Patents by Inventor Matthias Bohn
Matthias Bohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190326017Abstract: Apparatus and methods for calculating cardiac output (CO) of a living subject using applanation tonometry measurements. In one embodiment, the apparatus and methods build a nonlinear mathematical model to correlate physiologic source data vectors to target CO values. The source data vectors include one or more measurable or derivable parameters such as: systolic and diastolic pressure, pulse pressure, beat-to-beat interval, mean arterial pressure, maximal slope of the pressure rise during systole, the area under systolic part of the pulse pressure wave, gender (male or female), age, height and weight. The target CO values are acquired using various methods, across a plurality of individuals. Multidimensional nonlinear optimization is then used to find a mathematical model which transforms the source data to the target CO data. The model is then applied to an individual by acquiring physiologic data for the individual and applying the model to the collected data.Type: ApplicationFiled: April 23, 2018Publication date: October 24, 2019Inventors: Oliver Goedje, Matthias Bohn, Patrick Hunziker, Oleksii Morozov, Felix Friedrich
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Patent number: 9949696Abstract: Apparatus and methods for calculating cardiac output (CO) of a living subject using applanation tonometry measurements. In one embodiment, the apparatus and methods build a nonlinear mathematical model to correlate physiologic source data vectors to target CO values. The source data vectors include one or more measurable or derivable parameters such as: systolic and diastolic pressure, pulse pressure, beat-to-beat interval, mean arterial pressure, maximal slope of the pressure rise during systole, the area under systolic part of the pulse pressure wave, gender (male or female), age, height and weight. The target CO values are acquired using various methods, across a plurality of individuals. Multidimensional nonlinear optimization is then used to find a mathematical model which transforms the source data to the target CO data. The model is then applied to an individual by acquiring physiologic data for the individual and applying the model to the collected data.Type: GrantFiled: March 14, 2013Date of Patent: April 24, 2018Assignee: TENSYS MEDICAL, INC.Inventors: Oliver Goedje, Matthias Bohn, Patrick Hunziker, Oleksii Morozov, Felix Friedrich
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Patent number: 9655530Abstract: Improved apparatus and methods for non-invasively assessing one or more physiologic (e.g., hemodynamic) parameters associated with a living organism. In one embodiment, the invention comprises an apparatus adapted to automatically and accurately place and maintain a sensor (e.g., tonometric pressure sensor) with respect to the anatomy of the subject. The apparatus is comprised of a sensor device removably coupled to a host device which is used to position the sensor during measurements. Methods for positioning the alignment apparatus and sensor, and operating the apparatus, are also disclosed.Type: GrantFiled: April 29, 2011Date of Patent: May 23, 2017Assignee: Tensys Medical, Inc.Inventors: Dave Eshbaugh, Oliver Goedje, Matthias Bohn
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Publication number: 20140275937Abstract: Apparatus and methods for calculating cardiac output (CO) of a living subject using applanation tonometry measurements. In one embodiment, the apparatus and methods build a nonlinear mathematical model to correlate physiologic source data vectors to target CO values. The source data vectors include one or more measurable or derivable parameters such as: systolic and diastolic pressure, pulse pressure, beat-to-beat interval, mean arterial pressure, maximal slope of the pressure rise during systole, the area under systolic part of the pulse pressure wave, gender (male or female), age, height and weight. The target CO values are acquired using various methods, across a plurality of individuals. Multidimensional nonlinear optimization is then used to find a mathematical model which transforms the source data to the target CO data. The model is then applied to an individual by acquiring physiologic data for the individual and applying the model to the collected data.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Inventors: Oliver Goedje, Matthias Bohn, Patrick Hunziker, Oleksii Morozov, Felix Friedrich
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Patent number: 8530391Abstract: A device for coating at least one substrate or for producing at least one molding by means of at least one cold gas spraying pistol, wherein the cold gas spraying pistol and the substrate or molding to be coated are arranged in a vacuum chamber, and also a method for cold gas spraying relating thereto in such a manner that while eliminating the wire production, the coil winding and also the cast in procedure, a thoroughly compact coil without a degree of freedom of movement (elimination of the quench risk) can be produced, it is suggested that the particles have at least to some extent an electrically conducting, in particular superconducting, property and at least to some extent an electrically poorly conducting or electrically insulating property.Type: GrantFiled: April 29, 2009Date of Patent: September 10, 2013Assignee: Linde AktiengesellschaftInventor: Matthias Bohn
