Patents by Inventor Matthew Rust
Matthew Rust has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9144648Abstract: An injector for injecting medicament in a patient. The injector includes a container comprising a fluid chamber containing a first volume of a medicament, and an injection conduit associated with the fluid chamber for defining a fluid pathway therefrom to inject the medicament from the fluid chamber through the injection conduit to an injection location. The injector also includes a firing mechanism associated with the fluid chamber for expelling the medicament from the fluid chamber through the injection conduit, and a volume-control mechanism operable to control a fraction of the first volume of medicament that is injected when the firing mechanism is actuated to inject the medicament.Type: GrantFiled: May 2, 2007Date of Patent: September 29, 2015Assignee: ANTARES PHARMA, INC.Inventors: Paul R. Lesch, Jr., Matthew Rust, Tom KraMer
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Patent number: 8986375Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.Type: GrantFiled: March 12, 2013Date of Patent: March 24, 2015Assignee: Medtronic, Inc.Inventors: Kshitija Garde, Philip Haarstad, Igor Kovalsky, Stephen Nash, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Jeffrey Sandstrom, Padraig Savage, William Steinberg
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Patent number: 8986372Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.Type: GrantFiled: August 19, 2013Date of Patent: March 24, 2015Assignee: Medtronic, Inc.Inventors: Robert Murry, III, Susheel Deshmukh, Padraig Savage, Matthew Rust
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Patent number: 8915889Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.Type: GrantFiled: January 30, 2013Date of Patent: December 23, 2014Assignee: Antares Pharma, Inc.Inventors: Janice L. Cox, Matthew Rust, Thomas E. KraMer, Peter Hoeft
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Publication number: 20140330368Abstract: A system includes a medical device for implanting in a valve of a subject, the implantable medical device having a self-expanding frame; and a holder configured to retain the frame of the implantable medical device in a constricted configuration and to control expansion of the frame. The holder has a controllably constrictable and expandable loop, wherein the loop is disposed about at least a portion of the self-expanding frame such that constriction or expansion of the first loop controls constriction or expansion of the frame.Type: ApplicationFiled: May 2, 2014Publication date: November 6, 2014Applicant: Medtronic, Inc.Inventors: Michael Gloss, Timothy Groen, Carolyn Majkrzak, Behrooz Nadian, Matthew Rust, Timothy Ryan, Matthew Weston, Marc Anderson, Evelyn Birmingham, Mark Casley, Deirdre McGowan Smyth
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Publication number: 20140330372Abstract: A device, such as a prosthetic heart valve, for implantation in a patient's valve, having one or more visible markings configured to be aligned with one or more anatomical structures of the patient's valve, such as an annulus or a commissure. The markings facilitating accurate implantation of the device at a proper depth or in a proper orientation.Type: ApplicationFiled: May 2, 2014Publication date: November 6, 2014Applicant: Medtronic, Inc.Inventors: Matthew W. Weston, Stella H. Kim, Carolyn C. Majkrzak, Michael Gloss, Timothy Groen, Behrooz Nadian, Matthew Rust, Timothy Ryan
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Publication number: 20140330371Abstract: A valve prosthesis includes an expandable frame comprising an outflow portion and an inflow portion connected to the outflow portion. The frame defines a central lumen extending between the outflow portion and the inflow portion. The frame is generally cylindrical in a fully expanded configuration. When the frame is in the fully expanded configuration, an outer surface of the inflow portion is concave. The inflow portion has an upper inflow portion and a lower inflow portion. When the frame is in the fully expanded configuration, the upper inflow portion flares outwardly from the central lumen of the frame to greater extent than the lower inflow portion.Type: ApplicationFiled: May 2, 2014Publication date: November 6, 2014Applicant: Medtronic, Inc.Inventors: Michael Gloss, Timothy Groen, Carolyn Majkrzak, Matthew Rust, Timothy Ryan, Matthew Weston
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Patent number: 8876883Abstract: A stent graft includes a stent graft material of tubular shape and annular shaped stent elements coupled to the stent graft material. The stent graft further includes hooked fixation elements, having hook-end portions and coupling-end, circumferentially spaced about an annular shaped spring attachment element, and coupled to the stent graft at apexes of the spring attachment element. Before deployment the hook-end portions of the apexes of the attachment element and the hooked fixation elements attached thereto are compressed within the space bounded by the interior and exterior sides of the spring attachment element and angled laser cut strut inner surfaces under each apex of the spring attachment element are cut at an angle to cause apex and hook rotation at expansion and deployment.Type: GrantFiled: April 24, 2009Date of Patent: November 4, 2014Assignee: Medtronic Vascular, Inc.Inventor: Matthew Rust
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Publication number: 20140277419Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.Type: ApplicationFiled: March 12, 2013Publication date: September 18, 2014Applicant: MEDTRONIC, INC.Inventors: Kshitija Garde, Philip Haarstad, Igor Kovalsky, Stephen Nash, Michael Krivoruchko, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Jeffrey Sandstrom, Padraig Savage, Adam Shipley, William Steinberg
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Patent number: 8828074Abstract: A stent-graft includes a short tube graft and patch located inside of a primary graft. The patch forms a smooth and reliably sealed transition between the primary graft and the short tube graft. Accordingly, the disruption to fluid, e.g., blood, flowing through the lumen of the primary graft by the short tube graft is minimal. Further, the patch supports the inner end of the short tube graft. Thus, the patch, the short tube graft and the primary graft form a stable three-dimensional structure.Type: GrantFiled: April 21, 2006Date of Patent: September 9, 2014Assignee: Medtronic Vascular, Inc.Inventors: Jia Hua Xiao, Matthew Rust
