Patents by Inventor Merrill Garnett

Merrill Garnett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10472379
    Abstract: The described invention provides a compound comprising an organometallic complex comprising a core of ruthenium and sphingomyelin, with the option of added zinc, that, in a therapeutic amount, through further connections with contributing organic ligands, are effective as chemotherapeutic agents that have an anti-tumor or anti-cancer effect on a tumor comprising tumor cells including a cytotoxic effect on of the tumor cells, inhibition of the growth of the tumor comprising the tumor cells, inhibition of migration of the tumor cells, or any combination of these effects.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: November 12, 2019
    Inventor: Merrill Garnett
  • Publication number: 20180169062
    Abstract: The present invention provides a method for enhancing the anti-tumor effects of radiation therapy in a subject in need thereof. The method includes administering an effective amount of a composition comprising a palladium lipoic acid complex prior to, or along with, radiation therapy.
    Type: Application
    Filed: May 26, 2016
    Publication date: June 21, 2018
    Inventor: Merrill Garnett
  • Publication number: 20180051045
    Abstract: The described invention provides a compound comprising an organometallic complex comprising a core of ruthenium and sphingomyelin, with the option of added zinc, that, in a therapeutic amount, through further connections with contributing organic ligands, are effective as chemotherapeutic agents that have an anti-tumor or anti-cancer effect on a tumor comprising tumor cells including a cytotoxic effect on of the tumor cells, inhibition of the growth of the tumor comprising the tumor cells, inhibition of migration of the tumor cells, or any combination of these effects.
    Type: Application
    Filed: May 8, 2017
    Publication date: February 22, 2018
    Inventor: Merrill Garnett
  • Patent number: 9605012
    Abstract: The described invention provides organometallic complexes capable of spin transfer, comprising at least three different metals and the use of pharmaceutical compositions comprising such complexes in detoxification of reactive oxygen species in inflammatory conditions.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: March 28, 2017
    Assignee: Garnett McKeen Laboratory, Inc.
    Inventor: Merrill Garnett
  • Publication number: 20140199407
    Abstract: The described invention provides organometallic complexes capable of spin transfer, comprising at least three different metals and the use of pharmaceutical compositions comprising such complexes in detoxification of reactive oxygen species in inflammatory conditions.
    Type: Application
    Filed: March 11, 2013
    Publication date: July 17, 2014
    Inventor: Merrill Garnett
  • Publication number: 20130123227
    Abstract: The present invention relates generally to novel complexes of palladium or a palladium salt, lipoic acid and a long chain fatty acid, where the palladium is bonded to lipoic acid via both sulfurs and carboxyl group oxygens of lipoic acid, and where the long chain fatty acid is bonded to the palladium via the carboxyl group of the long chain fatty acid. The complexes are useful as cancer chemotherapy agents.
    Type: Application
    Filed: April 12, 2011
    Publication date: May 16, 2013
    Inventor: Merrill Garnett
  • Patent number: 5776973
    Abstract: Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium).sub.m (lipoic acid).sub.n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is also disclosed. In addition, a method of treatment of tumors and a method of treatment of psoriasis comprising administering the pharmaceutical compositions of the present invention are provided.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: July 7, 1998
    Inventor: Merrill Garnett
  • Patent number: 5679697
    Abstract: Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium).sub.m (lipoic acid).sub.n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is also disclosed. In addition, a method of treatment of tumors and a method of treatment of psoriasis comprising administering the pharmaceutical compositions of the present invention are provided.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: October 21, 1997
    Inventor: Merrill Garnett
  • Patent number: 5463093
    Abstract: Novel palladium complexes and pharmaceutical compositions comprising the same are provided. Such complexes comprise (palladium).sub.m (lipoic acid).sub.n, wherein m and n are each independently 1 or 2. A process for preparing such complexes is also disclosed. In addition, a method of treatment of tumors and a method of treatment of psoriasis comprising administering the pharmaceutical compositions of the present invention are provided.
    Type: Grant
    Filed: November 26, 1993
    Date of Patent: October 31, 1995
    Inventor: Merrill Garnett
  • Patent number: 4051804
    Abstract: Thaw-indicator for frozen articles including a V-shaped transparent elastomeric tube having its inner wall surfaces disposed in liquid tight interfacial engagement at the apex of the V by a removable band and defining a pair of closed liquid containers, adapted to contain freezable contrasting liquid dyes.
    Type: Grant
    Filed: March 1, 1976
    Date of Patent: October 4, 1977
    Assignee: Garnett-McKeen Chemical Corporation
    Inventor: Merrill Garnett