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Patent number: 8521248Abstract: In a fiber-optic probe for intravascular measurements, e.g. oxygen saturation measurements, the fiber-optical core has only two fibers. A single fiber core is also possible. A reinforcement fiber improves stiffness, kink resistance and overall strength of the probe. The reinforcement fiber is arranged essentially parallel to the core fibers. The reinforcement fiber may also be wound around the core in a helical manner thus improving the mechanical properties to an even higher degree. The outside of the sheath is coated with an antithrombogenic coating for reducing the danger of clots forming at the surface. The reinforcement fiber may be made of carbon, metal, ceramics or aramide.Type: GrantFiled: August 19, 2009Date of Patent: August 27, 2013Assignee: PULSION Medical Systems SEInventors: Marcus Veeck, Oliver Goedje, Robert Herz, Thomas Thalmeier, Christoph Manegold, Matthias Bohn
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Publication number: 20130025716Abstract: A device for discharging a gaseous medium contains a discharge line, in which a safety valve and a gas jet compressor connected downstream from the safety valve are arranged. Furthermore, at least one storage container is preferably assigned to the gas jet compressor.Type: ApplicationFiled: February 1, 2012Publication date: January 31, 2013Inventor: Matthias Bohn
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Publication number: 20120277597Abstract: Improved apparatus and methods for non-invasively assessing one or more physiologic (e.g., hemodynamic) parameters associated with a living organism. In one embodiment, the invention comprises an apparatus adapted to automatically and accurately place and maintain a sensor (e.g., tonometric pressure sensor) with respect to the anatomy of the subject. The apparatus is comprised of a sensor device removably coupled to a host device which is used to position the sensor during measurements. Methods for positioning the alignment apparatus and sensor, and operating the apparatus, are also disclosed.Type: ApplicationFiled: April 29, 2011Publication date: November 1, 2012Inventors: Dave Eshbaugh, Oliver Goedje, Matthias Bohn
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Publication number: 20110289765Abstract: A method and device for producing a compact and/or massive multi-layer coil by means of dynamic cold spraying, electrically conductive connections are created between the individual conductor layers, which are embedded in the support material, in particular between the individual conductor tracks.Type: ApplicationFiled: November 16, 2010Publication date: December 1, 2011Inventors: Matthias Bohn, Werner Krömmer
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Publication number: 20110238020Abstract: The invention relates to a catheter device with an integrated fiber optic, in particular for use in thermodilution measurement and pulse contour analysis. The device comprises an arterial catheter (2) with a suitable intravascular part and a suitable extravascular part and an optical sensor unit for combined pressure and temperature measurement at a measurement location at the distal end of the suitable intravascular part or proximate to the distal end of the proper intravascular part of the catheter (2). The optical sensor unit comprises a fiber optic conductor (11) that runs from the measurement location to a proximal port.Type: ApplicationFiled: September 2, 2009Publication date: September 29, 2011Applicant: PULSION Medical systems AGInventors: Oliver Goedje, Marcus Veeck, Robert Herz, Matthias Bohn, Stephan Joeken
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Publication number: 20110179811Abstract: Methods for filling magnets, cooling magnets and energizing magnets are disclosed. The methods are performed at a helium transfill facility, and helium is employed in filling the magnet, cooling the magnet to appropriate temperatures and energizing the magnet such that it can be employed in operations where superconductive magnets are required.Type: ApplicationFiled: March 2, 2010Publication date: July 28, 2011Inventors: Matthias Bohn, Niels Lose, Dan Baciu
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Patient monitoring apparatus and method for determining volume responsiveness of a monitored patient
Patent number: 7850617Abstract: From the global end-diastolic volume GEDV and the global ejection fraction GEF the patient monitor (4) determines a corrected global end-diastolic volume cGEDV according to cGEDV=GEDV/ƒ(GEF) which is used as a novel parameter for volume responsiveness of the patient (3). In the above formula, f(GEF) is a correction function depending on global ejection fraction GEF. Further, from the right ventricular end-diastolic volume RVEDV and the right ventricular ejection fraction RVEF the patient monitor (4) determines a corrected right ventricular end-diastolic volume cRVEDV according to cRVEDV=RVEDV1f(RVEF) which is used as another novel parameter for volume responsiveness of the patient (3). In the above formula, f(RVEF) is a correction function depending on right ventricular ejection fraction RVEF.Type: GrantFiled: April 5, 2007Date of Patent: December 14, 2010Assignee: Pulsion Medical Systems AGInventors: Oliver Goedje, Manu Malbrain, Stephan Joeken, Matthias Bohn -
