Patents by Inventor Mayur Devjibhai Khunt
Mayur Devjibhai Khunt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9512060Abstract: Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibenzoyl-(D)-tartrate salt, a malate salt, a maleate salt, or a salicylate salt.Type: GrantFiled: February 5, 2015Date of Patent: December 6, 2016Assignee: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Vikas Daulatrao Ahirao, Nitin Sharadchandra Pradhan
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Publication number: 20150299101Abstract: Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibenzoyl-(D)-tartrate salt, a malate salt, a maleate salt, or a salicylate salt.Type: ApplicationFiled: February 5, 2015Publication date: October 22, 2015Inventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Vikas Daulatrao Ahirao, Nitin Sharadchandra Pradhan
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Patent number: 8981154Abstract: Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibenzoyl-(D)-tartrate salt, a malate salt, a maleate salt, or a salicylate salt.Type: GrantFiled: September 11, 2012Date of Patent: March 17, 2015Assignee: Actavis Group PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Nitin Sharadchandra Pradhan, Depashri Vikas Ahirao
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Publication number: 20130096346Abstract: Provided herein is an improved and industrially advantageous optical resolution method for resolving (2R,3R)/(2S,3S)-1-dimethylamino-3-(3-methoxyphenyl)-2-methylpentan-3-ol, and use thereof for the preparation of tapentadol or a pharmaceutically acceptable salt thereof. Provided further herein is an improved and industrially advantageous optical resolution method for resolving (2R,3R)/(2S,3S)-[3-(3-methoxyphenyl)-2-methylpentyl]-dimethylamine, and use thereof for the preparation of tapentadol or a pharmaceutically acceptable salt thereof. Disclosed also herein is an improved, commercially viable and industrially advantageous process for the preparation of tapentadol or a pharmaceutically acceptable salt thereof in high yield and purity.Type: ApplicationFiled: March 1, 2011Publication date: April 18, 2013Applicant: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Nitin Sharadchandra Pradhan
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Publication number: 20130096347Abstract: Provided herein is a novel, commercially viable and industrially advantageous process for the preparation of 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol (Tapentadol), or a pharmaceutically acceptable salt thereof, and its intermediates, in high yield and purity. Provided also herein are novel solid state forms of tapentadol intermediates and processes for their preparation thereof. Provided further herein is a purification process for preparing highly pure tapentadol hydrochloride.Type: ApplicationFiled: April 4, 2011Publication date: April 18, 2013Applicant: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Nilesh Sudhir Patil, Haushabhau Shivaji Pagire, Nitin Sharadchandra Pradhan
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Publication number: 20130090314Abstract: Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibenzoyl-(D)-tartrate salt, a malate salt, a maleate salt, or a salicylate salt.Type: ApplicationFiled: September 11, 2012Publication date: April 11, 2013Applicant: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Nitin Sharadchandra Pradhan, Depashri Vikas Ahirao
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Patent number: 8288592Abstract: Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibenzoyl-(D)-tartrate salt, a malate salt, a maleate salt, or a salicylate salt.Type: GrantFiled: September 21, 2010Date of Patent: October 16, 2012Assignee: Actavis Group PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Vikas Daulatrao Ahirao, Depashri Vikas Ahirao, legal representative, Nitin Sharadchandra Pradhan
