Abstract: Metadata structures and related locking techniques to improve performance and scalability in a cluster file system are disclosed. In one implementation, a method includes receiving, by a server, a request for a first file, retrieving, by the server, the first file and metadata for a second file that is related to the first file, and sending, by the server in response to the retrieving and in advance of any request for the metadata for the second file, an asynchronous lock request to obtain a lock for accessing at least a portion of the metadata for the second file.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Metadata structures and related locking techniques to improve performance and scalability in a cluster file system are disclosed. In one implementation, a method includes receiving, by a server, a request for a first file, retrieving, by the server, the first file and metadata for a second file that is related to the first file, and sending, by the server in response to the retrieving and in advance of any request for the metadata for the second file, an asynchronous lock request to obtain a lock for accessing at least a portion of the metadata for the second file.

Abstract: A cluster file system is disclosed. A plurality of disk servers, operating as a single distributed disk server layer, are connected to the one or more physical disks. Each disk server stores metadata for each of the files. A plurality of lock servers, having one or more locks for each file and associated file system metadata operates as a single centralized distributed lock server to coordinate access to the files stored by the disk server layer. A plurality of asynchronous file servers, operating as a single distributed file server layer in response to a request for a file from a user program: (i) retrieves the requested file from the disk server layer and at least one lock, associated with the retrieved file, from the lock server, and (ii) retrieves metadata for at least one file that is related to the requested files, and at least one lock, for each file that has had its metadata retrieved.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: A cluster file system is disclosed. A plurality of disk servers, operating as a single distributed disk server layer, are connected to the one or more physical disks. Each disk server stores metadata for each of the files. A plurality of lock servers, having one or more locks for each file and associated file system metadata operates as a single centralized distributed lock server to coordinate access to the files stored by the disk server layer. A plurality of asynchronous file servers, operating as a single distributed file server layer in response to a request for a file from a user program: (i) retrieves the requested file from the disk server layer and at least one lock, associated with the retrieved file, from the lock server, and (ii) retrieves metadata for at least one file that is related to the requested files, and at least one lock, for each file that has had its metadata retrieved.

Abstract: A cluster file system is disclosed. A plurality of disk servers, operating as a single distributed disk server layer, are connected to the one or more physical disks. Each disk server stores metadata for each of the files. A plurality of lock servers, having one or more locks for each file and associated file system metadata operates as a single centralized distributed lock server to coordinate access to the files stored by the disk server layer. A plurality of asynchronous file servers, operating as a single distributed file server layer in response to a request for a file from a user program: (i) retrieves the requested file from the disk server layer and at least one lock, associated with the retrieved file, from the lock server, and (ii) retrieves metadata for at least one file that is related to the requested files, and at least one lock, for each file that has had its metadata retrieved.

Abstract: A distributed file system is disclosed. A plurality of disk servers, operating as a single distributed disk server layer, are connected to the one or more physical disks. Each disk server stores meta-data for each of the files. A plurality of lock servers, having one or more locks for each file operates as a single distributed lock server to coordinate access to the files stored by the disk server layer. A plurality of asynchronous file servers, operating as a single distributed file server layer in response to a request for a file from a user program: (i) retrieves the requested file from the disk server layer and at least one lock, associated with the retrieved file, from the lock server, and (ii) retrieves meta-data for at least one file that is related to the requested files, and at least one lock, for each file that has had its meta-data retrieved.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: A cerium-based coating for corrosion resistance is applied by exposing a cleaned aluminum-based component to a corrosion-inhibiting cerium solution containing cerium ions in the presence of an oxidizing agent. The coating deposits spontaneously without an external source of electrons.

Abstract: A III-V field effect transistor comprising a semiconductor channel layer having an electrically conducting channel; an ohmic contact layer on the semiconductor channel layer, the ohmic contact layer having a recess structure disposed therethrough to the semiconductor channel layer; the bottom of the ohmic contact layer comprising an etch stop layer comprising Aluminium and Phosphorous and defining the shape of the recess at its junction with the semiconductor channel layer.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: A cerium-based coating for corrosion resistance is applied by exposing a cleaned aluminum-based component to a corrosion-inhibiting cerium solution containing cerium ions in the presence of an oxidizing agent. The coating deposits spontaneously without an external source of electrons.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.

Abstract: Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.