Abstract: The invention provides an aqueous ophthalmic composition, containing a beta blocker such as timolol, carteolol or the like, and a sugar alcohol such as mannitol, sorbitol or the like, optionally together with boric acid. The composition of the invention can improve the corneal permeability of a drug, so that the dose of the drug can be lowered, for example by decreasing the frequency of application to the eyes. It is therefore expected that the risk of systemic side effects which may be induced by the application of the beta blocker to the eyes, including cardiotoxicity or respiratory toxicity can be reduced. The decrease in the frequency of application of ophthalmic solution can favorably improve the QOL and prevent the decrease of therapeutic effect which may be caused by missing the application to the eyes.

Abstract: A PTC device has two electrodes affixed to opposed surfaces. The electrodes consist of a metal foil having a conductive layer on their surfaces that contact the PTC material. The conductive layer has a thermal coefficient of expansion intermediate between the thermal coefficients of expansion of the metal foil and the PTC material. The intermediate value of the thermal coefficient of expansion of the conductive layer prevents peeling of the electrodes off the PTC element due to the variation of the temperature of the PTC device resulting from repeated voltage applications. In addition, improved adhesion of the electrodes to the PTC material reduces resistance changes after repeated temperature cycling.

Abstract: A product having a positive temperature coefficient of resistance is formed by etching a carbon black at an elevated temperature to remove less crystalline portions and thereby to increase the specific surface area of the carbon black. The resulting carbon black is called porous carbon black. The porous carbon black is blended with a crystalline polymer to form a product having the desired positive temperature coefficient of resistance. Production of a material suitable for use as a resettable fuse is described.