Patents by Inventor Mauro Panunzio

Mauro Panunzio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[B,F]azepine-5-carboxyamide
    Patent number: 7858778
    Abstract: A process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxyamide by hydrolysis of 5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine with peroxy compounds in alkali medium and in the presence of solvents.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: December 28, 2010
    Assignee: Farchemia S.R.L.
    Inventors: Mauro Panunzio, Eileen Campana, Gabriele Breviglieri
  • Process for the preparation of (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz (b,f)azepine-5-carboxamide
    Patent number: 7858780
    Abstract: (S)-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxyamide is prepared starting from racemic 5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine by phthaloylation, separation of the diastereomeric salts of the phthaloyl derivative with (S)-phenylethylamine, hydrolysis of the (S, S) salt to (S)-(+)-5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine and hydrolysis of the nitrile group of the latter to amido group, by treatment with peroxy compounds in alkali medium.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: December 28, 2010
    Assignee: Farchemia S.R.L.
    Inventors: Mauro Panunzio, Eileen Campana, Sabatino Pulcini, Gabriele Breviglieri
  • Process for the preparation of (S)-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz (B,F) azepine-5-carboxamide
    Publication number: 20090105472
    Abstract: (S)-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxyamide is prepared starting from racemic 5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine by phthaloylation, separation of the diastereomeric salts of the phthaloyl derivative with (S)-phenylethylamine, hydrolysis of the (S, S) salt to (S)-(+)-5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine and hydrolysis of the nitrile group of the latter to amido group, by treatment with peroxy compounds in alkali medium.
    Type: Application
    Filed: November 15, 2005
    Publication date: April 23, 2009
    Inventors: Mauro Panunzio, Eileen Campana, Sabatino Pulcini, Gabriele Breviglieri
  • Process For The Preparation Of 10,11-Dihydro-10-Hydroxy-5H-Dibenz[B,F]Azepine-5-Carboxyamide
    Publication number: 20080221320
    Abstract: A process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxyamide by hydrolysis of 5-cyano-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine with peroxy compounds in alkali medium and in the presence of solvents.
    Type: Application
    Filed: November 10, 2005
    Publication date: September 11, 2008
    Inventors: Mauro Panunzio, Eileen Campana, Gabriele Breviglieri
  • Process for the preparation of a thiazoline-azetidinone
    Patent number: 5721360
    Abstract: The present invention refers to process for the preparation of a tiazoline-azetidinone of formula I ##STR1## which comprises N-protecting in position 1 of (3S,4S)-3-phenylace tamido-4-acetoxy-azetidin-2-one, converting the product thus obtained into the corresponding thioamide and subsequently ciclyzing and deprotecting.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: February 24, 1998
    Assignee: Biochimica OPS Spa
    Inventors: Gianfranco Cainelli, Achille Umani Ronchi, Michele Contento, Mauro Panunzio, Sergio Sandri, Marco Da Col, Leone Dall'Asta
  • Process for the preparation of halogenated .beta.-lactam compounds
    Patent number: 5532353
    Abstract: There is described the preparation of halogenated .beta.-lactam derivatives by introduction of a chlorine atom in the 3-position of the cephem nucleus starting from a 3-sulfonyloxycephem. Such starting materials are reacted with a chlorine ions donor in a basic medium.
    Type: Grant
    Filed: May 10, 1993
    Date of Patent: July 2, 1996
    Assignee: Biochimica Opos SpA
    Inventors: Marco Da Col, Leone Dall'Asta, Irene Resta, Gianfranco Cainelli, Michele Contento, Mauro Panunzio, Achille Umani Ronchi
  • Steroidic 5.alpha.-reductase inhibitors
    Patent number: 4732897
    Abstract: The present invention relates to new 4-aza-17.beta.-substituted 5.alpha.-androstan-3-ones, to a process for their preparation, to pharmacological compostions containing them, and to the use of said compounds as inhibitors of androgen action by means of testosterone 5-reductase inhibition.
    Type: Grant
    Filed: February 3, 1986
    Date of Patent: March 22, 1988
    Assignees: Farmitalia Carlo Erba, S.p.A., Consiglio Nazionale Delle Ricerche
    Inventors: Gianfranco Cainelli, Giorgio Martelli, Mauro Panunzio, Giuseppe Spunta, Giuliano Nannini, Enrico di Salle