Patents by Inventor Mehmet Candas
Mehmet Candas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090203049Abstract: Recombinant materials for the production of ? integrin protein characteristic of Manduca sexta are useful for screening pesticides for this moth.Type: ApplicationFiled: January 20, 2009Publication date: August 13, 2009Inventors: Lee A. BULLA, Mehmet Candas
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Patent number: 7349811Abstract: The present invention provides a system, method and apparatus for targeting gene sequences having one or more phenotypic characteristics using a computer. One or more phenotypic characteristics are selected. A gene sequence is then selected that is known to have the selected phenotypic characteristics. In addition, one or more databases containing cataloged gene sequences are selected. The selected gene sequence is compared to the cataloged gene sequences, and any cataloged gene sequences that contain a portion of the selected gene sequence are extracted. The selected gene sequence is aligned to each portion of the extracted gene sequence and the extracted gene sequences are prioritized based on the alignment of the selected gene sequence. At least one of the prioritized gene sequences is selected based on one or more phenotypic criteria. Finally, one or more degenerate primers are designed to target the selected-prioritized gene sequences.Type: GrantFiled: April 26, 2005Date of Patent: March 25, 2008Assignee: Board of Regents, The University of Texas SystemInventors: Lee A. Bulla, Jr., Mehmet Candas
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Publication number: 20070219269Abstract: A bacterial protein which converts 2-methyl citrate to 2-methyl isocitrate is a previously unknown target for antibacterial agents. The protein of this activity is associated with mucoid bacteria and inhibitors of production or activity of this protein in combination with propionic acid mitigate the virulence of these bacteria.Type: ApplicationFiled: February 27, 2007Publication date: September 20, 2007Inventors: Mehmet Candas, Lee Bulla
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Patent number: 7183100Abstract: A bacterial protein which converts 2-methyl citrate to 2-methyl isocitrate is a previously unknown target for antibacterial agents. The protein of this activity is associated with mucoid bacteria and inhibitors of production or activity of this protein in combination with propionic acid mitigate the virulence of these bacteria.Type: GrantFiled: May 19, 2003Date of Patent: February 27, 2007Assignee: Biological Targets, Inc.Inventors: Mehmet Candas, Lee A. Bulla
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Patent number: 7094554Abstract: A cDNA encoding a 200 kD receptor, BT-R2, from the pink boll worm, Pectinophora gossypiella, that binds specifically to a Bacillus thuringiensis toxin has been cloned, sequenced and characterized. The minimum toxin binding fragment has been identified. The BT-R2 cDNA permits the analysis of receptors in pink boll worm and other insects that affect crop growth and development, as well as, design assays for the cytotoxicity and binding affinity of potential pesticides. The clone and other methods described herein, permit the manipulation of natural and/or introduced homologous receptors and, thus, to specifically destroy organisms, tissues and/or cells of the target host.Type: GrantFiled: July 18, 2003Date of Patent: August 22, 2006Assignee: The Board of Regents, The University of Texas SystemInventors: Lee A. Bulla, Mehmet Candas
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Publication number: 20050266524Abstract: Recombinant materials for the production of ? integrin protein characteristic of Manduca sexta are useful for screening pesticides for this moth.Type: ApplicationFiled: November 29, 2004Publication date: December 1, 2005Inventors: Lee Bulla, Mehmet Candas
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Publication number: 20050196807Abstract: The present invention provides a system, method and apparatus for targeting gene sequences having one or more phenotypic characteristics using a computer. One or more phenotypic characteristics are selected. A gene sequence is then selected that is known to have the selected phenotypic characteristics. In addition, one or more databases containing cataloged gene sequences are selected. The selected gene sequence is compared to the cataloged gene sequences, and any cataloged gene sequences that contain a portion of the selected gene sequence are extracted. The selected gene sequence is aligned to each portion of the extracted gene sequence and the extracted gene sequences are prioritized based on the alignment of the selected gene sequence. At least one of the prioritized gene sequences is selected based on one or more phenotypic criteria. Finally, one or more degenerate primers are designed to target the selected-prioritized gene sequences.Type: ApplicationFiled: April 26, 2005Publication date: September 8, 2005Inventors: Lee Bulla, Mehmet Candas
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Patent number: 6928368Abstract: The present invention provides a system, method and apparatus for targeting gene sequences having one or more phenotypic characteristics using a computer. One or more phenotypic characteristics are selected. A gene sequence is then selected that is known to have the selected phenotypic characteristics. In addition, one or more databases containing cataloged gene sequences are selected. The selected gene sequence is compared to the cataloged gene sequences, and any cataloged gene sequences that contain a portion of the selected gene sequence are extracted. The selected gene sequence is aligned to each portion of the extracted gene sequence and the extracted gene sequences are prioritized based on the alignment of the selected gene sequence. At least one of the prioritized gene sequences is selected based on one or more phenotypic criteria. Finally, one or more degenerate primers are designed to target the selected-prioritized gene sequences.Type: GrantFiled: October 25, 2000Date of Patent: August 9, 2005Assignee: The Board Regents, The University of Texas SystemInventors: Lee A. Bulla, Jr., Mehmet Candas
