Patents by Inventor Melanie Briegel

Melanie Briegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing recloning efficiency
    Patent number: 8563303
    Abstract: The present invention relates to the field of cell culture technology and relates to methods of replicating/cloning cells, preferably cell lines which are important for the production of biopharmaceuticals. The invention also relates to methods of preparing proteins using cells that have been obtained and replicated by single cell deposition and compositions which make it possible to replicate individual cells. By using IGF particularly in conjunction with HSA in the culture medium after recloning, the recloning efficiency and hence the quantity of clones obtained can be increased significantly.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: October 22, 2013
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Jüergen Fieder, Lore Florin, Hitto Kaufmann, Thomas Krieg, Melanie Briegel
  • METHOD FOR INCREASING RECLONING EFFICIENCY
    Publication number: 20110230642
    Abstract: The present invention relates to the field of cell culture technology and relates to methods of replicating/cloning cells, preferably cell lines which are important for the production of biopharmaceuticals. The invention also relates to methods of preparing proteins using cells that have been obtained and replicated by single cell deposition and compositions which make it possible to replicate individual cells. By using IGF particularly in conjunction with HSA in the culture medium after recloning, the recloning efficiency and hence the quantity of clones obtained can be increased significantly.
    Type: Application
    Filed: March 16, 2009
    Publication date: September 22, 2011
    Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Juergen Fieder, Lore Florin, Hitto Kaufmann, Thomas Krieg, Melanie Briegel