Abstract: The invention relates to systems and methods for intracranial vessel access. In particular, a system including a co-axial combination of a steerable variable thickness microwire operatively supporting a tapered larger bore support and larger bore distal access catheter is described.

Abstract: The invention relates to systems and methods to improve perfusion flow and pressure during endovascular intervention. In particular, the invention relates to catheters that enable both antegrade and retrograde flow through the catheter during a recanalization procedure and specifically at the step in a procedure where a clot is being withdrawn. Additionally, the invention provides systems for supplying fluids and fluid compositions to improve nutrition to ischemic brain.

Abstract: Methods and apparatus for retrieving a blood clot are disclosed. The apparatus comprises an expandable wire frame for deployment using a push wire within a microcatheter. When deployed in the vicinity of a blood clot, the wire frame is configured to expand and trap the blood clot allowing the blood clot to be removed. The expandable wire frame is connected to the push wire at distal and proximal ends. One or more expansion stops define a minimum distance between the distal and proximal ends of the expandable wire frame and a point of maximum extension of the expandable wire frame. This may help the user to control the configuration of the apparatus as it is being used within the vascular system.

Abstract: The invention relates to systems and methods for intracranial vessel access. In particular, a system including a co-axial combination of a steerable variable thickness microwire operatively supporting a tapered larger bore support and larger bore distal access catheter is described. Methods of advancing the intracranial access system through the vasculature are also described.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: The invention relates to systems and methods to assist physicians in decision making for stroke patients. In particular the systems and methods can be used to assist physicians to decide on whether a patient with an acute ischemic stroke has a large vessel occlusion (LVO) and should be transferred from a community hospital to a larger hospital to undergo an endovascular thrombectomy procedure.

Abstract: An automated system and method for assisting in decision making for the treatment of stroke patients is provided, and specifically for assisting a physician whether the patient should be administered a drug or transferred to another hospital to undergo an endovascular thrombectomy procedure. A variety of factors are input into the system with limited human intervention and a tool automatically determines the probability of whether the patient will have a better outcome if transferred or not. The factors include clinical factors, imaging factors and time to transfer factors. The tool includes processes for automatically determining several imaging factors, including the determination of clot length, collateral blood flow, the presence of forward blood flow within and around the clot, and the clot permeability. The tool has capability to continuously update the treatment protocol and other output results using current clinical, health system or other relevant information or feedback.

Abstract: The invention relates to the treatment of aneurysms, and more particularly to intravascular devices and methods for the occlusion of an aneurysm. The device includes a first portion having an expandable and compressible mesh having dimensions for insertion into and expansion against the wall of an aneurysm and a second disk portion having a flexible, collapsible mesh operatively connected to an outer surface of the first portion and having dimensions for covering an outside of the neck opening. The combination of the first portion and second disk portion have a combined resilient flexibility to effectively bias the second disk portion against the neck opening in a substantially flat manner when the first portion is engaged within the aneurysm.

Abstract: The invention describes systems and methods for retrieving blood clots (thrombi) from patients undergoing endovascular/neurointervention procedures following ischemic stroke are described. More specifically, blood clot retrieval devices for deployment into a patient's vasculature from a catheter that are effective in ensnaring and removing fibrin rich thrombi are described as well as methods of utilizing these devices.

Abstract: The invention relates to systems and methods for diagnosing strokes. In particular, systems and methods for acquiring timely patient status information are described that enable a physician to make diagnostic and treatment decisions relating to strokes. The systems and methods enable the efficient and quantitative assessment of arterial collaterals within the brain for aiding these decisions in the case of ischemic strokes.

Abstract: The invention relates to systems and methods for intracranial venous vessel access and a system for treatment of dural sinus thrombosis. In particular, a system including a co-axial combination of a steerable variable thickness microwire operatively supporting a tapered larger bore support and larger bore distal access catheter is described. Methods of advancing the intracranial access system through the venous vasculature are also described.

