Patents by Inventor Meenakshi SUDHAKARAN

Meenakshi SUDHAKARAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid and efficient de-glycosylation of glycoproteins
    Patent number: 11530403
    Abstract: The present invention discloses rapid and cost-effective method of de-glycosyation of a glycoprotein, wherein, glycoprotein is combined with anionic surfactant and reducing agent and non-ionic surfactant in order to obtain stable denatured glycoprotein. An endoglycosidase is further added to denatured glycoprotein to cleave N-linked glycans in order to obtain de-glycosylated protein. A rapid tool for assessing the protein conformation by partial de-glycosylation is also presented wherein the partial de-glycosylated protein is analysed using capillary electrophoresis (CE-SDS).
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: December 20, 2022
    Assignee: BIOCON LIMITED
    Inventors: Anushikha Thakur, Seija Rohil, Shrivardhan Patil, Meenakshi Sudhakaran, Laxmi Adhikary
  • RAPID AND EFFICIENT DE-GLYCOSYLATION OF GLYCOPROTEINS
    Publication number: 20200291377
    Abstract: The present invention discloses rapid and cost-effective method of de-glycosyation of a glycoprotein, wherein, glycoprotein is combined with anionic surfactant and reducing agent and non-ionic surfactant in order to obtain stable denatured glycoprotein. An endoglycosidase is further added to denatured glycoprotein to cleave N-linked glycans in order to obtain de-glycosylated protein. A rapid tool for assessing the protein conformation by partial de-glycosylation is also presented wherein the partial de-glycosylated protein is analysed using capillary electrophoresis (CE-SDS).
    Type: Application
    Filed: November 17, 2017
    Publication date: September 17, 2020
    Inventors: Anushikha THAKUR, Seija ROHIL, Shrivardhan PATIL, Meenakshi SUDHAKARAN, Laxmi ADHIKARY