Patents by Inventor Melvin KLEGERMAN

Melvin KLEGERMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING LIPOSOME-ENCAPSULATED THIAZOLIDINEDIONES AND LIPOSOME-ENCAPSULATED VASODILATORS, AND THEIR USE TO AMELIORATE ATHEROMA
    Publication number: 20240024237
    Abstract: Disclosed are compositions comprising a first liposome, comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, and at least one vasodilator; and a second liposome, comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, at least one thiazolidinedione, and at least one compound having an affinity for at least one component of an atheroma. Also disclosed are methods for forming the compositions and methods of using the compositions to ameliorate atheroma.
    Type: Application
    Filed: July 12, 2023
    Publication date: January 25, 2024
    Inventors: David D. McPherson, Shao-Ling Huang, Melvin Klegerman, Susan T. Laing, Patrick Kee, Tao Peng, Hyunggun Kim, Melanie Moody
  • Liquids rich in noble gas and methods of their preparation and use
    Patent number: 11491184
    Abstract: Provided herein is a novel composition for oral administration and delivery of Noble gas, such as xenon or argon. Methods of treating and preventing neuronal or cardiovascular damage with such compositions are also provided.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: November 8, 2022
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Shao-Ling Huang, David McPherson, Yong-Jian Geng, Xing Yin, Hyunggun Kim, Melvin Klegerman, Tao Peng
  • LIQUIDS RICH IN NOBLE GAS AND METHODS OF THEIR PREPARATION AND USE
    Publication number: 20200215100
    Abstract: Provided herein is a novel composition for oral administration and delivery of Noble gas, such as xenon or argon. Methods of treating and preventing neuronal or cardiovascular damage with such compositions are also provided.
    Type: Application
    Filed: December 3, 2019
    Publication date: July 9, 2020
    Inventors: Shao-Ling HUANG, David MCPHERSON, Yong-Jian GENG, Xing YIN, Hyunggun KIM, Melvin KLEGERMAN, Tao PENG
  • COMPOSITIONS COMPRISING LIPOSOME-ENCAPSULATED THIAZOLIDINEDIONES AND LIPOSOME-ENCAPSULATED VASODILATORS, AND THEIR USE TO AMELIORATE ATHEROMA
    Publication number: 20190365649
    Abstract: Disclosed are compositions comprising a first liposome, comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, and at least one vasodilator; and a second liposome, comprising at least one lipid selected from the group consisting of saturated phospholipids, unsaturated phospholipids, mixed phospholipids, and cholesterol, at least one thiazolidinedione, and at least one compound having an affinity for at least one component of an atheroma. Also disclosed are methods for forming the compositions and methods of using the compositions to ameliorate atheroma.
    Type: Application
    Filed: May 31, 2019
    Publication date: December 5, 2019
    Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: David D. McPherson, Shao-Ling Huang, Melvin Klegerman, Susan T. Laing, Patrick Kee, Tao Peng, Hyunggun Kim, Melanie Moody
  • LIQUIDS RICH IN NOBLE GAS AND METHODS OF THEIR PREPARATION AND USE
    Publication number: 20180271897
    Abstract: Provided herein is a novel composition for oral administration and delivery of Noble gas, such as xenon or argon. Methods of treating and preventing neuronal or cardiovascular damage with such compositions are also provided.
    Type: Application
    Filed: September 5, 2017
    Publication date: September 27, 2018
    Inventors: Shao-Ling HUANG, David MCPHERSON, Yong-Jian GENG, Xing YIN, Hyunggun KIM, Melvin KLEGERMAN, Tao PENG
  • LIQUIDS RICH IN NOBLE GAS AND METHODS OF THEIR PREPARATION AND USE
    Publication number: 20160030470
    Abstract: Provided herein is a novel composition for oral administration and delivery of Noble gas, such as xenon or argon. Methods of treating and preventing neuronal or cardiovascular damage with such compositions are also provided. The present invention relates generally to the fields of molecular biology, medicine and nutraceuticals. More particularly, it concerns methods for oral delivery of inert gas compositions, such as Xenon or Argon, for the treatment and prevention of disease.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 4, 2016
    Inventors: Shao-Ling HUANG, David MCPHERSON, Yong-Jian GENG, Xing YIN, Hyunggun KIM, Melvin KLEGERMAN, Tao PENG