Abstract: The present disclosure provides methods and materials for screening a compound or monitoring a subjects response to a compound or dosing regimen for treating frontotemporal dementia (FTD). Methods and materials for identifying and treating a subject having FTD are also provided.

Abstract: A cargo and accessory carrier for attachment to a vehicle receiver hitch includes a riser assembly secured to the vehicle, a door assembly pivotally secured to the riser assembly, and a platform assembly pivotally secured to the door assembly for carrying cargo at a desirable elevation above ground level, such that the door assembly can be pivotally rotated in a horizontal plane and a parallel plane while secured to the riser assembly. The platform assembly can be rotated about the door assembly and maintained in a vertical or horizontal position relative to ground, whether or not it carries a load or it is installed on the vehicle. The carrier provides a multipurpose support assembly which can be used as a "stand alone" unit to carry cargo, and which can be used in combination with other accessory carriers such as a cargo chest, bicycle carrier, ski carrier or any number of other accessory-carrying devices.