Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: A flexible disposable seat guard is created with an absorbent porous top layer and a watertight bottom layer uniquely designed to conform to the lower back and seat portion of various infant/child seats. The seat guard has flexible sides and corners allowing the stretchable material to conform to the angle of a safety harness and/or safety belt. The seat guard has compressed perforations on the lower back portion to adhere and conform to various infant seats. Compressed perforations are located on the bottom seat portion to allow for complete access to the harness latch.