Patents by Inventor Maurizio DEL POETA

Maurizio DEL POETA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS
    Publication number: 20240124392
    Abstract: The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing
    Type: Application
    Filed: December 6, 2023
    Publication date: April 18, 2024
    Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Haramahalli, Yi Sun
  • Anti-fungals compounds targeting the synthesis of fungal sphingolipids
    Patent number: 11858880
    Abstract: The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing
    Type: Grant
    Filed: June 10, 2022
    Date of Patent: January 2, 2024
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Hanarahalli, Yi Sun
  • ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS
    Publication number: 20220394973
    Abstract: The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing
    Type: Application
    Filed: June 10, 2022
    Publication date: December 15, 2022
    Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Haranahalli, Yi Sun
  • ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS
    Publication number: 20220298103
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: April 20, 2022
    Publication date: September 22, 2022
    Applicant: The Research Foundation for The State University of New York
    Inventors: Maurizio Del Poeta, Visesato Mor
  • Anti-fungals compounds targeting the synthesis of fungal sphingolipids
    Patent number: 11414378
    Abstract: The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing a fungus.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: August 16, 2022
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Haranahalli, Yi Sun
  • Anti-fungals targeting the synthesis of fungal shingolipids
    Patent number: 11390580
    Abstract: The present invention provides a compound having the structure:
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: July 19, 2022
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Maurizio Del Poeta, Visesato Mor
  • ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS
    Publication number: 20200207705
    Abstract: The present invention provides a compound having the structure: and use of the compound for inhibiting the growth of or killing
    Type: Application
    Filed: June 15, 2018
    Publication date: July 2, 2020
    Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Iwao Ojima, Maurizio Del Poeta, Cristina Lazzarini, Krupanandan Haranahalli, Yi Sun
  • METHODS OF INHIBITING FUNGAL CERAMIDE SYNTHASE FOR TREATMENT OF CRYPTOCOCCUS NEOFORMANS INFECTION
    Publication number: 20200171132
    Abstract: The present invention provides a method of inhibiting the growth of a fungus comprising contacting the fungus with an effective amount of an inhibitor so as to thereby inhibit the growth of the fungus, wherein the inhibitor inhibits ceramide synthase 1 (Cer1) in the fungal cells of the fungus. The present invention also provides method of treating a subject afflicted with a fungal infection comprising administering to the subject an effective amount of an inhibitor so as to treat the subject afflicted with the fungal infection, wherein the inhibitor inhibits ceramide synthase 1 (Cer1) in the fungal cells of the fungus.
    Type: Application
    Filed: March 20, 2018
    Publication date: June 4, 2020
    Applicant: The Research Foundation for the State University of New York
    Inventors: Maurizio Del Poeta, Mansa Munshi, Krupanandan Haranahalli, Karen You, Iwao Ojima
  • ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS
    Publication number: 20200062698
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: June 24, 2019
    Publication date: February 27, 2020
    Applicant: The Research Foundation for the State University of New York
    Inventors: Maurizio Del Poeta, Visesato Mor
  • Vaccine compositions against pathogenic fungi and methods for use thereof
    Patent number: 10463722
    Abstract: The present disclosure provides compositions comprising mutant fungi include an inactive form of the sterylglucosidase enzyme. The present disclosure is also directed to vaccine based compositions, which include a mutant fungus that prohibit pathogenic fungal infection. This disclosure also provides methods for administering these compositions as a prophylaxis against fungal infection, as well as methods for isolating sterylglucosides that include the use of such mutant fungal compositions.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: November 5, 2019
    Assignee: The Research Foundation for The State University of New York
    Inventors: Maurizio Del Poeta, Antonella Rella
  • ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS
    Publication number: 20180141897
    Abstract: The present invention provides a compound having the structure:
    Type: Application
    Filed: December 7, 2015
    Publication date: May 24, 2018
    Applicant: The Research Foundation for the State University of New York
    Inventors: Maurizio Del Poeta, Visesato Mor
  • VACCINE COMPOSITIONS AGAINST PATHOGENIC FUNGI AND METHODS FOR USE THEREOF
    Publication number: 20180085442
    Abstract: The present disclosure provides compositions comprising mutant fungi include an inactive form of the sterylglucosidase enzyme. The present disclosure is also directed to vaccine based compositions, which include a mutant fungus that prohibit pathogenic fungal infection. This disclosure also provides methods for administering these compositions as a prophylaxis against fungal infection, as well as methods for isolating sterylglucosides that include the use of such mutant fungal compositions.
    Type: Application
    Filed: August 10, 2017
    Publication date: March 29, 2018
    Inventors: Maurizio DEL POETA, Antonella RELLA
  • FUNGAL GLUCOSYLCERAMIDE AS A VACCINE FOR FUNGAL INFECTIONS
    Publication number: 20170224790
    Abstract: The present invention features compositions that include a fungal glucosylceramide (GlcCer) purified from a non-pathogenic fungus (e.g., Candida utilis) and, optionally, an adjuvant. The invention also features methods of treating a patient who has a fungal disease and methods of preventing a fungal disease in a subject by administration of these compositions. Also within the scope of the invention are methods of formulating a fungal vaccine by: (a) providing a fungal glucosylceramide isolated from a non-pathogenic fungus; and (b) combining the fungal glucosylceramide with an adjuvant in a physiologically acceptable excipient.
    Type: Application
    Filed: September 30, 2015
    Publication date: August 10, 2017
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Maurizio DEL POETA, Visesato MOR, Toshiya SATO, Tomohiro NAKAGAWA