Patents by Inventor Matthew S Alexander

Matthew S Alexander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 4-aminoisoindoline-1,3-dione compounds, compositions thereof, and methods of treatment therewith
    Patent number: 11945804
    Abstract: Provided herein are 4-aminoisoindoline-1,3-dione compounds having the following structure: wherein R, Ring A, and n are as defined herein, compositions comprising an effective amount of a 4-aminoisoindoline-1,3-dione compound, and methods for treating or preventing disorders.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: April 2, 2024
    Assignee: Celgene Corporation
    Inventors: Matthew D. Alexander, Soraya Carrancio, Matthew D. Correa, Virginia Heather Sharron Grant, Joshua Hansen, Roy L. Harris, Dehua Huang, Timothy S. Kercher, Antonia Lopez-Girona, Mark A. Nagy, Veronique Plantevin-Krenitsky
  • COMPOUNDS AND METHODS FOR THE TREATMENT OF AUTISM SPECTRUM DISORDER AND OTHER NEUROLOGICAL OR PSYCHIATRIC DISORDERS
    Publication number: 20210236438
    Abstract: Disclosed are methods of treating autism spectrum disorder (ASD) by administering a therapeutically effective amount of an isoprenoid antibiotic. Also disclosed are methods of modulating (either upregulation or downregulation) hnRNP L and hnRNP L targets by administering a therapeutically effective amount of an isoprenoid antibiotic. Methods of screening compounds for use in treating autism spectrum disorder (ASD) are also described.
    Type: Application
    Filed: June 5, 2019
    Publication date: August 5, 2021
    Inventors: Isabelle Draper, Alan S. Kopin, Matthew S. Alexander, Louis M. Kunkel
  • Compounds and methods for the treatment of muscular disease, and related screening methods
    Patent number: 9662314
    Abstract: Disclosed are methods of treating a muscle disease and improving normal muscle function by administering a therapeutically effective amount of an isoprenoid antibiotic. Also disclosed are methods of upregulating hnRNP L and hnRNP L targets by administering a therapeutically effective amount of an isoprenoid antibiotic. Methods of screening compounds for use in treating muscle disease and improving muscle function are also described.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: May 30, 2017
    Assignees: Tufts Medical Center, Inc., Children's Medical Center Corporation
    Inventors: Isabelle Draper, Louis M. Kunkel, Matthew S. Alexander, Alan S. Kopin
  • Electrostatic spraying device and a method of electrostatic spraying
    Patent number: 9211551
    Abstract: An electrostatic spraying device (1) and method for dispensing a controlled volume of liquid in pulses using an emitter (2) having a spray area (29) from which the liquid can be sprayed, a means for injecting charges into the liquid, whereby, in use, the liquid (3) is delivered to the spray area by electrostatic forces and electrostatic spraying occurs in one or more pulses whilst the charges are injected. The charges may be injected by a time-varying or constant non-zero electric field so that electrospray occurs above a threshold value.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: December 15, 2015
    Assignee: Queen Mary & Westfield College
    Inventors: John P. W. Stark, Matthew S. Alexander, Mark D. Paine, Kate L. Smith
  • Electrospray device and a method of electrospraying
    Patent number: 8840037
    Abstract: An electrospray apparatus for dispensing a controlled volume of liquid in pulses at a constant frequency is provided. The apparatus comprises an emitter (70) having a spray area from which liquid can be sprayed, a means for applying an electric field (78) to liquid in, on or adjacent to the emitter (70). In use, liquid is drawn to the spray area by electrostatic forces and electrospray occurs in pulses at a constant frequency whilst the electric field (78) is applied.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: September 23, 2014
    Assignee: Queen Mary & Westfield College
    Inventors: John P W Stark, Mark D Paine, Matthew S Alexander
  • Compositions and Methods for the Treatment of Muscular Disease, and Related Screening Methods
    Publication number: 20140243378
    Abstract: Disclosed are methods of treating a muscle disease and improving normal muscle function by administering a therapeutically effective amount of an isoprenoid antibiotic. Also disclosed are methods of upregulating hnRNP L and hnRNP L targets by administering a therapeutically effective amount of an isoprenoid antibiotic. Methods of screening compounds for use in treating muscle disease and improving muscle function are also described.
    Type: Application
    Filed: October 19, 2012
    Publication date: August 28, 2014
    Applicants: Tufts Medical Center, Inc., Children's Medical Center Corporation
    Inventors: Isabelle Draper, Louis M. Kunkel, Matthew S. Alexander, Alan S. Kopin
  • ELECTROSTATIC SPRAYING DEVICE AND A METHOD OF ELECTROSTATIC SPRAYING
    Publication number: 20100155496
    Abstract: An electrostatic spraying device (1) and method for dispensing a controlled volume of liquid in pulses using an emitter (2) having a spray area (29) from which the liquid can be sprayed, a means for injecting charges into the liquid, whereby, in use, the liquid (3) is delivered to the spray area by electrostatic forces and electrostatic spraying occurs in one or more pulses whilst the charges are injected. The charges may be injected by a time-varying or constant non-zero electric field so that electrospray occurs above a threshold value.
    Type: Application
    Filed: May 19, 2008
    Publication date: June 24, 2010
    Applicant: Queen Mary & Westfield College
    Inventors: John P. W. Stark, Matthew S. Alexander, Mark D. Paine, Kate L. Smith
  • Electrospray Device And A Method of Electrospraying
    Publication number: 20090152371
    Abstract: An electrospray apparatus for dispensing a controlled volume of liquid in pulses at a constant frequency is provided. The apparatus comprises an emitter (70) having a spray area from which liquid can be sprayed, a means for applying an electric field (78) to liquid in, on or adjacent to the emitter (70). In use, liquid is drawn to the spray area by electrostatic forces and electrospray occurs in pulses at a constant frequency whilst the electric field (78) is applied.
    Type: Application
    Filed: December 7, 2006
    Publication date: June 18, 2009
    Applicant: QUEEN MARY & WESTFIELD COLLEGE
    Inventors: John P W Stark, Mark D Paine, Matthew S Alexander