Abstract: The invention relates to an implant comprising an active-agent-containing coating which covers the implant at least in sections. The coating is composed of at least two subsections; a first subsection contains the at least one active substance, and a second subsection contains an auxiliary agent.

Abstract: The invention relates to an implantation device (10a-d) comprising at least one medical implant (12a-d) and at least one implantation aid (14a-d) comprising at least one expansion element (16a-d). It is provided that the expansion element (16a-d) can be inserted into at least one cavity (18a-d) of the implant (12a-d), and the at least one cavity (18a-d) can be expanded using the expansion element (16a-d), and, in the end state, the expansion element (16a-d) is disposed at least partially in the at least one cavity (18a-d), wherein the expansion element (16a-d) is designed as a solid body (20a-d).

Abstract: An implant having a preferably hollow cylindrical main structure comprising a large number of continuous openings and a coating which releases at least one pharmaceutically active substance. To attain a better distribution of the pharmaceutically active substance, at least 20% of the cross-sectional area, preferably at least 50% of the cross-sectional area, of at least a portion of the openings in a predetermined section of the main structure is covered with the coating which releases at least one pharmaceutically active substance. Furthermore, a system composed of a catheter and such an implant, a simple method for manufacturing such an implant or such a system is provided.

Abstract: An agent depot for mechanical connection to a surface of an endovascular implantable body, comprising one or more polymers, one or more bioactive agents, the agent depot being mechanically connectable to the implantable body by a force fit or an adhesive.

Abstract: A stent comprising a degradable metal stent main body; a partition layer which is applied to the surface of the stent main body so that at least parts of the surface of the luminal side are not covered; and an agent-containing layer which is applied to the surface of the partition layer at least partially on the abluminal side of the stent main body and comprises one or more agents and possibly one or more polymers.

Abstract: An implant system comprising a functional implant (5, 6) that fulfills a medical function, particularly a bone implant, which is formed at least in part of a metal material that can be degraded by the body (2) of the implant wearer, as well as a control device (7) for controlling the degradation behavior of the functional implant (5, 6). The control device (7) has a counter-electrode (10) to the functional implant (5, 6), and a voltage source (8) for making available a polarization voltage (?U) between functional implant (5, 6, 15) and counter-electrode (10), to control the degradation behavior of the functional implant (5, 6).

Abstract: An implant comprising a body (1), at least one active pharmaceutical substance (4) and an element (5, 15, 35, 45, 55) deflectable in relation to the body, serving to release the at least one active pharmaceutical substance (4) during or after an external excitation of the deflection. Also disclosed is a system of such an implant and an excitation device (30, 70).

Abstract: An implant having a preferably hollow cylindrical main structure comprising a large number of continuous openings and a coating which releases at least one pharmaceutically active substance. To attain a better distribution of the pharmaceutically active substance, at least 20% of the cross-sectional area, preferably at least 50% of the cross-sectional area, of at least a portion of the openings in a predetermined section of the main structure is covered with the coating which releases at least one pharmaceutically active substance. Furthermore, a system composed of a catheter and such an implant, a simple method for manufacturing such an implant or such a system is provided.

Abstract: The invention relates to an implantation device (10a-d) comprising at least one medical implant (12a-d) and at least one implantation aid (14a-d) comprising at least one expansion element (16a-d). It is provided that the expansion element (16a-d) can be inserted into at least one cavity (18a-d) of the implant (12a-d), and the at least one cavity (18a-d) can be expanded using the expansion element (16a-d), and, in the end state, the expansion element (16a-d) is disposed at least partially in the at least one cavity (18a-d), wherein the expansion element (16a-d) is designed as a solid body (20a-d).

Abstract: The invention relates to a medical valve implant (10a-d), in particular a heart valve implant (12a-d), for implantation in an animal body and/or human body, comprising a support frame (14a-d) which has at least one wall (16a-d). It is provided that one region (18a-d) of the at least one wall (16a-d) of the support frame (14a-d) is curable.

