Patents by Inventor Matthew T. Wolf

Matthew T. Wolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDUCTION OF ANTI-TUMORAL IMMUNE MICROENVIRONMENTS
    Publication number: 20210236694
    Abstract: Implanted extracellular matrix scaffolds used for regenerative medicine generate a highly activated and unique immune response that inhibits tumor formation by T helper cell-macrophage interactions.
    Type: Application
    Filed: May 3, 2018
    Publication date: August 5, 2021
    Inventors: Jennifer H. Elisseeff, Matthew T. Wolf
  • Extracellular matrix mesh coating
    Patent number: 10286119
    Abstract: Provided are surgical meshes embedded in a gelled, solubilized extracellular matrix (ECM) composition, methods of making the same, and methods of using the same to repair defects in a body. The surgical mesh may be a synthetic polymer such as polypropylene, and the ECM coating reduces the foreign body response and scarring at the site of implantation. The device is useful for repairing hernias, pelvic floor disorders, and in breast reconstructions.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: May 14, 2019
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Matthew T. Wolf
  • Bi-Layer Extra Cellular Matrix Scaffolds and Uses Therefor
    Publication number: 20180243473
    Abstract: Provided herein is a bilayer medical device (e.g., “patch”) for use in treating ischemic cardiomyopathy as well as for treatment of other conditions. The medical device comprises a first, support layer and a second, ECM-containing layer over the first layer. Methods of making and using the device also are provided herein.
    Type: Application
    Filed: September 9, 2016
    Publication date: August 30, 2018
    Inventors: Stephen F. Badylak, Antonio D'Amore, Matthew T. Wolf, William R. Wagner
  • Extracellular Matrix Mesh Coating
    Publication number: 20150297798
    Abstract: Provided are surgical meshes embedded in a gelled, solubilized extracellular matrix (ECM) composition, methods of making the same, and methods of using the same to repair defects in a body. The surgical mesh may be a synthetic polymer such as polypropylene, and the ECM coating reduces the foreign body response and scarring at the site of implantation. The device is useful for repairing hernias, pelvic floor disorders, and in breast reconstructions.
    Type: Application
    Filed: January 23, 2015
    Publication date: October 22, 2015
    Inventors: Stephen F. Badylak, Matthew T. Wolf