Patents by Inventor Ömer Reis

Ömer Reis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the synthesis of rasagiline
    Patent number: 8901352
    Abstract: We have developed a new method for the synthesis of Rasagiline (Formula 1) based on the alkylation of trifluoroacetyl protected aminoindan. This protection enabled us to carry out an alkylation of aminoindan with a high yield and purity under very mild conditions with a wide range of reaction conditions and reagent selection. Considering the ease, purity and high yields of introducing and removal of the trifluoroacetyl group, this approach is a highly practical and economical way for the synthesis of rasagiline or its pharmaceutically acceptable salts.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: December 2, 2014
    Assignee: Nobel Ilaç Sanayii Ve Ticaret A.S.
    Inventors: Ömer Reis, Hasan Koyuncu, Ilker Esiringu, Yasemin Sahin, H. Ozan Gulcan
  • NEW METHOD FOR THE SYNTHESIS OF RASAGILINE
    Publication number: 20140018578
    Abstract: We have developed a new method for the synthesis of Rasagiline (Formula 1) based on the alkylation of trifluoroacetyl protected aminoindan. This protection enabled us to carry out an alkylation of aminoindan with a high yield and purity under very mild conditions with a wide range of reaction conditions and reagent selection. Considering the ease, purity and high yields of introducing and removal of the trifluoroacetyl group, this approach is a highly practical and economical way for the synthesis of rasagiline or its pharmaceutically acceptable salts.
    Type: Application
    Filed: January 13, 2011
    Publication date: January 16, 2014
    Inventors: Ömer Reis, Hasan Koyuncu, Ilker Esiringu, Yasemin Sahin, H. Ozan Gulcan