Patents by Inventor Megan Foley

Megan Foley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteasome activity enhancing compounds
    Patent number: 11958873
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: April 16, 2024
    Assignee: Kineta, Inc.
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein, Bradley Tait
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20240116894
    Abstract: The present invention is directed to compounds that inhibit Usp14, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: July 12, 2023
    Publication date: April 11, 2024
    Inventors: Matthew Cullen, Sheila Hauck, Megan Foley, Bradley Tait, Markus Haeberlein
  • Proteasome activity enhancing compounds
    Patent number: 11746098
    Abstract: The present invention is directed to compounds that inhibit Usp14, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: September 5, 2023
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Matthew Cullen, Sheila Hauck, Megan Foley, Bradley Tait, Markus Haeberlein
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20230242557
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: December 17, 2021
    Publication date: August 3, 2023
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein, Bradley Tait
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20220298181
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: December 17, 2021
    Publication date: September 22, 2022
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein, Bradley Tait
  • Proteasome activity enhancing compounds
    Patent number: 11242361
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: February 8, 2022
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein, Bradley Tait
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20210188802
    Abstract: The present invention is directed to compounds that inhibit Usp14, compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: December 23, 2020
    Publication date: June 24, 2021
    Inventors: Matthew Cullen, Sheila Hauck, Megan Foley, Bradley Tait, Markus Haeberlein
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20200308198
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: June 15, 2020
    Publication date: October 1, 2020
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein, Bradley Tait
  • PROTEOSTASIS REGULATORS
    Publication number: 20200299270
    Abstract: The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
    Type: Application
    Filed: November 21, 2019
    Publication date: September 24, 2020
    Inventors: Megan Foley, Bradley Tait, Matthew Cullen
  • Proteostasis regulators
    Patent number: 10532996
    Abstract: The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: January 14, 2020
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Megan Foley, Bradley Tait, Matthew Cullen
  • Multi-carrier, zonal weaving system, method, and material
    Patent number: 10145037
    Abstract: A multi-carrier, zonal weaving system and method of manufacturing a zonal woven material is provided. The multi-carrier system includes a first weft yarn, a second weft yarn, and one or more intermediate warp yarns for wrapping by the first and second weft yarns. The zonal weaving method includes receiving a first weft yarn from a first origin via a first shed, wrapping it around one or more zonal warp yarns, and returned to the first weft origin after the first shed upper and lower yarns are exchanged. In further aspects, a second weft yarn is received from a second weft origin via a second shed, wrapped around the same intermediate, zonal warp yarns, and returned to the second weft origin after exchange of the second shed yarns. In one aspect, the first and second weft yarns are interlocked during wrapping of the common warp yarns.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: December 4, 2018
    Assignee: NIKE, Inc.
    Inventors: Carrie L. Davis, Megan Foley, William C. McFarland, II
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20180282352
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: December 4, 2017
    Publication date: October 4, 2018
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein
  • WOVEN FOOTWEAR UPPER
    Publication number: 20180135213
    Abstract: Aspects of the present invention relate to a dynamic woven material that is capable of undergoing a dimensional change in response to an external stimulus. The dynamic woven material comprises a plurality of discrete woven cells, where each woven cell comprises a reactive region and a non-reactive region. The reactive region changes from a first physical state to a second physical state when the woven material is exposed to the external stimulus. The woven material may be formed with zonal stretch properties by varying the areas occupied by the reactive region and the non-reactive region in each woven cell. For example, the bigger the area occupied by the reactive region in the woven cells in a particular zone of the dynamic woven material, the higher the level of stretch in the particular zone may be. Exemplary products manufactured from the dynamic woven material include, for example, articles of footwear.
    Type: Application
    Filed: November 10, 2017
    Publication date: May 17, 2018
    Inventors: THOMAS G. BELL, ROBERT M. BRUCE, YUCHUNG KEVIN CHEN, YOON JEONG CHOI, ADAM R. FARMER, MEGAN FOLEY, OLIVER MCLACHIAN, JAMES Y. YOO
  • Proteasome activity enhancing compounds
    Patent number: 9850262
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: December 26, 2017
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein
  • PROTEOSTASIS REGULATORS
    Publication number: 20170247355
    Abstract: The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
    Type: Application
    Filed: January 10, 2017
    Publication date: August 31, 2017
    Inventors: Megan Foley, Bradley Tait, Matthew Cullen
  • MULTI-CARRIER, ZONAL WEAVING SYSTEM, METHOD, AND MATERIAL
    Publication number: 20170218541
    Abstract: A multi-carrier, zonal weaving system and method of manufacturing a zonal woven material is provided. The multi-carrier system includes a first weft yarn, a second weft yarn, and one or more intermediate warp yarns for wrapping by the first and second weft yarns. The zonal weaving method includes receiving a first weft yarn from a first origin via a first shed, wrapping it around one or more zonal warp yarns, and returned to the first weft origin after the first shed upper and lower yarns are exchanged. In further aspects, a second weft yarn is received from a second weft origin via a second shed, wrapped around the same intermediate, zonal warp yarns, and returned to the second weft origin after exchange of the second shed yarns. In one aspect, the first and second weft yarns are interlocked during wrapping of the common warp yarns.
    Type: Application
    Filed: January 26, 2017
    Publication date: August 3, 2017
    Inventors: Carrie L. Davis, Megan Foley, William C. McFarland, II
  • Proteostasis regulators
    Patent number: 9556166
    Abstract: The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: January 31, 2017
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Megan Foley, Bradley Tait, Matthew Cullen
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20160333031
    Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: May 12, 2016
    Publication date: November 17, 2016
    Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein
  • Proteasome activity modulating compounds
    Patent number: 9399647
    Abstract: The present invention is directed to compounds having the Formula (I), (Ia) or (Ib), compositions thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: July 26, 2016
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Robert J. Chambers, Megan Foley, Bradley Tait
  • PROTEASOME ACTIVITY ENHANCING COMPOUNDS
    Publication number: 20150166567
    Abstract: The present invention is directed to compounds having the Formula (I), (Ia) or (Ib), compositions thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis.
    Type: Application
    Filed: July 17, 2014
    Publication date: June 18, 2015
    Inventors: Robert J. Chambers, Megan Foley, Bradley Tait