Abstract: The invention relates to an implant comprising an active-agent-containing coating which covers the implant at least in sections. The coating is composed of at least two subsections; a first subsection contains the at least one active substance, and a second subsection contains an auxiliary agent.

Abstract: The present invention relates to a catheter comprising a balloon (10, 30) and at least one pharmaceutically active substance. To enable more accurate dosing of the pharmaceutically active substance, the pharmaceutically active substance is disposed in a reservoir (15, 35) inside the balloon (10, 30) or on the balloon (10, 30), wherein a wall (14, 32, 34) that closes the reservoir toward the outside comprises at least one predetermined breaking point (16). Furthermore, a system for applying an intraluminal endoprosthesis, preferably a stent, in a body cavity, and simple and cost-effective methods for manufacturing the catheter and the system are described.

Abstract: An agent depot for mechanical connection to a surface of an endovascular implantable body, comprising one or more polymers, one or more bioactive agents, the agent depot being mechanically connectable to the implantable body by a force fit or an adhesive.

Abstract: A method for producing an agent depot for mechanical connection to a surface of an endovascular implantable body, comprising a) providing one or more polymers; b) providing one or more agents; and c) producing an agent depot from said polymers and said agents, the agent depot being mechanically connectable to the surface of the body using force action or adhesive.

Abstract: An endoprosthesis, in particular, an intraluminal endoprosthesis, e.g., a stent, having a basic mesh and a functional element attached to a carrier structure, the functional element having a different material composition than the material of the basic mesh in at least a portion of its volume. The carrier structure is arranged on the basic mesh in the first essentially finger-shaped end and protrudes away from the mesh essentially like a projection. The functional element is arranged on an area of the carrier structure protruding away from the base body and at least partially surrounds the area of the carrier structure.

Abstract: A system for introducing an intraluminal endoprosthesis (30), preferably a stent, into a body cavity. The system consists of the intraluminal endoprosthesis (30) and a catheter with a balloon (10), the balloon (10) having at least one wing (12) in an undilated condition. The system has at least one active pharmaceutical substance (20) arranged at least partially beneath the at least one wing (12) of the balloon (10) in the undilated condition. The intraluminal endoprosthesis (30) is fixedly arranged on the folded balloon (10) such that the endoprosthesis surrounds the balloon at least partially and protects the at least one active pharmaceutical substance (20) from being washed out and rubbed off. Further disclosed is a method for manufacturing such a system.

Abstract: An implant system comprising a functional implant (5, 6) that fulfills a medical function, particularly a bone implant, which is formed at least in part of a metal material that can be degraded by the body (2) of the implant wearer, as well as a control device (7) for controlling the degradation behavior of the functional implant (5, 6). The control device (7) has a counter-electrode (10) to the functional implant (5, 6), and a voltage source (8) for making available a polarization voltage (?U) between functional implant (5, 6, 15) and counter-electrode (10), to control the degradation behavior of the functional implant (5, 6).

Abstract: A stent having a base body of a bioinert metallic implant material wherein the base body is covered with an SiC coating. An external surface of the base body has a plurality of cavities which are filled with an antiproliferative active ingredient, A luminal surface of the base body has a coating which contains or comprises attractors for endothelial cells.

Abstract: A stent comprising a degradable metal stent main body; a partition layer which is applied to the surface of the stent main body so that at least parts of the surface of the luminal side are not covered; and an agent-containing layer which is applied to the surface of the partition layer at least partially on the abluminal side of the stent main body and comprises one or more agents and possibly one or more polymers.

Abstract: A method for producing an agent depot for mechanical connection to a surface of an endovascular implantable body, comprising a) providing one or more polymers; b) providing one or more agents; and c) producing an agent depot from said polymers and said agents, the agent depot being mechanically connectable to the surface of the body using force action or adhesive.