2018
    Applicant: Regents of the University of Minnesota
    Inventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON
  • Publication number: 20180028573
    Abstract: The present invention provides compositions that include an extract of human feces, and methods for using such compositions, including methods for replacing or supplementing or modifying a subject's colon microbiota, and methods for treating a disease, pathological condition, and/or iatrogenic condition of the colon.
    Type: Application
    Filed: June 19, 2017
    Publication date: February 1, 2018
    Applicant: Regents of the University of Minnesota
    Inventors: Michael J. SADOWSKY, Alexander KHORUTS, Alexa R. WEINGARDEN, Matthew J. HAMILTON