Abstract: Provided herein are novel crystalline forms of a crystalline compound of Formula (I), which modulates the ORL-1 receptor. The crystalline compounds of Formula (I), compositions thereof, and methods of using thereof that are described herein are particularly useful for treatment, prevention, and management of several sleep disorders.

Abstract: There is provided a pinching tool capable of reliably pinching an object by a pair of pinching teeth each having a continuous mountain-valley shape and accurately performing a secondary operation on the object pinched between the pinching teeth. A first arm 1 and a second arm 2 each of which has a jaw 4 arranged on the front end and a grip 5 arranged on the rear end side are coupled in an X shape by coupling bosses 6 arranged on the arms 1, 2 adjacent to the jaws 4 and a coupling shaft 3. Lateral pinching teeth 11 are formed on front parts of opposed surfaces of the pair of jaws 4. Each of the lateral pinching teeth 11 includes a plurality of lateral rib teeth 17 which extend in a direction intersecting a tool central axis 8 and are continuous in a mountain-valley shape.

Abstract: A method of manufacturing a semiconductor device includes cutting a part of a resin insulating layer formed on a surface of a semiconductor substrate with a cutting tool. The cutting the part of the resin insulating layer includes cutting a portion of the resin insulating layer that has a surface on which a metal layer is disposed. The cutting the portion of the resin insulating layer is performed in such a manner that, in a stress distribution inside the resin insulating layer along an edge portion of the cutting tool and a peripheral portion of the edge portion, a width at 90% of a maximum value is not more than 1.3 ?m.

Abstract: In a method of manufacturing a semiconductor device, an electrode layer is formed on a surface of a semiconductor substrate, and a resin insulation layer is formed on the surface of the semiconductor substrate so that the electrode layer can be covered with the resin insulation layer. A tapered hole is formed in the insulation layer by using a tool bit having a rake angle of zero or a negative value. The tapered hole has an opening defined by the insulation layer, a bottom defined by the electrode layer, and a side wall connecting the opening to the bottom.