Abstract: A transistor device may include a semiconductor structure including a channel layer and a barrier layer on the channel layer, wherein the barrier layer has a higher bandgap than the channel layer; a source contact and a drain contact on the barrier layer; a gate contact on the semiconductor structure between the source contact and the drain contact, the gate contact including a drain-side wing portion extending from a central portion of the gate contact; and a field plate on the semiconductor structure between the gate contact and the drain contact and laterally offset from the gate contact by a distance. The field plate may include a first wing portion extending from a central portion of the field plate.

Abstract: A push notification distribution system centralizes the management and delivery of push notifications to applications executing on electronic devices. Registration requests to register applications for push notifications may be aggregated and sent as an aggregated registration request. The delivery priority of push notifications may be managed according to specified preferences. Upon receiving a push notification intended for an electronic device, a delivery priority of the push notification may be changed if an application identifier associated with the push notification is found on a list of application identifiers with designed delivery priorities.

Abstract: An example operation may include one or more of assigning different criteria to a plurality of nodes of a decision tree model, respectively, iteratively executing the decision tree model on a plurality of training data which causes the plurality of training data to be assigned to the plurality of nodes of the decision tree model based on the different criteria assigned to the plurality of nodes, identifying nodes among the plurality of nodes within the decision tree model which have a purity above a predetermined purity threshold, generating a set of rules based on the identified nodes which have the purity above the predetermined purity threshold, and embedding the set of rules within the decision tree model and storing the decision tree model within a storage device.

Abstract: Techniques for generating a stylized drawing of three-dimensional (3D) shapes using neural networks are disclosed. A processing device generates a set of vector curve paths from a viewpoint of a 3D shape; extracts, using a first neural network of a plurality of neural networks of a machine learning model, surface geometry features of the 3D shape based on geometric properties of surface points of the 3D shape; determines, using a second neural network of the plurality of neural networks of the machine learning model, a set of at least one predicted stroke attribute based on the surface geometry features and a predetermined drawing style; generates, based on the at least one predicted stroke attribute, a set of vector stroke paths corresponding to the set of vector curve paths; and outputs a two-dimensional (2D) stylized stroke drawing of the 3D shape based at least on the set of vector stroke paths.

Abstract: An example operation may include one or more of receiving a loan application of a user, extracting a plurality of personal attributes about the user from the loan application, querying a machine learning model via an application programming interface (API) based on the plurality of attributes about the user to identify one or more rules for auto-adjudicating the loan application, determining whether or not to approve the loan application based on the one or more rules identified via the machine learning model, and transmitting notice of the determination to a device associated with the user.

Abstract: In some embodiments, a head-mounted, near-eye display system comprises a stack of waveguides having integral spacers separating the waveguides. The waveguides may each include diffractive optical elements that are formed simultaneously with the spacers by imprinting. The spacers are disposed on one major surface of each of the waveguides and indentations are provided on an opposite major surface of each of the waveguides. The indentations are sized and positioned to align with the spacers, thereby forming a self-aligned stack of waveguides. Tops of the spacers may be provided with light scattering features, anti-reflective coatings, and/or light absorbing adhesive to prevent light leakage between the waveguides. As seen in a top-down view, the spacers may be elongated along the same axis as the diffractive optical elements. The waveguides may include structures (e.g.

Abstract: This disclosure provides methods, components, devices and systems for wireless communications. Some aspects more specifically relate to elevation estimation for determining operating channels and transmission parameters. A wireless communication device, such as a cloud service, may receive geolocation information of an access point (AP). Additionally, or alternatively, the wireless communication device may receive air pressure and temperature information of the AP. Using the geolocation information and building datasets including locations and heights of buildings surrounding the AP, the wireless communication device may identify a highest building and based on its, height estimate an elevation of the AP. Based on the estimated building height and elevation, the wireless communication device may determine a set of transmission parameters for the AP and transmit an indication of the set to the AP.

Abstract: Methods, systems, and devices for leveraging data already collected on a user in a secure and private manner, in particular to verify user credentials for third parties. The methods, systems, and devices innovate beyond traditional security and privacy platforms in computer systems by processing the data to create a useable metric for the purposes of the third parties, in which the useable metric preserves the security and privacy of the underlying data.

