Patents by Inventor Matthias Bochtler

Matthias Bochtler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted RNA knockdown and knockout by type III-A Csm complexes
    Patent number: 11274317
    Abstract: Methods and compositions using a CRISPR-Cas Type IIIA resulting in RNA gene knockdown and knockout in an animal.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: March 15, 2022
    Assignee: VILNIUS UNIVERSITY
    Inventors: Thomas Fricke, Matthias Bochtler, Gintautas Tamulaitis, Miglé Kazlauskiene, Virginijus {hacek over (S)}ik{hacek over (s)}nys
  • TARGETED RNA KNOCKDOWN AND KNOCKOUT BY TYPE III-A Csm COMPLEXES
    Publication number: 20180105835
    Abstract: Methods and compositions using a CRISPR-Cas Type IIIA resulting in RNA gene knockdown and knockout in an animal.
    Type: Application
    Filed: August 31, 2017
    Publication date: April 19, 2018
    Inventors: Thomas FRICKE, Matthias BOCHTLER, Gintautas TAMULAITIS, Migle KAZLAUSKIENE, Virginijus SIKSNYS
  • Method of peptide hydrolysis, peptidase, the composition for use as a bacteriostatic and bactericidal agent, a kit and the uses of the active form of LytM from or derivatives thereof
    Patent number: 9487771
    Abstract: The invention relates to new method of peptide hydrolysis, in particular of the cell walls of Gram-positive bacteria, wherein the active form of LytM or derivative thereof is contacted with a peptide substrate, preferably with the cell walls of Gram-positive bacteria, in an aqueous environment of conductivity lower than 10 mS/cm. The invention also relates to composition comprising active form of LytM or derivative thereof and new uses of active form of LytM or derivative thereof.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: November 8, 2016
    Assignee: MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ
    Inventors: Izabela Sabala, Matthias Bochtler
  • METHOD OF PEPTIDE HYDROLYSIS, PEPTIDASE, THE COMPOSITION FOR USE AS A BACTERIOSTATIC AND BACTERICIDAL AGENT, A KIT AND THE USES OF THE ACTIVE FORM OF LYTM FROM S. AUREUS OR DERIVATIVES THEREOF
    Publication number: 20140044698
    Abstract: The invention relates to new method of peptide hydrolysis, in particular of the cell walls of Gram-positive bacteria, wherein the active form of LytM or derivative thereof is contacted with a peptide substrate, preferably with the cell walls of Gram-positive bacteria, in an aqueous environment of conductivity lower than 10 mS/cm. The invention also relates to composition comprising active form of LytM or derivative thereof and new uses of active form of LytM or derivative thereof.
    Type: Application
    Filed: October 17, 2013
    Publication date: February 13, 2014
    Applicant: MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ
    Inventors: Izabela Sabala, Matthias Bochtler