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Publication number: 20110313176Abstract: Provided herein are convenient, industrially advantageous and environmentally friendly processes for the preparation of (?)-(S)-5-hydroxy-2-[N-n-propyl-N-2-(2-thienyl)ethylamino]tetralin (rotigotine) or a pharmaceutically acceptable salt thereof. Provided further herein is a highly pure rotigotine or a pharmaceutically acceptable salt thereof substantially free of impurities, processes for the preparation thereof, and pharmaceutical compositions comprising highly pure rotigotine or a pharmaceutically acceptable salt thereof substantially free of impurities.Type: ApplicationFiled: December 22, 2009Publication date: December 22, 2011Applicant: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai Khunt, Shrikant Varma, Nilesh Sudhir Patil, Haushabhau Shivaji Pagire, Nitin Sharadchandra Pradhan
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Publication number: 20110300218Abstract: Provided herein are solid state forms of ranolazine salts. Also provided is a stable amorphous form of ranolazine hydrochloride having a water content of less than about 0.5% by weight. Further provided are amorphous co-precipitates of ranolazine or a pharmaceutically acceptable salt thereof with povidone. Processes for the preparation of ranolazine forms, pharmaceutical compositions, and methods of treating thereof are also included. The solid state forms of ranolazine salts are useful for preparing ranolazine in high purity.Type: ApplicationFiled: September 8, 2009Publication date: December 8, 2011Applicant: ACTAVIS GROUP PTC EHFInventors: Venkata Subbarao Athukuri, Saidugari Swamy, Mayur Devjibhai Khunt, Nitin Sharadehandra Pradhan
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Publication number: 20110245536Abstract: Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of pregabalin in high yield and purity. The present invention also provides a process for the purification of (S)-pregabalin.Type: ApplicationFiled: June 1, 2009Publication date: October 6, 2011Applicant: ACTAVIS GROUP PTC EHFInventors: Vikas Daulatrao Ahirrao, Depashri Vikas Ahirrao, Chandra Prakash Narani, Sandipan Prabhurao Bondge, Mayur Devjibhai Khunt, Nitin Sharadchandra Pradhan, Jon Valgeirsson
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Publication number: 20110223213Abstract: Provided herein is an impurity of ranolazine, 1-[4-[2-hydroxy-3-(2-methoxy-phenoxy)-propyl]-piperazin-1-yl]-3-(2-methoxy-phenoxy)-propan-2-ol (dimer impurity-3), and process for preparing and isolating thereof. Provided further herein is a highly pure ranolazine or a pharmaceutically acceptable salt thereof substantially free of dimer impurity-3, process for the preparation, and pharmaceutical compositions comprising highly pure ranolazine or a pharmaceutically acceptable salt thereof substantially free of dimer impurity-3.Type: ApplicationFiled: October 13, 2009Publication date: September 15, 2011Applicant: ACTAVIS GROUP PTC EHFInventors: Venkata Subbarao Athukuri, Saidugari Swamy, Chandraprakash Narani, Mayur Devjibhai Khunt, Nitin Sharadchandra Pradhan
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Patent number: 7947699Abstract: Described is a highly stable amorphous form of imatinib mesylate having a water content of less than 0.5 percent by weight, based on the total weight of the amorphous imatinib mesylate, (anhydrous amorphous imatinib mesylate), a process for preparation thereof, and pharmaceutical compositions.Type: GrantFiled: January 9, 2009Date of Patent: May 24, 2011Assignee: Actavis Group PTC EHFInventors: Mayur Devjibhai Khunt, Nilesh Sudhir Patil, Haushabhau Shivaji Pagire, Nitin Sharadchandra Pradhan, Jon Valgeirsson
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Publication number: 20110071120Abstract: Provided herein are novel solid state forms of tapentadol salts, process for their preparation, pharmaceutical compositions, and method of treating thereof. The tapentadol salts include an L-(?)-camphorsulfonate salt, a dibenzoyl-(L)-tartrate salt, a dibenzoyl-(D)-tartrate salt, a malate salt, a maleate salt, or a salicylate salt.Type: ApplicationFiled: September 21, 2010Publication date: March 24, 2011Applicant: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai Khunt, Sandipan Prabhurao Bondge, Vikas Daulatrao Ahirao, Depashri Vikas Ahirao, Nitin Sharadchandra Pradhan
