Patents by Inventor Melina Malinen

Melina Malinen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210190765
    Abstract: The present invention relates a method for chemical testing, comprising culturing cells in a first plant-derived nanofibrillar cellulose (NFC)hydrogel to obtain in vivo like cells; exposing the in vivo like cells to a test chemical; optionally within another plant-derived NFC hydrogel; incubating the exposed in vivo like cells; detecting during or after incubating, the impact of the test chemical on the in vivo like cells by at least one detection; and removing the plant-derived NFC hydrogel at least once at any stage after obtaining the in vivo like cells and before at least one detection used for detecting the impact of the test chemical on the in vivo like cells. The invention further relates to the use of plant-derived NFC hydrogel in a method for chemical testing, the use of in vivo like cells obtained by culturing cells in plant-derived NFC hydrogel for chemical testing and to a kit for chemical testing comprising plant-derived NFC hydrogel, instructions and a cell or test chemical library.
    Type: Application
    Filed: March 2, 2021
    Publication date: June 24, 2021
    Inventors: Marjo Yliperttula, Arto Urtti, Yan-Ru Lou, Melina Malinen, Patrick Laurén, Liisa Kanninen, Kirsti Johanna Niklander, Petter Somersalo, Riina Harjumäki
  • Patent number: 10976308
    Abstract: The present invention relates a method for chemical testing, comprising culturing cells in a first plant-derived nanofibrillar cellulose (NFC) hydrogel to obtain in vivo like cells; exposing the in vivo like cells to a test chemical; optionally within another plant-derived NFC hydrogel; incubating the exposed in vivo like cells; detecting during or after incubating, the impact of the test chemical on the in vivo like cells by at least one detection; and removing the plant-derived NFC hydrogel at least once at any stage after obtaining the in vivo like cells and before at least one detection used for detecting the impact of the test chemical on the in vivo like cells. The invention further relates to the use of plant-derived NFC hydrogel in a method for chemical testing, the use of in vivo like cells obtained by culturing cells in plant-derived NFC hydrogel for chemical testing and to a kit for chemical testing comprising plant-derived NFC hydrogel, instructions and a cell or test chemical library.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: April 13, 2021
    Assignee: UPM-KYMMENE CORPORATION
    Inventors: Marjo Yliperttula, Arto Urtti, Yan-Ru Lou, Melina Malinen, Patrick Laurén, Liisa Kanninen, Kirsti Johanna Niklander, Petter Somersalo, Riina Harjumäki
  • Publication number: 20180024121
    Abstract: The present invention relates a method for chemical testing, comprising culturing cells in a first plant-derived nanofibrillar cellulose (NFC) hydrogel to obtain in vivo like cells; exposing the in vivo like cells to a test chemical; optionally within another plant-derived NFC hydrogel; incubating the exposed in vivo like cells; detecting during or after incubating, the impact of the test chemical on the in vivo like cells by at least one detection; and removing the plant-derived NFC hydrogel at least once at any stage after obtaining the in vivo like cells and before at least one detection used for detecting the impact of the test chemical on the in vivo like cells. The invention further relates to the use of plant-derived NFC hydrogel in a method for chemical testing, the use of in vivo like cells obtained by culturing cells in plant-derived NFC hydrogel for chemical testing and to a kit for chemical testing comprising plant-derived NFC hydrogel, instructions and a cell or test chemical library.
    Type: Application
    Filed: December 18, 2015
    Publication date: January 25, 2018
    Inventors: Marjo Yliperttula, Arto Urtti, Yan-Ru Lou, Melina Malinen, Patrick Laurén, Liisa Kanninen, Johanna Niklander, Petter Somersalo, Riina Harjumäki