Patents by Inventor Maud H. W. Starmans

Maud H. W. Starmans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems, Devices and Methods for Constructing and Using a Biomarker
    Publication number: 20170218456
    Abstract: Methods, systems, devices and computer implemented methods of prognosing or classifying patients using a biomarker comprising a plurality of subnetwork modules are disclosed. In some embodiments, the method comprises determining an activity of a plurality of genes in a test sample of a patient, wherein the plurality of genes are associated with the plurality of subnetwork modules. An expression profile is constructed using the activity of the plurality of genes. The dysregulation of each of the plurality of subnetwork modules is determined by calculating a score proportional to a degree of dysregulation in each of the plurality of subnetwork modules from the expression profile. The patient is prognosed or classified by inputting each dysregulation score into a model for predicting patient outcomes for patients having a disease, and inputting a clinical indicator of the patient into the model, to obtain a risk associated with the disease.
    Type: Application
    Filed: July 23, 2015
    Publication date: August 3, 2017
    Inventors: John Bartlett, Paul Boutros, Victoria Sabine, Syed Haider, Maud H.W. Starmans, Cindy Qianli Yao, Jianxin Wang
  • Gene signature of early hypoxia to predict patient survival
    Patent number: 7960114
    Abstract: The present invention provides methods and compositions for predicting patient responses to cancer treatment using hypoxia gene signatures. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: June 14, 2011
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Renaud G. Seigneuric, Maud H. W. Starmans, Glenn Fung, Balaji Krishnapuram, Dimitry S. A. Nuyten, Arie van Erk, Michael Gaston Magagnin, Kasper M. Rouschop, Sriram Krishnan, R. Bharat Rao, Christoffel Theodorus Anthonius Evelo, Adrian Campbell Begg, Bradly G. Wouters, Philippe Lambin
  • Knowledge-Based Proliferation Signatures and Methods of Use
    Publication number: 20110059074
    Abstract: The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.
    Type: Application
    Filed: May 2, 2008
    Publication date: March 10, 2011
    Inventors: Maud H.W. Starmans, Balaji Krishnapuram, Ranand G. Seigneuric, Harald Steck, Dimitry S.A. Nuyten, Francesca Buffa, Adrian Lewellyn Harris, Bradly G. Wouters, Philippe Lambin, R. Bharat Rao, Sriram Krishnan
  • Gene Signature of Early Hypoxia to Predict Patient Survival
    Publication number: 20090130096
    Abstract: The present invention provides methods and compositions for predicting patient responses to cancer treatment using hypoxia gene signatures. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.
    Type: Application
    Filed: May 1, 2008
    Publication date: May 21, 2009
    Applicant: Siemens Medical Solutions USA, Inc.
    Inventors: Renaud G. Seigneuric, Maud H.W. Starmans, Glenn Fung, Balaji Krishnapuram, Dimitry S.A. Nuyten, Arie van Erk, Michael Gaston Magagnin, Kasper M. Rouschop, Sriram Krishnan, R. Bharat Rao, Christoffel Theodorus Anthonius Evelo, Adrian Campbell Begg, Bradly G. Wouters, Philippe Lambin
  • Knowledge-Based Proliferation Signatures and Methods of Use
    Publication number: 20080286273
    Abstract: The present invention provides methods and compositions for predicting patient responses to cancer treatment using a proliferation gene signature. These methods can comprise measuring in a biological sample from a patient the levels of gene expression of a group of the genes designated herein. The present invention also provides for microarrays that can detect expression from a group of genes.
    Type: Application
    Filed: May 1, 2008
    Publication date: November 20, 2008
    Applicant: Siemens Medical Solutions USA, Inc.
    Inventors: Maud H.W. Starmans, Balaji Krishnapuram, Renaud G. Seigneuric, Harald Steck, Dimitry S.A. Nuyten, Francesca Meteora Buffa, Adrian Lewellyn Harris, Bradly G. Wouters, Philippe Lambin, R. Bharat Rao, Sriram Krishnan