Publication number: 20100049019Abstract: In a fiber-optic probe for intravascular measurements, e.g. oxygen saturation measurements, the fiber-optical core has only two fibers. A single fiber core is also possible. A reinforcement fiber improves stiffness, kink resistance and overall strength of the probe. The reinforcement fiber is arranged essentially parallel to the core fibers. The reinforcement fiber may also be wound around the core in a helical manner thus improving the mechanical properties to an even higher degree. The outside of the sheath is coated with an antithrombogenic coating for reducing the danger of clots forming at the surface. The reinforcement fiber may be made of carbon, metal, ceramics or aramide.Type: ApplicationFiled: August 19, 2009Publication date: February 25, 2010Inventors: Marcus Veeck, Oliver Goedje, Robert Herz, Thomas Thalmeier, Christoph Manegold, Matthias Bohn
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Publication number: 20090291851Abstract: A device for coating at least one substrate or for producing at least one molding by means of at least one cold gas spraying pistol, wherein the cold gas spraying pistol and the substrate or molding to be coated are arranged in a vacuum chamber, and also a method for cold gas spraying relating thereto in such a manner that while eliminating the wire production, the coil winding and also the cast in procedure, a thoroughly compact coil without a degree of freedom of movement (elimination of the quench risk) can be produced, it is suggested that the particles have at least to some extent an electrically conducting, in particular superconducting, property and at least to some extent an electrically poorly conducting or electrically insulating property.Type: ApplicationFiled: April 29, 2009Publication date: November 26, 2009Inventor: Matthias BOHN
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Publication number: 20080077043Abstract: The catheter has a proximal port with an opening of a feeding lumen. There are two further openings in another proximal port with a connector, to which a source/sink of gas pressure and a pressure gauge can be connected. The interior of a distal balloon communicates with the opening and can hence be inflated and deflated through that opening in order to measure intra-abdominal pressure using the pressure gauge. A reflux filter is integrated into the connector. In the upper connector piece or lower connector piece a recess surrounding the measurement lumen is provided at the contact surface between the connector pieces. The gas-permeable filter membrane is disposed in the recess for preventing liquids in the lumen from entering from the lower connector piece into the upper connector piece and thus from passing through the opening in case of rupture or leakage of the distal balloon.Type: ApplicationFiled: August 20, 2007Publication date: March 27, 2008Inventors: Manu Malbrain, Robert Herz, Matthias Bohn, Oliver Goedje
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Patient monitoring apparatus and method for determining volume responsiveness of a monitored patient
Publication number: 20070287929Abstract: From the global enddiastolic volume GEDV and the global ejection fraction GEF the patient monitor (4) determines a corrected global enddiastolic volume cGEDV according to cGEDV=GEDV/f(GEF) which is used as a novel paramater for volume responsiveness of the patient (3). In the above formula, f(GEF) is a correction function depending on global ejection fraction GEF. Further, from the right ventricular enddiastolic volume RVEDV and the right ventricular ejection fraction RVEF the patient monitor (4) determines a corrected right ventricular enddiastolic volume cRVEDV according to cRVEDV=RVEDV/f(RVEF) which is used as another novel paramater for volume responsiveness of the patient (3). In the above formula, f(RVEF) is a correction function depending on right ventricular ejection fraction RVEF.Type: ApplicationFiled: April 5, 2007Publication date: December 13, 2007Inventors: Oliver Goedje, Manu Malbrain, Stefan Joeken, Matthias Bohn -
Publication number: 20070175828Abstract: The device according to the invention serves to set up a dilution measurement site on a hemodialyzer. Using such a measurement site, it is possible to determine the filling status of a dialysis patient during dialysis treatment, by means of dilution measurements. Checking the fluid balance by means of weighing the dialysis patient, which is subject to error, can be eliminated. The arterial connection piece is connected with an arterial fistula needle, and the venous connection piece is connected with a venous fistula needle as the blood vessel access. The venous connection piece has an injection channel through which a bolus required to perform a dilution measurement can be injected into the blood, which flows through the venous connection piece coming from the hemodialyzer, in the direction of the venous blood vessel access.Type: ApplicationFiled: January 30, 2007Publication date: August 2, 2007Inventors: Oliver Goedje, Thomas Thalmeier, Matthias Bohn
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Publication number: 20070073180Abstract: Disclosed is an apparatus, a computer system, a computer program, a temperature sensor device and a heat transfer device by which thermodilution measurements can be carried out in a non-invasive or less invasive manner by using extravascular (transcutaneous or subcutaneous) temperature sensor devices and/or extravascular heat transfer devices.Type: ApplicationFiled: September 26, 2006Publication date: March 29, 2007Inventors: Matthias Bohn, Oliver Goedje, Thomas Thalmeier