Abstract: A method for cutting or extracting video clips from a video, including the audio content relevant to points of particular interest, and combining the same for instruction or training on particular points; a computing device applying the method extracts text information from the spoken audio content of a video to be cut and obtains multiple paragraph segmentation positions as candidates for inclusion in a desired and finished presentation by analyzing the information from text representing the spoken audio content, the analysis being carried out by a semantic segmentation model. Candidate items of text are obtained by isolating pieces of text according to the paragraph segmentation positions. Time stamps of the candidate text segments are acquired, and candidate video clips are obtained by cutting the video according to the acquired time stamps.

Abstract: The present invention relates to novel pyridazin-3-yl phenol compounds of formula (I): wherein R1, R2, R3, R4 and R5 are defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical compositions and medicaments containing them, and their use in the treatment of diseases and disorders mediated by NLRP3.

Abstract: The present disclosure provides polymorphs and formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I). The present disclosure further provides methods for treating ocular surface pain by administering 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I). The present invention also provides 5 methods for treating dry eye disease and ocular hyperemia by administering 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile.