Patents by Inventor Mengxiao Shi

Mengxiao Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of functionalized indolizidines
    Patent number: 7285667
    Abstract: The present invention provides a process for the preparation of functionalized indolizidines comprising the steps and products disclosed within this application.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: October 23, 2007
    Assignee: Wyeth
    Inventors: Ariamala Gopalsamy, Mengxiao Shi
  • Pyrazolo[1,5-A]pyrimidine derivatives and methods of use thereof
    Publication number: 20070219186
    Abstract: The present invention relates to pyrazolo[1,5-a]pyrimidine derivatives, compositions comprising an effective amount of a pyrazolo[1,5-a]pyrimidine derivative and methods for treating or preventing cancer, comprising administering to a subject in need thereof an effective amount of a pyrazolo[1,5-a]pyrimidine derivative.
    Type: Application
    Filed: March 15, 2007
    Publication date: September 20, 2007
    Inventors: Ariamala Gopalsamy, Gregory Ciszewski, Mengxiao Shi, Dan Berger, Nancy Torres, Jeremy Levin, Dennis Powell
  • Carbazole and cyclopentaindole derivatives to treat infection with Hepatitis C virus
    Patent number: 7250441
    Abstract: The invention is directed to a method of treating, preventing, or inhibiting a Hepatitis C viral infection in a mammal comprising contacting the mammal with an effective amount of a compound of the formula: wherein substitutions at R1-R13, m and Y are set forth in the specification.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: July 31, 2007
    Assignee: Wyeth
    Inventors: Ariamala Gopalsamy, Gregory Mark Ciszewski, Mengxiao Shi, Kaapjoo Park
  • Dibenzonaphthyridine derivatives and methods of use thereof
    Publication number: 20070135429
    Abstract: The present invention relates to Dibenzonaphthyridine Derivatives, compositions comprising an effective amount of a Dibenzonaphthyridine Derivative and methods for treating or preventing a proliferative disorder, comprising administering to a subject in need thereof an effective amount of a Dibenzonaphthyridine Derivative.
    Type: Application
    Filed: December 6, 2006
    Publication date: June 14, 2007
    Applicant: Wyeth
    Inventors: Ariamala Gopalsamy, Mengxiao Shi, Kristina Kutterer, Kim Arndt
  • Diarylsulfone sulfonamides and use thereof
    Publication number: 20060276464
    Abstract: Compounds of Formula 1, or pharmaceutically acceptable salts thereof, are provided: which are modulators of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis.
    Type: Application
    Filed: May 10, 2006
    Publication date: December 7, 2006
    Applicant: Wyeth
    Inventors: Ariamala Gopalsamy, William Moore, Jeffery Kern, Albert Molinari, Mengxiao Shi, Gregory Welmaker, Mathew Wilson, Girija Krishnamurthy, Thomas Commons, Michael Webb, Richard Woodworth
  • Iminothiazolidinone derivatives as SFRP-1 antagonists
    Publication number: 20060270720
    Abstract: Compounds of Formula 1, or pharmaceutically acceptable salts thereof, are provided: which are inhibitors of secreted frizzled related protein-1. The compounds, and compositions containing the compounds, can be used to treat a variety of disorders, including osteoporosis.
    Type: Application
    Filed: May 10, 2006
    Publication date: November 30, 2006
    Applicant: Wyeth
    Inventors: Ariamala Gopalsamy, Mengxiao Shi
  • Process for the synthesis of functionalized indolizidines
    Publication number: 20060241306
    Abstract: The present invention provides a process for the preparation of functionalized indolizidines comprising the steps and products disclosed within this application.
    Type: Application
    Filed: April 20, 2006
    Publication date: October 26, 2006
    Applicant: Wyeth
    Inventors: Ariamala Gopalsamy, Mengxiao Shi
  • Carbazole and cyclopentaindole derivatives to treat infection with Hepatitis C virus
    Publication number: 20060063821
    Abstract: The invention is directed to a method of treating, preventing, or inhibiting a Hepatitis C viral infection in a mammal comprising contacting the mammal with an effective amount of a compound of the formula: wherein substitutions at R1-R13, m and Y are set forth in the specification.
    Type: Application
    Filed: September 21, 2005
    Publication date: March 23, 2006
    Applicant: Wyeth
    Inventors: Ariamala Gopalsamy, Gregory Ciszewski, Mengxiao Shi, Kaapjoo Park