Patents by Inventor Matthias Lohr

Matthias Lohr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCL12 (CHEMOKINE (C-X-C MOTIF) LIGAND 12) AND IGFBP2 INHIBITORS FOR THE APPLICATION IN THE TREATMENT OF DIABETES MELLITUS ASSOCIATED PANCREATIC CANCER
    Publication number: 20160215053
    Abstract: The subject of the invention is the application of CXCL12 (Chemokine (C-X-C motif) Ligand 12) and IGFBP2 inhibitors for the treatment of diabetes mellitus associated pancreatic cancer. The core of this invention is the discovery that the chronically increased glucose levels (chronic hyperglycemia) could may an important role in the development of the pancreatic cancer and that the development of the pancreatic cancer due to chronic hyperglycemia or an already developed pancreatic cancer may be prevented/inhibited/delayed by the inhibition of CXCL12 and IGFBP2. In addition the subject of the invention is the production of inhibitors for the application as a treatment of diabetes mellitus associated pancreatic cancer and pharmaceutical drugs containing the inhibitors.
    Type: Application
    Filed: August 27, 2014
    Publication date: July 28, 2016
    Inventors: Gábor Firneisz, Ralf Jesenofsky, Matthias Löhr
  • Specific mucin expression as a marker for pancreatic cancer
    Publication number: 20070003985
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Application
    Filed: May 30, 2006
    Publication date: January 4, 2007
    Inventors: Surinder Batra, Randall Brand, Joerg Ringel, Grit Faulmann, Matthias Lohr, Grish Varshney
  • Injection device and method for injecting capsules
    Patent number: 7083607
    Abstract: The invention relates to an injection device containing a hollow needle (1), a cutting needle that can be inserted into the hollow needle and that has a cutting tip projecting from the front end of the hollow needle, a catheter (9) that replaces said cutting needle and that can be inserted approximately up to its front end into the hollow needle (9), said catheter having a receiving chamber (30) for a substance in the form of a capsule on its distal end, in addition to a mandrin (29) that can be inserted into the catheter (9) and which can be placed in a position defining a receiving chamber (30) filled with capsules (22) on the distal end of said catheter, wherein the capsules (22) contained in the receiving chamber (30) of the inserted catheter (9) are released without exerting any pressure in the target area of the body (23) once the injection device has been arranged in a target area of a body (23) by relatively pulling back both the catheter (9) and the hollow needle (1) in relation to the mandrin (29) a
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: August 1, 2006
    Assignee: Bavarian Nordic A/S
    Inventors: Matthias Löhr, Walter Günzburg
  • MUCIN 4 expression as a marker for pancreatic cancer
    Patent number: 7052859
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: May 30, 2006
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Surinder K. Batra, Randall E Brand, Jöerg Ringel, Grit Faulmann, Matthias Löhr, Grish C. Varshney
  • Encapsulated cells producing cytochrome P450
    Patent number: 6893634
    Abstract: The present invention relates to capsules encapsulating cytochrome P450 producing cells and cytochrome P450 producing retroviral packaging cells. Furthermore, the present invention relates to the treatment of cancer or any other relevant disease with said capsules and to the use of said capsules for the preparation of a pharmaceutical composition for said treatment.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: May 17, 2005
    Assignees: GSF-Forschungszentrum fur Umwelt und Gesundheit GmbH, Bavarian Nordic A/S
    Inventors: Walter H. Günzburg, Peter Karle, Robert Saller, Brian Salmons, Matthias Löhr, Peter Müller
  • Injection device and method for injecting capsules
    Publication number: 20040199120
    Abstract: The invention relates to an injection device containing a hollow needle (1), a cutting needle that can be inserted into the hollow needle and that has a cutting tip projecting from the front end of the hollow needle, a catheter (9) that replaces said cutting needle and that can be inserted approximately up to its front end into the hollow needle (9), said catheter having a receiving chamber (30) for a substance in the form of a capsule on its distal end, in addition to a mandrin (29) that can be inserted into the catheter (9) and which can be placed in a position defining a receiving chamber (30) filled with capsules (22) on the distal end of said catheter, wherein the capsules (22) contained in the receiving chamber (30) of the inserted catheter (9) are released without exerting any pressure in the target area of the body (23) once the injection device has been arranged in a target area of a body (23) by relatively pulling back both the catheter (9) and the hollow needle (1) in relation to the mandrin (29) a
    Type: Application
    Filed: February 19, 2004
    Publication date: October 7, 2004
    Inventors: Matthias Lohr, Walter Gunzburg
  • Specific mucin expression as a marker for pancreatic cancer
    Publication number: 20030134343
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Application
    Filed: October 24, 2002
    Publication date: July 17, 2003
    Inventors: Surinder K. Batra, Randall E. Brand, Joerg Ringel, Grit Faulmann, Matthias Lohr, Grish C. Varshney
  • Specific mucin expression as a marker for pancreatic cancer
    Patent number: 6576423
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: June 10, 2003
    Assignee: The Board of Regents of The University of Nebraska
    Inventors: Surinder K. Batra, Randall E. Brand, Jöerg Ringel, Grit Faulmann, Matthias Löhr, Grish C. Varshney
  • Encapsulated cells producing cytochrome P450
    Patent number: 6540995
    Abstract: The present invention relates to capsules encapsulating cytochrome P450 producing cells and cytochrome P450 producing retroviral packaging cells. Furthermore, the present invention relates to the treatment of cancer or any other relevant disease with said capsules and to the use of said capsules for the preparation of a pharmaceutical composition for said treatment.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: April 1, 2003
    Assignee: Bavarian Nordic Research Institute GmbH
    Inventors: Walter H. Günzburg, Peter Karle, Robert Saller, Brian Salmons, Matthias Löhr, Peter Müller
  • Specific mucin expression as a marker for pancreatic cancer
    Publication number: 20020150894
    Abstract: Methods are provided for the diagnosis of pancreatic cancer.
    Type: Application
    Filed: December 8, 2000
    Publication date: October 17, 2002
    Inventors: Surinder K. Batra, Randall E. Brand, Joerg Ringel, Grit Faulmann, Matthias Lohr, Grish C. Varshney