Abstract: Techniques for instrument insertion control include a manipulator system. The manipulator system includes a manipulator configured to support an instrument and a control system coupled to the manipulator. The control system is configured to determine an insertion profile associated with at least one of the instrument or a cannula through which the instrument is configured to be inserted and resist or assist a manual insertion of the instrument through the cannula according to the insertion profile, wherein the resisting or assisting causes a velocity of the manual insertion to be uniform in response to a uniform force applied by the manual insertion.