Patents by Inventor Mia Engstrom

Mia Engstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Somatostatin receptor 1 and/or 4 selective agonists and antagonists
    Patent number: 7741362
    Abstract: The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: June 22, 2010
    Assignee: Siegfried Wurster
    Inventors: Jussi Tomperi, Paivi Hautamaki, Harri Salo, Mia Engstrom, Andrei Tauber, Anna-Marja Hoffren, Siegfried Wurster
  • Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4
    Publication number: 20100048549
    Abstract: The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein A, D, E, J, Q1 R1, R2, R3, p and j are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes sst1 and/or sst4 and can be used for the treatment or diagnosis of diseases or conditions wherein sst1 and/or sst4 agonists or antagonists are indicated to be useful.
    Type: Application
    Filed: May 16, 2006
    Publication date: February 25, 2010
    Inventors: Jussi Tomperi, Harri Salo, Oili Kallatsa, Pia Knuuttila, Päivi Laakso, Iisa Höglund, Anna-Marja Hoffrén, Kurt Kokko, Pauli Saarenketo, Mia Engström, Siegfried Wurster
  • Somatostatin Receptor 1 and/or 4 Selective Agonists and Antagonists
    Publication number: 20100004339
    Abstract: The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful.
    Type: Application
    Filed: September 14, 2009
    Publication date: January 7, 2010
    Applicant: OY JUVANTIA PHARMA LTD.
    Inventors: Jussi Tomperi, Päivi Hautamäki, Harri Salo, Mia Engström, Andrei Tauber, Anna-Marja Hoffrén, Siegfried Wurster
  • Sulfonylamino-peptidomimetics active on the somatostatin receptor subtypes 4 (sstr4) and 1 (sstr1)
    Publication number: 20070129313
    Abstract: The invention relates to 1-naphthalenesulfonylamino based peptidomimetics of formula (I), wherein B, R1 and R2 are as defined in the claims, and pharmaceutically acceptable salts thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtype SSTR4 or the somatostatin receptor subfamily SSTR1/SSTR4.
    Type: Application
    Filed: October 5, 2004
    Publication date: June 7, 2007
    Applicant: SIEGFRIED WURSTER
    Inventors: Jussi Tomperi, Mia Engstrom, Siegfried Wurster
  • Somatostatin receptor 1 and/or 4 selective agonists and antagonists
    Publication number: 20070129422
    Abstract: The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful.
    Type: Application
    Filed: October 5, 2004
    Publication date: June 7, 2007
    Applicant: OY Juvantia Pharma LTD
    Inventors: Jussi Tomperi, Paivi Hautamaki, Harri Salo, Mia Engstrom, Andrei Tauber, Anna-Marja Hoffren, Siegfried Wurster
  • Derivatives of quinoline as alpha-2 antagonists
    Publication number: 20030225078
    Abstract: A compound of formula I, 1
    Type: Application
    Filed: April 16, 2003
    Publication date: December 4, 2003
    Applicants: Orion Corporation, Oy Juvantia Pharma Ltd.
    Inventors: Siegfried Wurster, Mia Engstrom, Juha-Matti Savola, Iisa Hoglund, Jukka Sallinen, Antti Haapalinna, Andrei Yurievitch Tauber, Anna-Marja Katariina Hoffren, Harri Elias Salo
  • Dervatives of quinoline as alpha-2 antagonists
    Patent number: 6593324
    Abstract: A compound of formula I, wherein A, Ra, Rb, R1 to R5, m and t are as defined as disclosed, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds I can be used for the treatment of diseases or conditions where alpha-2 antagonists are indicated to be effective.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: July 15, 2003
    Assignees: Orion Corporation, Oy Juvantia Pharma Ltd.
    Inventors: Siegfried Wurster, Mia Engström, Juha-Matti Savola, Iisa Höglund, Jukka Sallinen, Antti Haapalinna, Andrei Yurievitch Tauber, Anna-Marja Katariina Hoffrén, Harri Elias Salo
  • Method for the treatment or prevention of a disease mediated by the alpha-2B-adrenoceptor
    Patent number: 6521632
    Abstract: A method for the treatment or prevention of a disease mediated by the alpha-2B-adrenoceptor in a mammal. The method includes administering to the mammal an effective amount of a selective (alpha-2B-adrenoceptor antagonist, where the antagonist is a compound selected from the group consisting of compounds A, B, C, D and E disclosed in Scheme I, or a pharmaceutically acceptable salt of the compound.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: February 18, 2003
    Assignee: Oy Juvantia Pharma LTD
    Inventors: Siegfried Wurster, Mia Engström, Liisa Huovinen, Sari Kalliokoski, Leila Kelanne, Eeva-Liisa Savola
  • Method for the treatmennt or prevention of a disease mediated by the alpha-2B-adrenoceptor
    Publication number: 20020058618
    Abstract: The present invention relates to a method for the treatment or prevention of a disease mediated by the alpha-2B-adrenoceptor in a mammal. Said method comprises administering to said mammal an effective amount of a selective alpha-2B-adrenoceptor antagonist, wherein said antagonist is a compound selected from the group consisting of compounds A, B, C, D and E disclosed in Scheme I, or a pharmaceutically acceptable salt of said compound.
    Type: Application
    Filed: February 2, 2001
    Publication date: May 16, 2002
    Inventors: Siegfried Wurster, Mia Engstrom, Liisa Huovinen, Sari Kalliokoski, Leila Kelanne, Eeva-Liisa Savola
  • Derivatives of quinoline as alpha-2 antagonists
    Publication number: 20010046991
    Abstract: A compound of formula I, 1
    Type: Application
    Filed: February 28, 2001
    Publication date: November 29, 2001
    Inventors: Siegfried Wurster, Mia Engstrom, Juha-Matti Savola, Iisa Hoglund, Jukka Sallinen, Antti Haapalinna, Andrei Yurievitch Tauber, Anna-Marja Katariina Hoffren, Harri Elias Salo