Patents by Inventor Matthew Tobin

Matthew Tobin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Evolution of whole cells and organisms by recursive sequence recombination
    Publication number: 20070026446
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: August 17, 2006
    Publication date: February 1, 2007
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem Stemmer, Jon Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph Affholter
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 7148054
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: December 12, 2006
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin, Willem P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda A. Castle, Claus M. Krebber, Steve Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A. Affholter
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Publication number: 20060142950
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 29, 2006
    Applicant: Maxygen, Inc
    Inventors: Sergey Selifonov, Willem Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip Patten, Jeremy Minshull, Lorraine Giver
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Patent number: 7058515
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: June 6, 2006
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Patent number: 7024312
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: April 4, 2006
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Publication number: 20050191688
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: March 7, 2005
    Publication date: September 1, 2005
    Applicant: Maxygen, Inc.
    Inventors: Sergey Selifonov, Willem Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip Patten, Jeremy Minshull
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Patent number: 6917882
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: July 12, 2005
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6716631
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: April 6, 2004
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin, William P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten
  • Evolution of whole cells and organisms by recursive sequence recombination
    Publication number: 20030148309
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites
    Type: Application
    Filed: July 11, 2002
    Publication date: August 7, 2003
    Applicant: Maxygen, Inc.
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda A. Castle, Claus M. Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A. Affholter
  • Integrated systems and methods for diversity generation and screening
    Publication number: 20030064393
    Abstract: Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.
    Type: Application
    Filed: May 23, 2002
    Publication date: April 3, 2003
    Applicant: Maxygen, Inc.
    Inventors: Steven H. Bass, S. Christopher Davis, Phillip A. Patten, Matthew Tobin, Jeremy Minshull, Mark Welch, Claes Gustafsson, Brian Carr, Stephane Jenne, Sun Ai Raillard, Andreas Crameri, Willem P.C. Stemmer, Robin Emig, Pascal Longchamp, Stanley Goldman, Lorraine J. Giver, Joseph A. Affholter
  • Integrated systems and methods for diversity generation and screening
    Publication number: 20030054384
    Abstract: Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.
    Type: Application
    Filed: May 23, 2002
    Publication date: March 20, 2003
    Applicant: Maxygen, Inc.
    Inventors: Steven H. Bass, S. Christopher Davis, Phillip A. Patten, Matthew Tobin, Jeremy Minshull, Mark Welch, Claus Gustafsson, Brian Carr, Stephane Jenne, Sun Ai Raillard, Andreas Crameri, Willem P.C. Stemmer, Robin Emig, Pascal Longschamp, Stanley Goldman, Lorraine J. Giver, Joseph A. Affholter
  • Integrated systems and methods for diversity generation and screening
    Publication number: 20030054383
    Abstract: Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.
    Type: Application
    Filed: May 23, 2002
    Publication date: March 20, 2003
    Applicant: Maxygen, Inc.
    Inventors: Steven H. Bass, S. Christopher Davis, Phillip A. Patten, Matthew Tobin, Jeremy Minshull, Mark Welch, Claes Gustafsson, Brian Carr, Stephane Jenne, Sun Ai Raillard, Andreas Crameri, Willem P.C. Stemmer, Robin Emig, Pascal Longschamp, Stanley Goldman, Lorraine J. Giver, Joseph A. Affholter
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6528311
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: March 4, 2003
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin, William P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus M. Krebber, Steve Bass
  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Publication number: 20020183934
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: January 18, 2000
    Publication date: December 5, 2002
    Inventors: Sergey A. Selifonov, Willem P.C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull
  • Enantioselective production of amino carboxylic acids
    Publication number: 20020137153
    Abstract: Enantioselective or enantiospecific nitrilases and nitrile hydratases are used to produce R or S enantiomers of amides, and carboxylic acids. R-amino acids and S-amino acids are produced using such enantioselective enzymes. In addition, methods of producing and screening enantioselective nitrilases and nitrile hydratases are provided.
    Type: Application
    Filed: October 4, 2001
    Publication date: September 26, 2002
    Inventors: Sandra W. Ramer, Gjalt Huisman, Jim Millis, Roger Sheldon, Stephen delCardayre, Matthew Tobin, Anthony Cox, S. Christopher Davis
  • Molecular breeding of transposable elements
    Publication number: 20020072097
    Abstract: Methods for producing transposable elements with improved properties as vectors are provided. Directed evolution procedures are employed to improve characteristics of transposable elements, including transposons and insertion sequences as vectors. Methods for generating diversity in vivo and in vitro using transposable elements as vectors are provided.
    Type: Application
    Filed: July 5, 2001
    Publication date: June 13, 2002
    Inventors: Stephen delCardayre, Ranjan Patnaik, Phillip Patten, Matthew Tobin, Jon E. Ness, Anthony Cox, Lorraine J. Giver, Kevin McBride, Kenneth Zahn
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6379964
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: April 30, 2002
    Assignee: Maxygen, Inc.
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem P. C. Stemmer, Jeremy Minshull
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6352859
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: March 5, 2002
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin, William P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda Castle, Claus M. Krebber, Steve Bass
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6335198
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: January 1, 2002
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6326204
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: December 4, 2001
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin, William P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda Castle, Steve Bass