Abstract: Compositions for treating or controlling infections comprise a fluoroquinolone having Formulae I-VIII and have a pH in the range from about 3.5 to about 5.5 or from about 10.5 to about 12. Methods for treating or controlling such infection use such compositions. Such compositions and methods can deliver a higher amount of the fluoroquinolone to the affected site.

Abstract: Compositions for modulating endophthalmitis comprise a fluoroquinolone having one of Formulae I-VIII. Methods for modulating endophthalmitis comprise administering such compositions to a subject in need thereof. The compositions and methods are suitable for modulating post-operative endophthalmitis, post-traumatic endophthalmitis, non-infectious endophthalmitis, panophthalmitis, hematogenous endophthalmitis, or combinations thereof.

Abstract: Compositions for treating or controlling infections comprise a fluoroquinolone having Formulae I-VIII and have a pH in the range from about 3.5 to about 5.5 or from about 10.5 to about 12. Methods for treating or controlling such infection use such compositions. Such compositions and methods can deliver a higher amount of the fluoroquinolone to the affected site.

Abstract: Compositions for modulating endophthalmitis comprise a fluoroquinolone having one of Formulae I-VIII. Methods for modulating endophthalmitis comprise administering such compositions to a subject in need thereof. The compositions and methods are suitable for modulating post-operative endophthalmitis, post-traumatic endophthalmitis, non-infectious endophthalmitis, panophthalmitis, hematogenous endophthalmitis, or combinations thereof.

Abstract: Compositions for treating, reducing, ameliorating, or preventing infection of an ear or upper respiratory tract comprise a fluroquinolone having Formula I, II, or III. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against certain antibiotic-resistant microbial pathogens found in such infection.

Abstract: An ophthalmic treatment system comprises an ophthalmic treatment solution and a biguanide antimicrobial agent in solid form and in contact with said treatment solution such as to inhibit bacterial and/or fungal growth in said solution. The biguanide is partially or wholly terminated with an amine compound.

Abstract: This invention relates to compositions comprising pheniramine. In particular, it has been found that pheniramine in combination with n effective amount of a povidone provides improved comfort and reduces the symptoms of dryness compared to compositions with pheniramine alone.

Abstract: An oil-in-water emulsion for treating the skin comprising from about 2 to about 10 weight percent of a cationic emulsifier such as dimethyl distearyl ammonium halide, a substantially nonionizable humectant such as glycerine and a weakly acidic material having a disassociation constant of about I to 6. The amount of weakly acidic material is such that the pH of the finished emulsion is about 2.5 to 4.5. also disclosed is a method of preparing the emulsion.

Abstract: A oil-in-water emulsion for treating the skin comprising from about 2 to about 10 weight percent of a cationic emulsifier such as dimethyl distearyl ammonium halide, a substantially nonionizable humectant such as glycerine and a weakly acidic material having a disassociation constant of about 1 to 6. The amount of weakly acidic material is such that the pH of the finished emulsion is about 2.5 to 4.5. Also disclosed is a method of preparing the emulsion.

Abstract: The present invention is directed to a method of forming an oil-in-water emulsion containing water-insoluble components, a water-soluble humectant, a weakly acidic component such as an alpha-hydroxy acid and a quaternary ammonium cationic emulsifier. The emulsion is used as a stable skin care cream.

Abstract: A method of treating contact lenses comprising the use of an iodine-chromophore to indicate neutralization of oxidative disinfectants.

Abstract: A composition and method for cleaning and disinfecting of contact lenses that employ an electrical field applied to a lens that causes contaminating deposits to migrate therefrom is described. The composition of the invention includes a pair of component materials having different electrochemical potentials wherein the materials are substantially contained in a form wherein each material remains sufficiently physically separated when in contact with opposite sides of the lens such that the difference in electrochemical potential between the two materials is sufficient to cause charged contaminating deposits to migrate from the lens. The method of the invention requires placing a contaminated lens between a pair of component materials having different electrochemical potentials wherein physical separation is maintained, preferably, by including one of the components in a gel while the other component is in solution or another gel.