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Publication number: 20100330130Abstract: Provided herein are impurities of imatinib, N-(2-Methyl-5-methylamino-phenyl)-N-(4-pyridin-3-yl-pyrimidin-2-yl)-formamide (formamide impurity) and 4-[4-(Imidazole-1-carbonyl)-piperazin-1-ylmethyl]-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide (carbonylimidazole impurity), and processes for the preparation and isolation thereof. Provided further herein is a highly pure imatinib or a pharmaceutically acceptable salt thereof substantially free of formamide and carbonylimidazole impurities, processes for the preparation thereof, and pharmaceutical compositions comprising highly pure imatinib or a pharmaceutically acceptable salt thereof substantially free of impurities. Disclosed also herein is a process for preparing substantially pure ?-form of imatinib mesylate.Type: ApplicationFiled: May 18, 2010Publication date: December 30, 2010Applicant: ACTAVIS GROUP PTC EHFInventors: Mayur Devjibhai KHUNT, Nilesh Sudhir PATIL, Haushabhau Shivaji PAGIRE, Nitin Sharadchandra PRADHAN
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Publication number: 20100272815Abstract: Disclosed herein is a novel and stable amorphous form of tapentadol hydrochloride, a process for the preparation, pharmaceutical compositions, and a method of treating thereof. Disclosed also herein is a stable amorphous co-precipitate of tapentadol hydrochloride with pharmaceutically acceptable excipients, a method for the preparation, pharmaceutical compositions, and a method of treating thereof. Advantageously, the amorphous co-precipitates of tapentadol hydrochloride have improved physiochemical characteristics that assist in the effective bioavailability.Type: ApplicationFiled: April 28, 2010Publication date: October 28, 2010Inventors: Mayur Devjibhai KHUNT, Sandipan Prabhurao BONDGE, Vikas Daulatrao Ahirao, Nitin Sharadchandra Pradhan, Depashri Vikas Ahirao
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Publication number: 20090202647Abstract: Disclosed herein are solid state forms, amorphous and crystalline forms, of racemic rotigotine having high purity, adequate stability, good flowability and good dissolution properties, a process for preparation, and pharmaceutical compositions comprising amorphous racemic rotigotine.Type: ApplicationFiled: February 11, 2009Publication date: August 13, 2009Inventors: Mayur Devjibhai Khunt, Nilesh Sudhir Patil, Nitin Sharadchandra Pradhan, Jon Valgeirsson
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Publication number: 20090181977Abstract: Described is a highly stable amorphous form of imatinib mesylate having a water content of less than 0.5 percent by weight, based on the total weight of the amorphous imatinib mesylate, (anhydrous amorphous imatinib mesylate), a process for preparation thereof, and pharmaceutical compositions.Type: ApplicationFiled: January 9, 2009Publication date: July 16, 2009Applicant: Actavis Group PTC ehfInventors: Mayur Devjibhai Khunt, Nilesh Sudhir Patil, Haushabhau Shivaji Pagire, Nitin Sharadchandra Pradhan, Jon Valgeirsson
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Publication number: 20080287481Abstract: The present application provides a process for the preparation of mixture of polymorphic Form I and Form II of desloratadine in any desired ratio.Type: ApplicationFiled: September 7, 2007Publication date: November 20, 2008Inventors: Mayur Devjibhai Khunt, Srinivasa Reddy Madduri
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Publication number: 20080281099Abstract: The invention relates to processes for the purification of valacyclovir hydrochloride and intermediates thereof.Type: ApplicationFiled: May 7, 2008Publication date: November 13, 2008Inventors: Mayur Devjibhai Khunt, Bojja Ramachandra Reddy, Keshava Naveen Kumar Reddy, Vedantham Ravindra, Sripathi Somaiah, Sundaraneedi Veera Madhavi
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Publication number: 20080194823Abstract: A process for preparing loratadine crystalline polymorphic Form I.Type: ApplicationFiled: April 4, 2007Publication date: August 14, 2008Inventors: Mayur Devjibhai Khunt, Naveen Kumar Reddy Keshava, Srinivasa Reddy Madduri, Somaiah S. Sripathi, Sudhakar Valluri