Abstract: Provided herein are anti-CCR8 antibodies or antigen binding fragment thereof, which bind to CCR8, wherein the CCR8 is a human CCR8 and the antibody does not bind human CCR4. The anti-CCR8 antibodies or antigen binding fragment of the disclosure are useful for the treatment of cancer diseases through the elimination of regulatory T cells. Also provided herein are methods of use for the anti-CCR8 antibodies or antigen binding fragment thereof.

Abstract: Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders.

Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.

Abstract: A surgical instrument is disclosed herein. The surgical instrument can include an end effector that includes jaws configured to transition between an opened condition and a closed condition, a plurality of electrodes positioned within the jaws of the end effector, a control circuit, and a memory configured to store an algorithm configured to cause the control circuit to determine an impedance signal based on signals received from the plurality of electrodes, detect a media positioned between the jaws of the end effector based on the determined impedance signal, determine a position of the detected media based on the received signals, and generate an alert associated with the detected media and the determined position.

Abstract: Provided herein are anti-EGFRvII antibodies and binding fragments thereof. The anti-EGFRvIII antibodies of the disclosure are useful for the treatment of cancers through, e.g., antibody-dependent cell cytotoxicity (ADCC). Also provided herein are methods of making and using the anti-EGFRvIII antibodies for the treatment of cancer, and polynucleotides that encode the same.

Abstract: Provided for herein is a method of cell transplantation using an injection attachment having a hub containing a plurality of cells and a cannula extending from a distal end of the hub. The method includes orienting the injection attachment such that the cannula points downwardly until the plurality of cells settle together proximate the distal end, inserting the cannula into a tissue of a subject, and injecting the volume of cells into the tissue of the subject using the injection attachment.

Abstract: A system includes a dynamic compressor and a controller having a processor and a memory. The compressor includes a first compressor stage having a first variable inlet guide vane (VIGV) and a second compressor stage having a second VIGV. The memory stores instructions that program the processor to operate the compressor at a current speed, a first position of the first VIGV, and a second position of the second VIGV to compress the working fluid, and to determine if a condition is satisfied. If the condition is not satisfied, the processor is programmed to continue to operate the compressor at the current speed, the first position of the first VIGV, and the second position of the second VIGV. If the condition is satisfied, the processor is programmed to change the second position of the second VIGV to a third position and maintain the first position of the first VIGV.

Abstract: A contact lens comprising one or more microchannels for transport of liquid through the lens is provided. The contact lens can be made by contacting a curable composition with a microfiber that is insoluble in the curable composition; curing the curable composition to provide a polymeric lens body with the microfiber embedded therein; and contacting the polymeric lens body with a solvent to dissolve the microfiber.

Abstract: A gaming system includes a game controller configured to, for each game round of a game: select symbols from a first set that includes first special symbols for display in symbol positions associated with reels to form a game outcome; select a second special symbol from a second set and associate the selected second special symbol with an initial reel; associate each previously selected second special symbol with a subsequent reel or remove a previously selected second special symbol; evaluate the game outcome to determine any winning symbol combination occurring in the game outcome; for each reel, accumulate any first special symbol occurring in the game outcome and determine a prize value based on the accumulated first special symbols and any second special symbol associated with the reel when an accumulation threshold for the reel is met; and generate an award based on a total of prize values.

Abstract: Systems and methods for providing a separate interest rate for an individual transaction are disclosed. A system may provide a service associated with a account having an account balance and an associated first interest rate. The system may include a service device having one or more memory devices storing instructions and one or more processors configured to execute the instructions to perform a separate interest rate service process. The process may include providing a separate interest rate service offer to a client device and receiving a separate interest rate selection from the client device. The process may also include determining a selected portion of the account balance corresponding to an amount to which a second interest rate, different from the first interest rate, is to be applied based on the separate interest rate selection.

Abstract: Described herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, such as cancer, metabolic and blood disorders. Compounds of Formula (I) have the following structure of Formula (I).

Abstract: A method for analyzing one or more conditions of a transportation pathway includes obtaining, using an imaging device of an inspection system, image data reproducible as a plurality of images of the transportation pathway, each of the plurality of images being reproducible as an image of a portion of the transportation pathway, each portion of the transportation pathway having an associated location along a length of the transportation pathway, analyzing, using one or more processors of the inspection system, the image data to determine a first plurality of metrics indicative of a condition of the transportation pathway at each of the associated locations, and generating a first graph, using the determined first plurality of metrics, that is indicative of the condition of the transportation pathway at each of the associated locations.