Abstract: A bulk acoustic wave (BAW) device comprises a layer stack including first and second electrodes, a first piezoelectric layer between the electrodes, and a second piezoelectric layer between the first piezoelectric layer and the second electrode. A polarization of a crystal structure of the second piezoelectric layer is opposite to a polarization of a crystal structure of the first piezoelectric layer to achieve higher order resonant frequencies in the BAW device by means other than merely thinning layers in the layer stack. In some examples, the BAW device is a two-terminal device and does not include a metal layer configured to be a third electrode. In some examples, the BAW device includes at least one intermediate layer between the first and second piezoelectric layers, and a total combined thickness of the at least one intermediate layer is less than 4% of a total thickness of the layer stack.

Abstract: A bulk acoustic wave resonator device comprises bottom and top electrodes (120, 360). A piezoelectric layer (355) sandwiched therebetween has a thickness in the active resonator area different from the thickness in the surrounding area. A method of manufacturing the device comprises a bonding of a piezoelectric wafer to a carrier wafer and splitting a portion of the piezoelectric wafer by an ion-cut technique. Different thicknesses of the piezoelectric layer in the active area and the surrounding area are achieved by implanting ions at different depths.

Abstract: The invention is based on the surprising finding of antibodies that bind to an immunoglobulin-like (Ig) domain of the extra cellular domain (ECD) of IGSF11 (VSIG3) can also inhibit the interaction between IGSF11 and IGSF11 receptors such as VSIR (VISTA), the inhibition of such interaction can provide products, compositions and methods for treating diseases using antigen binding proteins targeting an Ig domain of IGSF11-ECD, including those being inhibitors of IGSF11-interaction with VSIR. Also provided are methods of sensitising cells involved with a proliferative disorder against the cytotoxic effect of cell-mediated immune responses, and/or to kill such cells and/or methods for treating proliferative diseases, using an IGSF11 inhibitor such as an antibody binding to an Ig domain of IGSF11-ECD, as well as certain related aspects including detection, diagnostic and screening methods.

Abstract: The invention is based on the surprising finding of antibodies that bind to an immunoglobulin-like (Ig) domain of the extra cellular domain (ECD) of IGSF11 (VSIG3) can also inhibit the interaction between IGSF11 and IGSF11 receptors such as VSIR (VISTA), the inhibition of such interaction can sensitise tumour cells to anti-tumour immune responses. In particular, the invention provides products, compositions and methods for treating diseases using modulators of IGSF11, especially antigen binding proteins targeting an Ig domain of IGSF11-ECD, including those being inhibitors of IGSF11-interaction with VSIR. Also provided are methods of sensitising cells involved with a proliferative disorder against the cytotoxic effect of cell-mediated immune responses, and/or to kill such cells and/or methods for treating proliferative diseases, using an IGSF11 inhibitor such as an antibody binding to an Ig domain of IGSF11-ECD, as well as certain related aspects including detection, diagnostic and screening methods.

Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.

Abstract: The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.

Abstract: Disclosed herein is a method of automated noninvasive determining the sex of an embryo of a bird's egg (14) as well as a corresponding apparatus.

Abstract: Shown herein is a method of automated noninvasive determining the fertility of a bird's egg (14), comprising the following steps: conveying a plurality of bird eggs (14) sequentially or in parallel into an NMR apparatus (18), subjecting the bird eggs (14) to an NMR measurement, such as to generate a 3-D NMR image of at least a part of each of said eggs (14), said 3-D NMR image having a spatial resolution in at least one dimension of 1.0 mm or less, preferably of 0.

Abstract: Shown herein is a method of automated noninvasive determining the fertility of a bird's egg (14), comprising the following steps: conveying a plurality of bird eggs (14) sequentially or in parallel into an NMR apparatus (18), subjecting the bird eggs (14) to an NMR measurement, such as to generate a 3-D NMR image of at least a part of each of said eggs (14), said 3-D NMR image having a spatial resolution in at least one dimension of 1.0 mm or less, preferably of 0.

