Patents by Inventor Matthias Heinrichs

Matthias Heinrichs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7205309
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3 and A have the significance given in the specification are provided. The compounds can be used for the treatment or prevention of obesity.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: April 17, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger
  • Publication number: 20070034115
    Abstract: The invention relates to a rheological additive comprising illite clay, smectic clay and an attapulgite suitable for controlling the application characteristics of a coating material for porous bodies.
    Type: Application
    Filed: March 18, 2004
    Publication date: February 15, 2007
    Inventors: Reinhard Stotzel, Herbert Pitamitz, Lothar Berger, Matthias Heinrich
  • Patent number: 7166589
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: January 23, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael G. Klug, Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Jean-Marc Plancher
  • Patent number: 7074436
    Abstract: A method for the production of an extract of Phyllanthus wherein (a) Phyllanthuscomponents are extracted with an ethanol/water mixture of 5–85% m/m to which a heavy-metal chelator is added at a concentration of 0.001–3% m/m; (b) the primary extract obtained in step (a) is contacted and concentrated with (ba) Indian Sterculia gum at a final concentration of 0.5–5.0% mm relative to the sum of the extractive substances or (bb) one or more polymers and impendable and/or soluble substance(s); and (c) the concentrated extract obtained in step (b) is dried. The method according to the invention leads to particularly high yield of pharmaceutically effective plant ingredients and is thus of particular interest for therapeutic applications. In a preferred embodiment of the invention the method according to the invention includes a filtration step of the primary extract. It is further preferred that a lipoid is added during the extraction method. The Phyllanthus Phyllanthus amarus is preferred.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: July 11, 2006
    Assignee: Phytrix, Inc.
    Inventors: Matthias-Heinrich Kreuter, Hildebert K. M. Wagner, Gerolf Tittel
  • Patent number: 7064134
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: June 20, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael G. Klug, Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Jean-Marc Plancher
  • Publication number: 20060089367
    Abstract: Provided are compounds of the formula I: and pharmaceutically acceptable salts thereof, processes for making said compounds and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compound and pharmaceutically acceptable salts thereof, and methods of using said compounds. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Application
    Filed: October 25, 2005
    Publication date: April 27, 2006
    Inventors: Konrad Bleicher, Matthias Heinrich Nettekoven, Philippe Pflieger, Stephan Roever
  • Publication number: 20060085294
    Abstract: A multiple transaction quantity inventory management system including an inventory management component to store and manage inventory information using a base unit of measure (“UOM”) and in a valuation UOM related by at least one conversion factor for each of a plurality of goods; a material management component connected to the inventory management component, the material management component to monitor and maintain information on the plurality of goods in the base UOM and in the valuation UOM for each of the plurality of goods; a sales delivery component connected to the inventory management component, the sales delivery component to receive and process sales orders in the base UOM; a warehouse management component connected to the inventory management component, the warehouse management component to control stock information for the plurality of goods in a single UOM; and a financial component connected to the inventory management component, the material management component, the sales delivery component,
    Type: Application
    Filed: September 15, 2004
    Publication date: April 20, 2006
    Inventors: Stefan Boerner, Udo Laub, Matthias Heinrichs, Jochen Hirth
  • Patent number: 7022707
    Abstract: The present invention is a chemical compound of formula (I) or a pharmaceutically acceptable salts, solvates and esters thereof, wherein R1 to R4, A1, A2 m and n are as described in the specification.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: April 4, 2006
    Assignees: Hoffman-La Roche Inc., Vernalis Research Limited
    Inventors: David Reginald Adams, Jonathan Mark Bentley, James Edward Paul Davidson, Claire Elizabeth Dawson, Ashley Roger George, Howard Langham Mansell, Patrizio Mattei, Jacques Mizrahi, Matthias Heinrich Nettekoven, Robert Mark Pratt, Stephan Roever, Jonathan Richard Anthony Roffey, Jean-Luc Specklin, Henri Stalder, Kerry Wilkinson
  • Patent number: 7012073
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: July 22, 2004
    Date of Patent: March 14, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael G. Klug, Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Jean-Marc Plancher
  • Publication number: 20050260386
    Abstract: The invention concerns a decorated article, in particular a mobile telephone housing or a mobile telephone window, and a multi-layer film, in particular an IMD-able stamping film. The decorated article has a base body and at least one decorative element arranged on the surface of the base body. The decorative element has a transparent structure layer which has a spatial structure producing an optically perceptible effect, and a reflection layer arranged between the surface of the base body and the structure layer.
    Type: Application
    Filed: August 8, 2003
    Publication date: November 24, 2005
    Inventors: Matthias Heinrich, Andreas Hirschfelder
  • Patent number: 6900226
    Abstract: Quinoline and quinazoline derivatives can be used in the form of pharmaceutical preparations as Neuropeptide Y antagonists for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: May 31, 2005
    Assignee: Hoffman-La Roche Inc.
