Abstract: The present invention provides a scalable digital twin system structure and a scalable digital twin service method that are capable of, based on a digital twin, performing real-time control of the real world while providing information required for the user to determine the optimal countermeasure in solve real-world problems in stages, thereby helping rapidly solve problems of the real-world. In order to preemptively respond to the real-world problems by providing decision support information with improved reliability according to a timeline based on a digital twin of a scalable structure, the operation of the digital twin is divided into several stages according to complexity and a result of each stage is transferred to an application service and the next stage, so that as the stage becomes higher, a more reliable result can be provided.

Abstract: The present invention relates to an antigen composition for preventing or treating viral infectious diseases, comprising, as an active ingredient, a multiple variant protein of a recombinant hemagglutinin monomeric protein in an influenza virus. In addition, the present invention relates to an antigen composition for preventing or treating viral infectious diseases, comprising a scaffold-based fusion protein. The antigen composition for preventing or treating viral infectious diseases, according to the present invention, has an outstanding preventive effect of inhibiting the proliferation and replication of viruses having various mutations, and is recyclable and safe by means of using a recombinant protein, and thus can be widely used in various industrial fields, such as the medicine and life science fields.