Abstract: A dilation assembly comprises an expandable and contractible main body having a corrugated outer surface, a guide cannula configured to be disposed through the main body to guide a movement of the main body, and an anchor configured to fix the main body in a target position.

Abstract: A surgical instrument comprises an end effector configured to core tissue, a handle operatively coupled to the end effector, wherein the handle comprises a trigger to actuate the end effector, the handle comprising a battery dock, the battery dock comprising a protruding member; and a battery unit attachable to the battery dock, wherein the battery unit is in electrical contact with at least one of the handle and the end effector when attached to the battery dock.

Abstract: The present invention is directed to systems, devices and methods for trans-septally delivering carbon dioxide through a minimally invasive catheter to create a gaseous pocket or emphysema between the posterior wall of the left atrium and the esophagus during cardiac ablation of the left atrium. This pocket of gas expanded tissue serves to thermally insulate and separate the esophagus from the left atrium during ablation to prevent the formation of an atrial-esophageal fistula. The system comprises a control system to precisely deliver the gas to a desired location through a needle-based catheter assembly.

Abstract: A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site. A tracking apparatus may be configured to determine a position of a portion of the tissue resection device in three dimensional space.

Abstract: A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Abstract: The present invention is directed to systems, devices and methods for trans-septally delivering carbon dioxide through a minimally invasive catheter to create a gaseous pocket or emphysema between the posterior wall of the left atrium and the esophagus during cardiac ablation of the left atrium. This pocket of gas expanded tissue serves to thermally insulate and separate the esophagus from the left atrium during ablation to prevent the formation of an atrial-esophageal fistula. The system comprises a control system to precisely deliver the gas to a desired location through a needle-based catheter assembly.

Abstract: Systems and methods for sealing tissue sites may comprise coring tissue at a target site such that a tissue core is removed from the target site thereby creating a core cavity at the target site and causing sealing of at least a portion of the target site.

Abstract: A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Abstract: Systems and methods for sealing tissue sites may comprise coring tissue at a target site such that a tissue core is removed from the target site thereby creating a core cavity at the target site and causing sealing of at least a portion of the target site.

Abstract: A method for delivering cancer therapy may comprise introducing a tissue resection device to the tissue site, using the tissue resection device to create a core of tissue, removing at least a portion of the core of tissue from the body to create a tissue cavity, and performing therapeutic management of malignant tissue via the tissue cavity.

Abstract: Systems and methods for sealing tissue sites may comprise coring tissue at a target site such that a tissue core is removed from the target site thereby creating a core cavity at the target site and causing sealing of at least a portion of the target site

Abstract: A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Abstract: A system comprising: a fluid supply configured for the delivery of a fluid; a hollow body in fluid-communication with the fluid supply, the hollow body configured to be disposed between a first biological surface and a second biological surface; and a mechanism configured to control delivery of fluid from the fluid supply and through the hollow body to create separation between the first biological surface and the second biological surface.

Abstract: A system comprising: a fluid supply configured for the delivery of a fluid; a hollow body in fluid-communication with the fluid supply, the hollow body configured to be disposed between a first biological surface and a second biological surface; and a mechanism configured to control delivery of fluid from the fluid supply and through the hollow body to create separation between the first biological surface and the second biological surface.

Abstract: A system comprising: a fluid supply configured for the delivery of a fluid; a hollow body in fluid-communication with the fluid supply, the hollow body configured to be disposed between a first biological surface and a second biological surface; and a mechanism configured to control delivery of fluid from the fluid supply and through the hollow body to create separation between the first biological surface and the second biological surface.

Abstract: A method for navigating a probe to a location within a body of a patient, the method comprising visualizing a three-dimensional image of a region of a body of a patient; receiving a selection of a target location within said three-dimensional image of a region of a patient's body; determining and visualizing a preferred pathway for the probe to follow from an external entry point on the patient's body to the target location; visualizing the preferred pathway for the probe simultaneously with an indication of the current actual position of the probe in real time such that the simultaneous visualizations enables a user to align the current actual position of the probe with the preferred pathway; and updating and visualizing an indication of the current actual position of the probe in real time as the probe is advanced to the target location.

Abstract: A device may comprise a shaft comprising a hollow body, an anchor disposed adjacent an end of the shaft, wherein the anchor is configured to engage a surface to releasably secure the shaft to the surface, and a needle at least partially disposed within the shaft and is configured to be advanced toward the surface and outside of the shaft.

Abstract: An end effector for a surgical clip applier includes an elongate body, a clip revolver rotatably positioned within the body and providing an inner bore that defines a plurality of clip slots angularly spaced from each other about an inner surface of the inner bore, wherein a plurality of surgical clips are receivable within the plurality of clip slots in a nested helical array. First and second jaw members extend past a distal end of the body and aligned to receive a distal-most surgical clip of the plurality of surgical clips, wherein the clip revolver is rotatable to sequentially align each surgical clip with the first and second jaw members.

Abstract: A surgical clip applier includes a drive housing, an elongate shaft that extends distally from the drive housing, an end effector arranged at a distal end of the elongate shaft and including first and second jaw members, and an articulation joint interposing the end effector and the elongate shaft. The articulation joint includes a flexible shaft length articulable in a plane of motion and having a first end and a second end, a lumen defined within the flexible shaft length and extending between the first and second ends, and a clip track provided within the lumen and extending at least partially between the first and second ends to guide surgical clips through the articulation joint.

Abstract: An end effector for a surgical clip applier includes an elongate body, a clip forming system positioned within the body and arranged to receive an unformed surgical clip, and an actuation mechanism operatively coupled to the clip forming system to actuate the clip forming system and thereby bend the unformed surgical clip into a tissue-ready surgical clip. First and second jaw members are positioned at a distal end of the body and arranged to receive the tissue-ready surgical clip for crimping.