    Inventors: Volker Breu, Frank Dautzenberg, Philippe Guerry, Matthias Heinrich Nettekoven, Philippe Pflieger
  • Publication number: 20040266845
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: June 18, 2004
    Publication date: December 30, 2004
    Inventors: Matthias Heinrich Nettekoven, Stephan Roever
  • Publication number: 20040259858
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: July 22, 2004
    Publication date: December 23, 2004
    Inventors: Michael G. Klug, Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Jean-Marc Plancher
  • Publication number: 20040235859
    Abstract: The present invention is a chemical compound of formula (I) 1
    Type: Application
    Filed: June 23, 2004
    Publication date: November 25, 2004
    Inventors: David Reginald Adams, Jonathan Mark Bentley, James Edward Paul Davidson, Claire Elizabeth Dawson, Ashley Roger George, Howard Langham Mansell, Patrizio Mattei, Jacques Mizrahi, Matthias Heinrich Nettekoven, Robert Mark Pratt, Stephan Roever, Jonathan Richard Anthony Roffey, Jean-Luc Specklin, Henri Stalder, Kerry Wilkinson
  • Patent number: 6787585
    Abstract: A coating material for interior walls and exterior facades has heat reflection and oleophobicity/hydrophobicity, properties. The material is either opaque to visible light and/or contains a material which provides opacity. It includes: a) at least one silane of the formula (I) XaRbSiR14−a−b  (I)  in which X is a hydrolyzable group, R is optionally substituted alkyl, alkenyl, aryl, alkylaryl or arylalkyl, R1 is an organic radical which is attached to the silicon via carbon and carries a reactive group, a is an integer from 1 to 3, and b is an integer from 0 to 2, or a (partial) condensate of this silane, b) at least one infrared-reflecting pigment whose particle size is situated primarily in the range from 1 to 50 &mgr;m, and c) a solvent and/or dispersion medium.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: September 7, 2004
    Assignee: Fraunhofer-Gesellschaft zur Forderung
    Inventors: Klaus Rose, Matthias Heinrich, Karl-Heinz Haas, Michael Köhl
  • Patent number: 6787558
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: September 7, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael G. Klug, Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Jean-Marc Plancher
  • Publication number: 20040038990
    Abstract: Compounds of formula I 1
    Type: Application
    Filed: August 5, 2003
    Publication date: February 26, 2004
    Inventors: Wolfgang Guba, Patrizio Mattei, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger
  • Patent number: 6696467
    Abstract: Compounds of general formula I as well as pharmaceutically acceptable salts and esters thereof, are potent inhibitors of neuropeptide Y and can be used in the form of pharmaceutical preparations for the treatment or prevention of various disease states and related morbidities including obesity.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: February 24, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Patrizio Mattei, Werner Mueller, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger
  • Publication number: 20040033275
    Abstract: A method for the production of an extract of Phyllanthus wherein (a) Phyllanthus components are extracted with an ethanol/water mixture of 5-85% m/m to which a heavy-metal chelator is added at a concentration of 0.001-3% m/m; (b) the primary extract obtained in step (a) is contacted and concentrated with (ba) Indian Sterculia gum at a final concentration of 0.5-5.0% mm relative to the sum of the extractive substances or (bb) one or more polymers and impendable and/or soluble substance(s); and (c) the concentrated extract obtained in step (b) is dried. The method according to the invention leads to particularly high yield of pharmaceutically effective plant ingredients and is thus of particular interest for therapeutic applications. In a preferred embodiment of the invention the method according to the invention includes a filtration step of the primary extract. It is further preferred that a lipoid is added during the extraction method. The Phyllanthus Phyllanthus amarus is preferred.
    Type: Application
    Filed: September 4, 2003
    Publication date: February 19, 2004
    Inventors: Matthias-Heinrich Kreuter, Hildebert K.M. Wagner, Gerolf Tittel
  • Patent number: 6693116
    Abstract: The present application relates to compounds of the formula wherein R1 is hydrogen, halogen or lower alkoxy; R2 is hydrogen or is —C(O)-lower alkyl or —C(O)-phenyl, wherein the phenyl ring is unsubstituted or substituted by one or two substituents selected from the group consisting of halogen, lower alkyl, lower alkoxy and trifluoromethyl, or is —C(O)-furanyl or —C(O)-thiophenyl, wherein the rings are unsubstituted or substituted by halogen; or a pharmaceutically acceptable salt thereof. The compounds are useful in the treatment of diseases associated with the adenosine A2 receptor.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: February 17, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Matthias Heinrich Nettekoven, Sebastien Schmitt