Patents by Inventor Matthias Lucke

Matthias Lucke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Articles comprising a silk polypeptide for antigen delivery
    Patent number: 11827678
    Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: November 28, 2023
    Assignees: Amsilk GmbH, Ludwig-Maximilians-Universitat Munchen, Universitat Bayreuth
    Inventors: Lin Romer, Ute Slotta, Julia Engert, Gerhard Winter, Matthias Lucke, Thomas Scheibel
  • Articles comprising a silk polypeptide for antigen delivery
    Patent number: 11667683
    Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: June 6, 2023
    Assignees: Amsilk GmbH, Ludwig-Maximilians-Universitat Munchen, Universitat Bayreuth
    Inventors: Lin Romer, Ute Slotta, Julia Engert, Gerhard Winter, Matthias Lucke, Thomas Scheibel
  • Pharmaceutical compositions comprising 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetate and sodium ions
    Publication number: 20230138444
    Abstract: The present invention relates to new stable pharmaceutical compositions containing 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid and sodium ions that are essentially free from complexing solubilizing agents, such as PEG, cyclodextrin, lysine, arginine, in particular HPBCD. The invention further relates to methods of preparation of said pharmaceutical compositions. The invention further relates to use of said pharmaceutical compositions in methods of treatment of and/or as a prophylactic for illnesses, particularly its use as an antiviral, preferably against cytomegaloviruses.
    Type: Application
    Filed: March 1, 2021
    Publication date: May 4, 2023
    Applicant: AIC246 AG & Co. KG
    Inventors: Helmut BUSCHMANN, Thomas GOLDNER, Jessica REDMER, Jordi Carles CERON BERTRAN, Andrea HAWE, Matthias LUCKE, Dorothea HOHMANN, Monica ROSA
  • Sodium 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetate and pharmaceutical compositions thereof
    Publication number: 20230095980
    Abstract: The present invention relates to new stable pharmaceutical compositions containing sodium 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)-phenyl]-4H-quinazolin-4-yl]acetate that are essentially free of complexing solubilizing agents, such as PEG, cyclodextrin, lysin, arginine, in particular HPBCD. The invention further relates to methods of preparation of said pharmaceutical compositions. The invention further relates to use of said pharmaceutical compositions in methods of treatment of and/or as a prophylactic for illnesses, particularly its use as an antiviral, preferably against cytomegaloviruses.
    Type: Application
    Filed: March 1, 2021
    Publication date: March 30, 2023
    Applicant: AIC246 AG & Co. KG
    Inventors: Helmut BUSCHMANN, Thomas GOLDNER, Jessica REDMER, Andrea HAWE, Matthias LUCKE, Dorothea HOHMANN, Monica ROSA
  • ARTICLES COMPRISING A SILK POLYPEPTIDE FOR ANTIGEN DELIVERY
    Publication number: 20210347832
    Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
    Type: Application
    Filed: July 23, 2021
    Publication date: November 11, 2021
    Inventors: Lin Romer, Ute Slotta, Julia Engert, Gerhard Winter, Matthias Lucke, Thomas Scheibel
  • ARTICLES COMPRISING A SILK POLYPEPTIDE FOR ANTIGEN DELIVERY
    Publication number: 20210332092
    Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
    Type: Application
    Filed: April 30, 2021
    Publication date: October 28, 2021
    Inventors: Lin ROMER, Ute SLOTTA, Julia ENGERT, Gerhard WINTER, Matthias LUCKE, Thomas SCHEIBEL
  • Articles comprising a silk polypeptide for antigen delivery
    Patent number: 11104708
    Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: August 31, 2021
    Assignees: Amsilk GmbH, Ludwig-Maximilians-Universitat Munchen, Universitat Bayreuth
    Inventors: Lin Romer, Ute Slotta, Julia Engert, Gerhard Winter, Matthias Lucke, Thomas Scheibel
  • ARTICLES COMPRISING A SILK POLYPEPTIDE FOR ANTIGEN DELIVERY
    Publication number: 20190161522
    Abstract: The present invention relates to a polypeptide comprising a silk polypeptide and an antigen. Further, the present invention relates to an article comprising the polypeptide. Furthermore, the present invention relates to a pharmaceutical composition comprising the article. In addition, the present invention relates to the article or pharmaceutical composition for use as a pharmaceutical, for inducing an immune response and/or for use in a prophylactic and/or therapeutic treatment of a disease.
    Type: Application
    Filed: June 13, 2017
    Publication date: May 30, 2019
    Inventors: Lin ROMER, Ute SLOTTA, Julia ENGERT, Gerhard Winter, Matthias Lucke, Thomas Scheibel