Patents by Inventor Matthias E LIECHTI

Matthias E LIECHTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of quantifying lysergic acid diethylamide (LSD) and 2,3-dihydro-3-hydroxy-2-oxo lysergide (O-H-LSD) in human plasma
    Patent number: 11959929
    Abstract: A method of measuring and identifying LSD and its major metabolite O-H-LSD, by obtaining a sample from an individual, and measuring, identifying, and quantifying LSD and O-H-LSD in the sample by performing a LC-MS/MS analysis. A method of treating and monitoring individuals taking LSD, by administering a microdose of LSD, a prodrug of LSD, or an analog of LSD to the individual, monitoring the individual by obtaining a sample from an individual and measuring and identifying the analytes in the sample by performing a LC-MS/MS analysis, and adjusting the microdose based on the amount of LSD quantified in the LC-MS/MS analysis. A method of adjusting dosing of LSD, by administering a microdose of LSD, a prodrug of LSD, or an analog of LSD to the individual, and adjusting the microdose based on blood concentration analytics.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: April 16, 2024
    Assignee: Universitätsspital Basel
    Inventors: Matthias E. Liechti, Urs Philipp Duthaler
  • METHOD OF QUANTIFYING LYSERGIC ACID DIETHYLAMIDE (LSD) AND 2,3-DIHYDRO-3-HYDROXY-2-OXO LYSERGIDE (O-H-LSD) IN HUMAN PLASMA
    Publication number: 20220128580
    Abstract: A method of measuring and identifying LSD and its major metabolite O-H-LSD, by obtaining a sample from an individual, and measuring, identifying, and quantifying LSD and O-H-LSD in the sample by performing a LC-MS/MS analysis. A method of treating and monitoring individuals taking LSD, by administering a microdose of LSD, a prodrug of LSD, or an analog of LSD to the individual, monitoring the individual by obtaining a sample from an individual and measuring and identifying the analytes in the sample by performing a LC-MS/MS analysis, and adjusting the microdose based on the amount of LSD quantified in the LC-MS/MS analysis. A method of adjusting dosing of LSD, by administering a microdose of LSD, a prodrug of LSD, or an analog of LSD to the individual, and adjusting the microdose based on blood concentration analytics.
    Type: Application
    Filed: October 20, 2021
    Publication date: April 28, 2022
    Inventors: Matthias E. LIECHTI, Urs Philipp DUTHALER
  • METHOD OF QUANTIFYING PSILOCYBIN'S MAIN METABOLITES, PSILOCIN AND 4-HYDROXYINDOLE-3-ACETIC ACID, IN HUMAN PLASMA
    Publication number: 20220082578
    Abstract: A method of measuring and identifying metabolites of a tryptamine compound, by obtaining a sample from an individual, and measuring and identifying metabolites of the tryptamine compound in the sample by performing a LC-MS/MS analysis. A method of adjusting dosing in patients with tryptamine compound-assisted psychotherapy in therapeutic drug monitoring (TDM), by obtaining a sample from an individual, measuring and identifying metabolites of the tryptamine compounds in the sample by performing a LC-MS/MS analysis, and adjusting a dose of the tryptamine compounds based on the measured metabolites.
    Type: Application
    Filed: August 14, 2021
    Publication date: March 17, 2022
    Inventors: Matthias E LIECHTI, Karolina Elzbieta KOLACZYNSKA, Urs Philipp DUTHALER