Patents by Inventor Melanie P. MATHEU

Melanie P. MATHEU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11919231
    Abstract: In an aspect, the present disclosure provides a method for printing an object, comprising: directing at least one energy beam from an energy source into a media chamber comprising at least one polymeric precursor to generate said object at a fine resolution within a certain time period.
    Type: Grant
    Filed: June 22, 2021
    Date of Patent: March 5, 2024
    Assignee: Prellis Biologics, Inc.
    Inventors: Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
  • Patent number: 11767514
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: September 26, 2023
    Assignee: PRELLIS BIOLOGICS, INC
    Inventors: Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
  • Publication number: 20220212407
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Application
    Filed: March 24, 2022
    Publication date: July 7, 2022
    Inventor: Melanie P. MATHEU
  • Publication number: 20220195394
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Application
    Filed: March 14, 2022
    Publication date: June 23, 2022
    Inventors: Melanie P. MATHEU, Kathryn J. PARKINSON, Emma R. MOULTON
  • Publication number: 20220081674
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Application
    Filed: June 22, 2021
    Publication date: March 17, 2022
    Inventors: Melanie P. MATHEU, Kathryn J. PARKINSON, Emma R. MOULTON
  • Publication number: 20220025322
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional cell-containing matrixes. Further, provided herein are methods and systems for generating a three-dimensional (3D) structure corresponding to a biological material, such as a kidney or lung comprising either nephron or alveolar structures. Also provided herein are bio-printed three-dimensional matrices for use in the generation nephron and/or alveolar structures.
    Type: Application
    Filed: May 12, 2021
    Publication date: January 27, 2022
    Inventors: Melanie P. MATHEU, Karl Johan Torbjorn BORGLIN
  • Publication number: 20210394437
    Abstract: The present disclosure provides methods and systems for the three-dimensional (3D) printing of 3D objects. Methods and systems provided herein may comprise 3D holographic lithography which may enable the 3D printing of various shapes. Methods and systems provided herein may enable high efficiency 3D holographic printing and may avoid, for example, problems zero-order defects. Methods and systems provided herein comprise methods for printing 3D objects with reduced or minimal inconsistency.
    Type: Application
    Filed: January 29, 2021
    Publication date: December 23, 2021
    Inventors: Melanie P. MATHEU, Erik BUSBY, Karl Johan Torbjorn BORGLIN, Christopher ROGERS, Hershel SHAH
  • Publication number: 20210361584
    Abstract: The present disclosure provides methods and systems for optically-induced auto-encapsulation. A method of the present disclosure comprises providing a media chamber comprising a medium comprising (i) a three-dimensional (3D) object comprising a photo-emitter, (ii) at least one polymeric precursor, and (iii) a photoinitiator, and subjecting the medium in the media chamber to a stimulus (e.g., an energy beam or a chemical stimulus) to induce photo-emission from the photo-emitter to trigger the formation of a polymer matrix from the at least one polymeric precursor, which polymer matrix at least partially encapsulates the 3D object.
    Type: Application
    Filed: January 29, 2021
    Publication date: November 25, 2021
    Inventors: Melanie P. MATHEU, Erik BUSBY, Christopher ROGERS, Milad KHORRAMI
  • Publication number: 20210339465
    Abstract: The present disclosure provides methods and systems for printing a three-dimensional (3D) material. In some examples, a method for printing a 3D biological material comprises providing a media chamber comprising a medium comprising (i) a plurality of cells and (ii) one or more polymer precursors. Next, at least one energy beam may be directed to the medium in the media chamber along at least one energy beam path that is patterned into a 3D projection wherein the x, y, and z dimensions may be simultaneously accessed in accordance with computer instructions for printing the 3D biological material in computer memory, to form at least a portion of the 3D biological material comprising (i) at least a subset of the plurality of cells, and (ii) a polymer formed from the one or more polymer precursors.
    Type: Application
    Filed: November 25, 2020
    Publication date: November 4, 2021
    Inventor: Melanie P. MATHEU
  • Patent number: 11085018
    Abstract: Provided herein are methods and systems for forming a three-dimensional object corresponding to an organ or organoid. A method for forming a three-dimensional object corresponding to an organ or organoid may comprise generating a plurality of discrete focal points patterned as a 3D projection corresponding to the organ or organoid in a medium comprising one or more precursors of a polymer, to form at least a portion of the 3D object corresponding to the organ or organoid.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: August 10, 2021
    Assignee: PRELLIS BIOLOGICS, INC.
    Inventors: Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
  • Patent number: 10933579
    Abstract: The present disclosure provides methods and systems for printing a three-dimensional (3D) material. In some examples, a method for printing a 3D biological material comprises providing a media chamber comprising a medium comprising (i) a plurality of cells and (ii) one or more polymer precursors. Next, at least one energy beam may be directed to the medium in the media chamber along at least one energy beam path that is patterned into a 3D projection wherein the x, y, and z dimensions may be simultaneously accessed in accordance with computer instructions for printing the 3D biological material in computer memory, to form at least a portion of the 3D biological material comprising (i) at least a subset of the plurality of cells, and (ii) a polymer formed from the one or more polymer precursors.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: March 2, 2021
    Assignee: PRELLIS BIOLOGICS, INC.
    Inventor: Melanie P. Matheu
  • Publication number: 20200080060
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Application
    Filed: October 30, 2019
    Publication date: March 12, 2020
    Inventors: Melanie P. MATHEU, Kathryn J. PARKINSON, Emma R. MOULTON
  • Publication number: 20200063093
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Inventors: Melanie P. MATHEU, Kathryn J. PARKINSON, Emma R. MOULTON
  • Patent number: 10513691
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: December 24, 2019
    Assignee: PRELLIS BIOLOGICS, INC.
    Inventors: Melanie P. Matheu, Kathryn J. Parkinson, Emma R. Moulton
  • Publication number: 20190010463
    Abstract: Provided herein are methods and systems for bio-printing of three-dimensional organs and organoids. Also provided herein are bio-printed three-dimensional organs and organoids for use in the generation and/or the assessment of immunological products and/or immune responses. Also provided herein are methods and system for bio-printing three-dimensional matrices.
    Type: Application
    Filed: July 24, 2018
    Publication date: January 10, 2019
    Inventors: Melanie P. MATHEU, Kathryn J. PARKINSON, Emma R. MOULTON
  • Publication number: 20180257297
    Abstract: The present disclosure provides methods and systems for printing a three-dimensional (3D) material. In some examples, a method for printing a 3D biological material comprises providing a media chamber comprising a medium comprising (i) a plurality of cells and (ii) one or more polymer precursors. Next, at least one energy beam may be directed to the medium in the media chamber along at least one energy beam path that is patterned into a 3D projection wherein the x, y, and z dimensions may be simultaneously accessed in accordance with computer instructions for printing the 3D biological material in computer memory, to form at least a portion of the 3D biological material comprising (i) at least a subset of the plurality of cells, and (ii) a polymer formed from the one or more polymer precursors.
    Type: Application
    Filed: March 19, 2018
    Publication date: September 13, 2018
    Inventor: Melanie P. MATHEU