Abstract: A micro-reaction device for preparing biodiesel by base catalysis includes a feeding system, a micro-reaction apparatus, and a separation apparatus. The feeding system is in communication with the micro-reaction apparatus, and the micro-reaction apparatus is in communication with the separation apparatus; the micro-reaction apparatus includes a micro-reactor, and the micro-reactor is a micro-dispersion micro-reactor; in the micro-reaction apparatus, an oil phase and short chain alcohols undergo an ester exchange reaction under base catalysis to generate fatty acid esters and by-product glycerol; and the micro-dispersion reactor is provided with a micro-dispersion structure for dispersing the short chain alcohols into micro-droplets.

Abstract: A correction method for a microseism interpretation fracturing fracture parameter result. The method includes classifying the communication modes of a block sampling fractured wells to be corrected according to the matching degree of micro seismic monitoring result and sand adding amount; correcting the volume coefficient of each said classified fractured well single well, and the volume correction coefficient By of each said fractured well is: B v = [ L 5 / 4 ? H ] T [ L 5 / 4 ? H ] W , wherein, [L5/4H]W is a calculation value of a micro seismic monitoring interpretation result; [L5/4H]T is a theoretical calculation value obtained by using field construction parameters; C, calculating the classification volume correction coefficient of each class of fractured wells according to the calculated single well volume correction coefficient of each said fractured well.

Abstract: A modeling method is provided. The modeling method includes: extracting multiple pieces of logging data corresponding to a plurality of logging characteristic parameters at different drilling depths of a sample well, based on a logging information of the sample well; marking the different drilling depths based on a lost circulation information of the sample well to distinguish lost circulation points and non-lost circulation points; and classifying the lost circulation points and the non-lost circulation points by adopting a random forest algorithm, based on the plurality of logging characteristic parameters and the multiple pieces of marked logging data at the different drilling depths, to establish a plurality of corresponding relations between the logging characteristic parameters and a lost circulation or non-lost circulation result, so as to obtain a diagnosis model.

Abstract: A modeling method is provided. The modeling method includes: extracting multiple pieces of logging data corresponding to a plurality of logging characteristic parameters at different drilling depths of a sample well, based on a logging information of the sample well; marking the different drilling depths based on a lost circulation information of the sample well to distinguish lost circulation points and non-lost circulation points; and classifying the lost circulation points and the non-lost circulation points by adopting a random forest algorithm, based on the plurality of logging characteristic parameters and the multiple pieces of marked logging data at the different drilling depths, to establish a plurality of corresponding relations between the logging characteristic parameters and a lost circulation or non-lost circulation result, so as to obtain a diagnosis model.

Abstract: Apparatus and method for a physical simulation experiment of fracturing an unconventional oil and gas reservoir layer by layer by spiral perforation via a horizontal well bore. The apparatus includes an outer wellbore provided with at least three layers of spiral perforations, and an inner wellbore provided with at least three layers of through-holes. The method includes injecting fracturing fluid into the inner wellbore, and opening a first layer cracks of a stratum by the fracturing fluid passing the first through-hole layer and the first spiral perforation layer, opening a second layer cracks of the stratum by the fracturing fluid passing second through-hole layer and second spiral perforation layer and opening a third layer cracks of the stratum by the fracturing fluid passing third through-hole layer and third spiral perforation layer.

Abstract: Apparatus and method for a physical simulation experiment of fracturing an unconventional oil and gas reservoir layer by layer by spiral perforation via a horizontal well bore. The apparatus includes an outer wellbore provided with at least three layers of spiral perforations, and an inner wellbore provided with at least three layers of through-holes. The method includes injecting fracturing fluid into the inner wellbore, and opening a first layer cracks of a stratum by the fracturing fluid passing the first through-hole layer and the first spiral perforation layer, opening a second layer cracks of the stratum by the fracturing fluid passing second through-hole layer and second spiral perforation layer and opening a third layer cracks of the stratum by the fracturing fluid passing third through-hole layer and third spiral perforation layer.

Abstract: A multifunction health-care product and methods for preparing and using the same are provided. The health-care product contains a powder of lotus root joints and/or an extract of the joints as the main active ingredient. A preferred composition of the product contains 4-7.5 parts by weight extract of the joints, 2-15 parts by weight powder of lotus root joints, 0.08 to 2 parts by weight green tea and/or an extract thereof, and 0.08 to 0.5 parts by weight notoginseng and/or an extract thereof. The method for the preparation of the composition involves directly pulverizing the lotus root joints, putting the pulverized lotus root joints in product-grade solvent for extraction, and then filtering it to obtain a filtrate solution which is the extract of the joints. The health-care product can effectively improve IR, thus improving and preventing type-II diabetes mellitus, hypertension, hyperlipoidemia, and cardio-cerebral vascular diseases caused by being obese, and also has the effect of effecting weight loss.

Abstract: This invention relates to peptide ligand discovery and is particularly directed to a method for the discovery of agonists for membrane bound receptors. The inventive detection system involves the use of a "tethered" ligand for probing receptor binding. The general detection system includes a membrane, a membrane bound receptor, and a chimeric ligand presenting molecule. This chimeric protein forms the tethered ligand and in turn includes a membrane domain, a linker domain, a ligand domain, and a cleavable terminal domain. The "ligands" of the system are exposed by the addition of a specific peptidase that cleaves at the designated sequence. The sequence of the ligand that produces signal as a result of the interaction between the agonist and receptor can be then be isolated using sib selection.