Patents by Inventor Megan Schwarz

Megan Schwarz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) DEGRADATION / DISRUPTION COMPOUNDS AND METHODS OF USE
    Publication number: 20210261538
    Abstract: Disclosed are protein arginine methyltransferase 5 (PRMT5) degradation/disruption compounds including a PRMT5 ligand, a degradation/disruption tag and a linker, and methods for use of such compounds in the treatment of PRMT5-mediated diseases. The PRMT5 degraders disclosed herein offer a novel mechanism for treating PRMT5-mediated diseases compared to small molecule inhibitors of PRMT5 activity.
    Type: Application
    Filed: February 22, 2019
    Publication date: August 26, 2021
    Inventors: Jian Jin, Jing Liu, Yudao Shen, Ernesto Guccione, Martin Walsh, Almudena Bosch, Megan Schwarz