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Publication number: 20040248276Abstract: A bacterial protein which converts 2-methyl citrate to 2-methyl isocitrate is a previously unknown target for antibacterial agents. The protein of this activity is associated with mucoid bacteria and inhibitors of production or activity of this protein in combination with propionic acid mitigate the virulence of these bacteria.Type: ApplicationFiled: May 19, 2003Publication date: December 9, 2004Inventors: Mehmet Candas, Lee A. Bulla
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Publication number: 20040229207Abstract: A novel microorganism producing a nontoxic, non-antigenic exopolysaccharide is taught. The exopolysaccharide has neutral sugars migrating at the same rate as mannose, fucose, fructose and galactose, acidic sugars migrating at the same rate as fucose and amine sugars migrating at the same rate as glucose and fucose, and wherein the ratio of galactose:fucose:glucose:mannose is about 1:2:3:6. The microbe and the exopolysaccharide have uses as a biofilm in geologic applications and have several consumer uses as food and drug polymers and use as a plasma extender.Type: ApplicationFiled: June 14, 2004Publication date: November 18, 2004Inventors: Lee A. Bulla, Mehmet Candas
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Patent number: 6797490Abstract: A composition and method for killing fire ants is disclosed that includes the purified and activated Cry toxin from a novel strain of Bacillus thuringiensis, wherein the water soluble, partially purified, activated toxin is provided along with an attractant to kill the imported fire ant using a biodegradable, environmentally sound glycoprotein without a need for toxic chemicals.Type: GrantFiled: August 16, 2002Date of Patent: September 28, 2004Assignee: The Board of Regents, The University of Texas SystemInventors: Lee A. Bulla, Jr., Mehmet Candas
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Patent number: 6759230Abstract: A novel microorganism producing a nontoxic, non-antigenic exopolysaccharide is taught. The exopolysaccharide has neutral sugars migrating at the same rate as mannose, fucose, fructose and galactose, acidic sugars migrating at the same rate as fucose and amine sugars migrating at the same rate as glucose and fucose, and wherein the ratio of galactose:fucose:glucose:mannose is about 1:2:3:6. The microbe and the exopolysaccharide have uses as a biofilm in geologic applications and have several consumer uses as food and drug polymers and use as a plasma extender.Type: GrantFiled: October 25, 2000Date of Patent: July 6, 2004Assignee: The Board of Regents, The University of TexasInventors: Lee A. Bulla, Jr., Mehmet Candas
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Publication number: 20040040059Abstract: A cDNA encoding a 200 kD receptor, BT-R2, from the pink boll worm, Pectinophora gossypiella, that binds specifically to a Bacillus thuringiensis toxin has been cloned, sequenced and characterized. The minimum toxin binding fragment has been identified. The BT-R2 cDNA permits the analysis of receptors in pink boll worm and other insects that affect crop growth and development, as well as, design assays for the cytotoxicity and binding affinity of potential pesticides. The clone and other methods described herein, permit the manipulation of natural and/or introduced homologous receptors and, thus, to specifically destroy organisms, tissues and/or cells of the target host.Type: ApplicationFiled: July 18, 2003Publication date: February 26, 2004Inventors: Lee A. Bulla, Mehmet Candas
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Patent number: 6660497Abstract: A cDNA encoding a 200 kD receptor, BT-R2, from the pink boll worm, Pectinophora gossypiella, that binds specifically to a Bacillus thuringiensis toxin has been cloned, sequenced and characterized. The minimum toxin binding fragment has been identified. The BT-R2 cDNA permits the analysis of receptors in pink boll worm and other insects that affect crop growth and development, as well as, design assays for the cytotoxicity and binding affinity of potential pesticides. The clone and other methods described herein, permit the manipulation of natural and/or introduced homologous receptors and, thus, to specifically destroy organisms, tissues and/or cells of the target host.Type: GrantFiled: October 24, 2000Date of Patent: December 9, 2003Assignee: The Board of Regents, The University of Texas SystemInventors: Lee A. Bulla, Jr., Mehmet Candas
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Patent number: 6551800Abstract: A nucleic acid derived from Bacillus thuringiensis contains a nucleotide sequence that encodes a polypeptide demonstrated to be toxic to fire ants.Type: GrantFiled: October 24, 2000Date of Patent: April 22, 2003Assignee: The Board of Regents, The University Texas SystemInventors: Lee A. Bulla, Jr., Mehmet Candas
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Publication number: 20030054391Abstract: A composition and method for killing fire ants is disclosed that includes the purified and activated Cry toxin from a novel strain of Bacillus thuringiensis, wherein the water soluble, partially purified, activated toxin is provided along with an attractant to kill the imported fire ant using a biodegradable, environmentally sound glycoprotein without a need for toxic chemicals.Type: ApplicationFiled: August 16, 2002Publication date: March 20, 2003Inventors: Lee A. Bulla, Mehmet Candas