Patents by Inventor Maxine J. McCall

Maxine J. McCall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optimized minizymes and miniribozymes and uses thereof
    Patent number: 6277634
    Abstract: This invention is directed to improved catalytic compounds, minizymes and miniribozymes, capable of hybridizing with a target RNA to be cleaved. The minizymes and miniribozymes and compositions of the present invention may be used in vitro or in vivo. They may be used as diagnostic or therapeutic agents.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: August 21, 2001
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Maxine J. McCall, Philip Hendry, Trevor Lockett
  • Asymmetric hammerhead ribozymes
    Patent number: 6238917
    Abstract: This invention is directed to a compound having the formula: as defined in the detailed description. The compound may be covalently linked to a delivery agent. The invention also includes a composition which comprises the compound in association with an acceptable carrier. The invention also includes a method of cleaving an RNA target sequence which comprises contacting a target sequence with the compound as described above. Further, a method of treating a disease in man or animals associated with a particular RNA which comprises administrating to the man or animal the compound. Further, the invention also includes a diagnostic reagent which comprises the compound.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: May 29, 2001
    Assignee: Commonwealth Scientific Industrial Research Organizaion
    Inventors: Philip Hendry, Maxine J. McCall
  • Optimized minizymes and miniribozymes and uses thereof
    Patent number: 6004806
    Abstract: This invention is directed to improved catalytic compounds, minizymes and miniribozymes, capable of hybridizing with a target RNA to be cleaved. The minizymes and miniribozymes and compositions of the present invention may be used in vitro or in vivo. They may be used as diagnostic or therapeutic agents.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 21, 1999
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Maxine J. McCall, Philip Hendry, Trevor Lockett
  • Optimized minizymes and miniribozymes and uses thereof
    Patent number: 6001648
    Abstract: This invention is directed to improved catalytic compounds, minizymes and miniribozymes, capable of hybridizing with a target RNA to be cleaved. The minizymes and miniribozymes and compositions of the present invention may be used in vitro or in vivo. They may be used as diagnostic or therapeutic agents.
    Type: Grant
    Filed: December 18, 1995
    Date of Patent: December 14, 1999
    Assignee: Commonwealth Scientific and Industrial Research Organization
    Inventors: Maxine J. McCall, Philip Hendry, Trevor Lockett