Abstract: The disclosure herein relates to various surgical methods for implanting a prosthesis in a patient. In particular, in some embodiments, a surgical method for preparing a knee of a patient to implant a customized knee prosthesis comprising: identifying epiphysary axis (2) of the patient tibia (1) by connecting the center of the tibial plateau with the center of the growth plate remnant on a preoperative planning; and performing a tibial cut (3) perpendicular to the epiphysary axis (2) of the tibia (1).

Abstract: The disclosure herein relates to various surgical methods for implanting a prosthesis in a patient. In particular, in some embodiments, a surgical method for preparing a knee of a patient to implant a customized knee prosthesis comprising: identifying epiphysary axis (2) of the patient tibia (1) by connecting the center of the tibial plateau with the center of the growth plate remnant on a preoperative planning; and performing a tibial cut (3) perpendicular to the epiphysary axis (2) of the tibia (1).

Abstract: The present invention relates to hydroxyapatite doped with Fe2+ ions and Fe3+ ions which partially substitute the calcium ions in the crystal lattice. The hydroxyapatite is characterized by an intrinsic magnetism of 0.05 to 8 emu/g, measured by applying a magnetic field of 34 Oe, due to the presence of magnetic nano-domains in the crystal lattice of HA, given the limited amount of magnetic secondary phases present, less than about 3% by volume. The intrinsically magnetic hydroxyapatite can be loaded with biological substances selected in the group consisting of proteins, genes, stem cells, growth factors, vascularization factors, active substances and drugs, under the control of an external magnetic field, as a carrier and release agent for biological substances or drugs, as a contrast agent in diagnostics or for bone or osteocartilage regeneration.

Abstract: The present invention relates to hydroxyapatite doped with Fe2+ ions and Fe3+ ions which partially substitute the calcium ions in the crystal lattice. The hydroxyapatite is characterized by an intrinsic magnetism of 0.05 to 8 emu/g, measured by applying a magnetic field of 34 Oe, due to the presence of magnetic nano-domains in the crystal lattice of HA, given the limited amount of magnetic secondary phases present, less than about 3% by volume. The intrinsically magnetic hydroxyapatite can be loaded with biological substances selected in the group consisting of proteins, genes, stem cells, growth factors, vascularization factors, active substances and drugs, under the control of an external magnetic field, as a carrier and release agent for biological substances or drugs, as a contrast agent in diagnostics or for bone or osteocartilage regeneration.

Abstract: The invention relates to use of a biological material containing cells supported on three-dimensional scaffolds containing at least one hyaluronic acid derivative for the preparation of grafts suitable for application by arthroscopy, and a kit of surgical instruments for implanting said biological material by arthroscopy.

Abstract: A pin for the anchoring of articular prostheses includes a connecting portion (4) with a prosthesis (2) and an engagement portion (5) in a hole obtained within a bone. The engagement portion (5) is at least partly deformable in a radial direction and in a resilient way, in order to allow the instantaneous blocking of the pin (1) in the hole and the primary fixing of the prosthesis (2) on the bone, so as to al low an easy primary fixing of the prosthesis by simply introducing with a pressure the connecting portion in the hole obtained within the bone itself.

Abstract: Use of a biological material containing cells supported on three-dimensional scaffolds containing at least one hyaluronic acid derivative for the preparation of grafts suitable for application by arthroscopy, and a kit of surgical instruments for implanting said biological material by arthroscopy.

Abstract: A tibial component for a replacement knee prosthesis comprising a tibial tray for connection to a suitably prepared tibia has a tray carrying fixed lateral and medial condylar bearing components. Only the medial component has a shock absorber located beneath it.