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Patent number: 8771344Abstract: A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.Type: GrantFiled: August 15, 2013Date of Patent: July 8, 2014Assignee: Medtronic, Inc.Inventors: Don Tran, Nathan Wiemeyer, Susheel Deshmukh, Leonel Mendoza, Matthew Rust
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Publication number: 20140135909Abstract: The delivery systems disclosed herein can create simultaneous movement of an inner and an outer sheath of the delivery system. The delivery systems can generally include a handle assembly and a delivery catheter. In certain embodiments, the inner shaft and the outer sheath can be slidably controlled by a control element in the handle. The handle assembly can include a housing with a thumbwheel acting as the control element. In certain embodiments, movement of the inner shaft and the outer sheath can be caused via a gear-type system. In certain embodiments, the handle assembly can include a rotatable housing. A control element can rotate the housing, which can cause a first boss associated with the outer sheath and a second boss associated with the inner shaft to move in opposite directions.Type: ApplicationFiled: November 14, 2012Publication date: May 15, 2014Applicant: MEDTRONIC VASCULAR GALWAY LIMITEDInventors: Damian Carr, Kate Corish, Niall Duffy, Ronan Rogers, Yossi Tuval, Frank White, Declan Costello, John Gallagher, James Kearns, Edmond Sheahan, Matthew Rust
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Patent number: 8715336Abstract: A stent graft includes at least one aperture extending through the main body thereof, into which an extension portion may be deployed for positioning within an adjacent branch flow lumen. The extension portions include self biasing features, wherein the extension is biased into engagement with the main body to seal the interface thereof. Additionally, the extension portion may be configured for tortuous or deviated anatomy, to enable sealing of the extension portion with the body while extending the extension portion in a substantially non-radial direction from the main body.Type: GrantFiled: April 19, 2007Date of Patent: May 6, 2014Assignee: Medtronic Vascular, Inc.Inventors: Jack Chu, David R. Erickson, Jonathon Morris, Prema Ganesan, Curtis Hanson, Matthew Rust, Charles Thomas, James Machek
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Publication number: 20140100653Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.Type: ApplicationFiled: December 9, 2013Publication date: April 10, 2014Applicant: Medtronic Corevalve LLCInventors: Padraig SAVAGE, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Michael Krivoruchko
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Publication number: 20140012369Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.Type: ApplicationFiled: August 19, 2013Publication date: January 9, 2014Applicant: Medtronic, Inc.Inventors: Robert Murry, III, Susheel Deshmukh, Padraig Savage, Matthew Rust
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Patent number: 8623079Abstract: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.Type: GrantFiled: April 25, 2011Date of Patent: January 7, 2014Assignee: Medtronic, Inc.Inventors: Padraig Savage, Gianfranco Pellegrini, Finn Rinne, Matthew Rust, Michael Krivoruchko
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Publication number: 20140005769Abstract: A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.Type: ApplicationFiled: August 15, 2013Publication date: January 2, 2014Applicant: Medtronic, Inc.Inventors: Don Tran, Nathan Wiemeyer, Susheel Deshmukh, Leonal Mendoza, Matthew Rust
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Patent number: 8512401Abstract: A delivery device for percutaneously deploying a stented prosthetic heart valve. The device includes a delivery capsule and a recapture sheath. The capsule is configured to compressively retain the prosthesis. The recapture sheath includes a funnel segment having a plurality of circumferentially spaced runners and a polymer overlay. The runners are attached to a shaft and terminate at a distal tip. The overlay surrounds the runners, and is bonded to the shaft but not to at least the tips. The funnel segment is transitionable from a normal condition to an expanded condition forming a funnel shape with a distally increasing diameter, and self-transitionable back toward the normal condition. The funnel segment facilitates sliding of the capsule over a partially deployed region of the prosthesis as part of a recapturing operation. The runners provide columnar strength, with the overlay controlling a shape of the funnel segment.Type: GrantFiled: April 12, 2010Date of Patent: August 20, 2013Assignee: Medtronic, Inc.Inventors: Robert Murray, III, Susheel Deshmukh, Padraig Savage, Matthew Rust
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Patent number: 8512400Abstract: A device for percutaneously repairing a heart valve of a patient including a self-expanding, stented prosthetic heart valve and a delivery system. The delivery system includes delivery sheath slidably receiving an inner shaft forming a coupling structure. A capsule of the delivery sheath includes a distal segment and a proximal segment. An outer diameter of the distal segment is greater than that of the proximal segment. An area moment of inertia of the distal segment can be greater than an area moment of inertia of the proximal segment. Regardless, an axial length of the distal segment is less than the axial length of the prosthesis. In a loaded state, the prosthesis engages the coupling structure and is compressively retained within the capsule. The capsule is unlikely to kink when traversing the patient's vasculature, such as when tracking around the aortic arch, promoting recapturing of the prosthesis.Type: GrantFiled: April 9, 2010Date of Patent: August 20, 2013Assignee: Medtronic, Inc.Inventors: Don Tran, Nathan Wiemeyer, Susheel Deshmukh, Leonal Mendoza, Matthew Rust
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Patent number: 8376993Abstract: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.Type: GrantFiled: August 5, 2009Date of Patent: February 19, 2013Assignee: Antares Pharma, Inc.Inventors: Janice L. Cox, Matthew Rust, Thomas E. KraMer, Peter Hoeft