Abstract: Systems and methods for preparing and completing surgical and medical procedures. In particular, kits are provided for improving preparation and completion time for a medical or surgical procedure in which the kit includes modularized compartments containing sterilized medical or surgical equipment and wherein the medical or surgical equipment is organized and/or ordered within the kit to generally correspond to the sequence of steps of the medical or surgical procedure. The kit is particularly applicable to recanalization procedures for stroke patients as well as revascularization procedures for acute myocardial infarction patients where a kit enables faster preparation and completion of these procedures.

Abstract: Microcatheters having enlarged distal ends with distally decreasing tapered portions are disclosed. These microcatheters can be used for various treatments within a vessel, such as treatment of a vasospasm and delivery of a liquid embolic material.

Abstract: An obstruction removal device is described, having one or more engaging members which can engage portions of the clot. The one or more engaging members have a collapsed, delivery state, and an expanded, deployed state which in some embodiments can be locked to maintain its fixed configuration.

Abstract: The invention relates to systems and methods enabling a personalized solution for allowing more efficient access to the carotid artery (or vertebral arteries) in patients needing endovascular/neurointervention procedures using catheter systems.

Abstract: Resource feature transfer is described. In one or more embodiments, information is collected about interaction of an unauthenticated user of a computing device with a resource, such as content (e.g., a web page) or an application. The information may identify the user, a device or application used to interact with the resource, and so on. This information is communicated to an identity management service (IMS) to determine features to make accessible to the unauthenticated user when interacting with the resource. During the interaction, the user initiates authentication to a corresponding user profile. To achieve a consistent user experience, the features made accessible to the user when unauthenticated are transferred so they are also accessible when authenticated. To do this, authentication information is communicated to the IMS with a token indicating the features determined for the unauthenticated user. The IMS then merges these features with features indicated by the user profile.

Abstract: A computer implemented method and apparatus for version independent Point of Sale Activation (POSA) product download. The method comprises accessing a database, wherein the database comprises a plurality of entries associated with a plurality of Point of Sale Activation (POSA) cards available for purchase at a retail store; retrieving, from the database, a plurality of entries associated with a previous version of a software product, wherein the previous version of the software product has not been redeemed; generating a serial number for each retrieved entry, wherein each serial number is associated with a current version of the software product; and updating, in the database, each retrieved entry with the generated serial number.

Abstract: Resource feature transfer is described. In one or more embodiments, information is collected about interaction of an unauthenticated user of a computing device with a resource, such as content (e.g., a web page) or an application. The information may identify the user, a device or application used to interact with the resource, and so on. This information is communicated to an identity management service (IMS) to determine features to make accessible to the unauthenticated user when interacting with the resource. During the interaction, the user initiates authentication to a corresponding user profile. To achieve a consistent user experience, the features made accessible to the user when unauthenticated are transferred so they are also accessible when authenticated. To do this, authentication information is communicated to the IMS with a token indicating the features determined for the unauthenticated user. The IMS then merges these features with features indicated by the user profile.

Abstract: Systems and methods for preparing and completing surgical and medical procedures. In particular, kits are provided for improving preparation and completion time for a medical or surgical procedure in which the kit includes modularized compartments containing sterilized medical or surgical equipment and wherein the medical or surgical equipment is organized and/or ordered within the kit to generally correspond to the sequence of steps of the medical or surgical procedure. The kit is particularly applicable to recanalization procedures for stroke patients as well as revascularization procedures for acute myocardial infarction patients where a kit enables faster preparation and completion of these procedures.

Abstract: The invention relates to systems and methods for obtaining particular medical data from a patient and organizing and presenting medical data for the objective of improving workflow and decision making during a medical emergency. More specifically, the systems and methods enable a first party to enter specific medical information about the patient wherein the system organizes the medical data in terms of relevancy for potential emergency situations and displays that relevant medical information to another party when that another party gains access to the system when a medical emergency is occurring.