Abstract: Disclosed herein is a method of automated noninvasive determining the sex of an embryo of a bird's egg (14) as well as a corresponding apparatus.

Abstract: Separation of chlorosilane mixtures containing boron, arsenic, and/or phosphorus impurities is facilitated by a distillative separation using at least one divided column, with recycle streams to a first column being passed through an external absorbent for the impurities.

Abstract: Separation of chlorosilane mixtures containing boron, arsenic, and/or phosphorus impurities is facilitated by a distillative separation using at least one divided column, with recycle streams to a first column being passed through an external absorbent for the impurities.

Abstract: Separation of chlorosilane mixtures containing boron, arsenic, and/or phosphorus impurities is facilitated by a distillative separation using at least one divided column, with recycle streams to a first column being passed through an external absorbent for the impurities.

Abstract: Efficient distillative separation of an at least three component mixture containing high boiler, medium boiler and low boiler components is accomplished by interposing a column having a stripping section and a rectifying section separated from each other by a horizontal impermeable dividing wall between conventional distillation columns. High efficiency and low capital cost is achieved.

Abstract: A method and apparatus for distillative separation of a mixture comprising three or more components including at least one low boiler, at least one medium boiler, and at least one high boiler, the method comprising feeding the mixture of three or more components to a first distillation column, removing the at least one high boiler as a bottom fraction from the first distillation column, feeding a top fraction of the first distillation column to a second distillation column, removing the at least one medium boiler via a sidestream takeoff from the second distillation column, removing the at least one low boiler as a top fraction from the second distillation column, and feeding a bottom takeoff stream from the second distillation column to the first distillation column as a reflux, wherein the first and the second distillation columns have vertical dividing walls.

Abstract: Separation of chlorosilane mixtures containing boron, arsenic, and/or phosphorus impurities is facilitated by a distillative separation using at least one divided column, with recycle streams to a first column being passed through an external absorbent for the impurities.

Abstract: Efficient distillative separation of an at least three component mixture containing high boiler, medium boiler and low boiler components is accomplished by interposing a column having a stripping section and a rectifying section separated from each other by a horizontal impermeable dividing wall between conventional distillation columns. High efficiency and low capital cost is achieved.

Abstract: A method and apparatus for distillative separation of a mixture comprising three or more components including at least one low boiler, at least one medium boiler, and at least one high boiler, the method comprising feeding the mixture of three or more components to a first distillation column, removing the at least one high boiler as a bottom fraction from the first distillation column, feeding a top fraction of the first distillation column to a second distillation column, removing the at least one medium boiler via a sidestream takeoff from the second distillation column, removing the at least one low boiler as a top fraction from the second distillation column, and feeding a bottom takeoff stream from the second distillation column to the first distillation column as a reflux, wherein the first and the second distillation columns have vertical dividing walls.

Abstract: The present invention relates to an antibody fusion protein which specifically recognizes the VA, HN or F surface antigen of the New Castle Disease Virus (NDV), a surface molecule of a tumor-unspecific T cell or a surface molecule of a dendritic cell and an immunocytokine. Also encompassed by the present invention are polynucleotides encoding the aforementioned antibody fusion protein as well as tumor-unspecific key cells or dendritic cells bound by the antibody fusion protein. Moreover, the present invention relates to a method of treating a tumor in a subject comprising administering to the said subject the antibody fusion protein, the tumor-unspecific T cell, the dendritic cell or the polynucleotide of the invention. Preferably, the said tumor is a solid tumor.

Abstract: Storing events to enhance intrusion detection in networks is described. In one exemplary implementation, an event is received. The event includes a data section containing a set of strings each having an event field. A definition table is referenced to determine locations of event fields in the data section of the event. The event fields are stored in a database record corresponding to event field locations referenced from the definition table.