Patents by Inventor Matthias Hediger

Matthias Hediger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for transporting vitamin C
    Patent number: 7371536
    Abstract: The invention provides methods for regulating the transport of vitamin C across membranes.
    Type: Grant
    Filed: April 7, 2003
    Date of Patent: May 13, 2008
    Inventor: Matthias A. Hediger
  • Methods of altering calcium transport
    Patent number: 7078178
    Abstract: Methods of altering transmembrane calcium transport by altering expression of a calcium-transport protein are described.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: July 18, 2006
    Inventors: Matthias A. Hediger, Edward M. Brown, Ji-Bin Peng
  • Compositions corresponding to a calcium transporter and methods of making and using same
    Publication number: 20040137620
    Abstract: Nucleic-acid and amino-acid sequences correspond to a calcium-transport protein regulating the movement of calcium across cell membranes.
    Type: Application
    Filed: December 23, 2002
    Publication date: July 15, 2004
    Applicant: Matthias A. Hediger
    Inventors: Matthias A. Hediger, Edward M. Brown, Ji-Bin Peng
  • Methods for transporting vitamin C transporter and related methods
    Publication number: 20040006019
    Abstract: The invention provides methods for regulating the transport of vitamin C across membranes.
    Type: Application
    Filed: April 7, 2003
    Publication date: January 8, 2004
    Applicant: Matthias A. Hediger
    Inventor: Matthias A. Hediger
  • Methods of altering calcium transport
    Publication number: 20030211613
    Abstract: Methods of altering transmembrane calcium transport by altering expression of a calcium-transport protein are described.
    Type: Application
    Filed: April 22, 2003
    Publication date: November 13, 2003
    Inventors: Matthias A. Hediger, Edward M. Brown, Ji-Bin Peng
  • Compositions corresponding to a calcium transporter and methods of making and using same
    Patent number: 6534642
    Abstract: Nucleic-acid and amino-acid sequences correspond to a calcium-transport protein regulating the movement of calcium across cell membranes.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: March 18, 2003
    Inventors: Matthias A. Hediger, Edward M. Brown, Ji-Bin Peng
  • Compositions corresponding to a proton-coupled peptide transporter and methods of making and using same
    Patent number: 5849525
    Abstract: The present invention relates to nucleic acid and amino acid sequences corresponding to a proton-coupled peptide transporter and methods of making and using such transporter.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: December 15, 1998
    Assignee: Brigham and Women's Hospital, Inc.
    Inventor: Matthias Hediger
  • Compositions corresponding to a high-affinity glutamate transporter molecule and methods for making and using same
    Patent number: 5739284
    Abstract: The present invention features an excitatory amino acid carrier protein which has high affinity for glutamate and is associated with neuronal glutamate transport, and methods of making and using the protein.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: April 14, 1998
    Assignee: Brigham and Women's Hospital, Inc.
    Inventors: Matthias Hediger, Yoshikatsu Kanai
  • Urea transporter polypeptide
    Patent number: 5441875
    Abstract: An isolated nucleotide sequence encoding a urea transporter polypeptide or unique fragments of urea transporter polypeptide, is provided. One embodiment is an isolated DNA sequence (SEQ ID NO.:1) encoding a urea transporter polypeptide, that has at least two extended hydrophobic domains, each domain lacking interspersed hydrophilic domains. Also described are recombinant cells and plasmids containing the foregoing isolated DNA, preferably linked to a promoter. Isolated urea transporter polypeptide is provided, having at least two extended hydrophobic domains, each domain lacking interspersed hydrophilic domains (SEQ ID NO.:2). Portions of the foregoing isolated urea transporter polypeptides are also described. Antibodies with selective binding specificity for the polypeptides of the invention also are provided.Methods for producing urea transporter polypeptide as well as methods for testing for modulators of urea transporter polypeptide activity are also described.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: August 15, 1995
    Assignee: Brigham and Women's Hospital
    Inventor: Matthias A. Hediger
  • Method and apparatus for preparative gel electrophoresis
    Patent number: 4479861
    Abstract: A preparative gel electrophoresis apparatus comprises a first outer coolable cylinder, a second inner coolable cylinder within the outer cylinder, a compact column of separating material placed between the first and second cylinders and electrodes arranged above and below the separating column for forming an electrical field over the volume of the separating column, axially translatable adapters above and below the support, surrounding the electrodes, containing duct systems and completely surrounding the inner coolable cylinder. A method of forming the gel column by injecting gel while separating the adapters is also disclosed.
    Type: Grant
    Filed: July 19, 1983
    Date of Patent: October 30, 1984
    Inventor: Matthias Hediger