Patents by Inventor Miaomiao Guo

Miaomiao Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11981669
    Abstract: A compound represented by formula (I) or a tautomer, an optical isomer, a nitrogen oxide, a solvate, a pharmaceutically acceptable salt or prodrug thereof are useful for treating or relieving an HIF-related and/or EPO-related disease or condition in patient. The preparation method for the compound, and use of a drug composition containing the compound and the compound or the drug composition in preparation of a drug are also provided.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: May 14, 2024
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD
    Inventors: Yan Zhang, Miaomiao Wei, Xuejiao Zhang, Guorui Mi, Hui An, Bing Wei, Qian Guo
  • Publication number: 20240147163
    Abstract: Disclosed are a sound generator and an audio device. The sound generator includes a magnetically conductive plate, a first magnetic structure, a second magnetic structure, a treble diaphragm, a treble voice coil, a bass diaphragm and a bass voice coil. The first magnetic structure includes a first washer including a first sub-washer located and a second sub-washer provided surrounding the first sub-washer, and a treble magnetic gap is formed between the first sub-washer and the second sub-washer. A bass magnetic gap is formed between the first magnetic structure and the second magnetic structure. The treble voice coil is provided on a side of the treble diaphragm close to the magnetically conductive plate and is provided corresponding to the treble magnetic gap. The bass voice coil is provided on a side of the bass diaphragm close to the magnetically conductive plate and is provided corresponding to the bass magnetic gap.
    Type: Application
    Filed: December 29, 2023
    Publication date: May 2, 2024
    Inventors: Miaomiao WANG, Xiaodong Guo, Chengfei Zhang, Chunfa Liu
  • Patent number: 11952400
    Abstract: Provided are a bovine rotavirus fusion protein and calf diarrhea multivalent vaccine. The bovine rotavirus fusion protein contains a VP6 fragment, wherein the VP6 fragment contains an amino acid sequence as represented by SEQ ID NO. 4, and at least one loop region of the following (a)˜(c) is substituted with an antigenic epitope derived from bovine coronavirus and/or an antigenic epitope derived from E. coli: (a) amino acid residues of sites 168-177; with an amino acid sequence as represented by SEQ ID NO. 1; (b) amino acid residues of sites 194-205; with an amino acid sequence as represented by SEQ ID NO. 2; and (a) amino acid residues of sites 296-316, with an amino acid sequence as represented by SEQ ID NO. 3, The bovine rotavirus fusion protein contains a plurality of antigenic epitopes, and can enable a host to generate a plurality of antibodies after immunizing the host.
    Type: Grant
    Filed: April 16, 2021
    Date of Patent: April 9, 2024
    Assignee: TECON BIOPHARMACEUTICAL CO., LTD.
    Inventors: Sun He, Yiping Pan, Guoqing Zhang, Pengxian Yan, Na Xi, Miaomiao Guo, Shengdong Xiao, Tianzeng Li, Rui Han, Yumeng Wang, Jiubin Du, Pei Zheng, Jian Cao
  • Publication number: 20220002350
    Abstract: Provided are a bovine rotavirus fusion protein and calf diarrhea multivalent vaccine. The bovine rotavirus fusion protein contains a VP6 fragment, wherein the VP6 fragment contains an amino acid sequence as represented by SEQ ID NO. 4, and at least one loop region of the following (a)˜(c) is substituted with an antigenic epitope derived from bovine coronavirus and/or an antigenic epitope derived from E. coli: (a) amino acid residues of sites 168-177, with an amino acid sequence as represented by SEQ ID NO. 1; (b) amino acid residues of sites 194-205, with an amino acid sequence as represented by SEQ ID NO. 2; and (a) amino acid residues of sites 296-316, with an amino acid sequence as represented by SEQ ID NO. 3, The bovine rotavirus fusion protein contains a plurality of antigenic epitopes, and can enable a host to generate a plurality of antibodies after immunizing the host.
    Type: Application
    Filed: April 16, 2021
    Publication date: January 6, 2022
    Inventors: Sun He, Yiping Pan, Guoqing Zhang, Pengxian Yan, Na Xi, Miaomiao Guo, Shengdong Xiao, Tianzeng Li, Rui Han, Yumeng Wang, Jiubin Du, Pei Zheng, Jian Cao
  • Publication number: 20210340509
    Abstract: The present disclosure relates to a reverse transcriptase and an application thereof. The reverse transcriptase has mutation sites such as R450H compared with the wild-type M-MLV reverse transcriptase. The reverse transcriptase has increased polymerase activity, improved thermal stability, and reduced RNase H activity.
    Type: Application
    Filed: June 25, 2021
    Publication date: November 4, 2021
    Inventors: Huanhuan Liu, Na Guo, Huizhen Li, Zhougang Zhang, Hongyan Han, Miaomiao Guo, Yue Zheng, Yuliang Dong, Wenwei Zhang, Chongjun Xu
  • Patent number: 8771620
    Abstract: Disclosed is a method for recycling lead from waste glass containing lead, which comprises the following steps: mechanical crushing waste glass containing lead, ball milling and screening to obtain glass powder containing lead; alkaline roasting the glass powder containing lead to obtain a roasted material; mixing polycarboxylic acid complexant and nitric acid to produce leaching agent, and then placing the roasted material into the leaching agent to obtain leachate; regulating pH value of the leachate to solidify metal ion to obtain precipitate, separating and removing impurities, rinsing and drying to obtain chemical product containing lead. The method avoids environment pollution caused by waste glass containing lead.
    Type: Grant
    Filed: October 27, 2010
    Date of Patent: July 8, 2014
    Assignee: Shenzhen Gem High-Tech Co., Ltd.
    Inventors: Kaihua Xu, Miaomiao Guo, Xianda He, Xiaokui Liang
  • Publication number: 20140113140
    Abstract: Provided are a coated cobalt powder and a preparation method thereof, the coated cobalt powder consisting of cobalt powder, and paraffin wax, polyethylene glycol or polyethylene coated on the outer surface of the cobalt powder. Using the coated cobalt powder to replace traditional cobalt powder as the raw material for preparing hard alloys, the dusts generated during production can be reduced, and the environment in a production shop can be improved; simultaneously, the paraffin wax, the polyethylene glycol or the polyethylene coated on the surface of the cobalt powder can effectively prevent the cobalt powder from being oxidized by the oxygen or water vapor in the air, thus improving the quality of the cobalt powder. The preparation process of the coated cobalt powder is free from contamination and the coated cobalt powder is suitable for industrialized production.
    Type: Application
    Filed: July 28, 2011
    Publication date: April 24, 2014
    Inventors: Miaomiao Guo, Zhebo Ma, Xianda He, Jifeng Zhou, Yue Fu, Cong Liu
  • Publication number: 20130129585
    Abstract: Disclosed is a method for recycling lead from waste glass containing lead, which comprises the following steps: mechanical crushing waste glass containing lead, ball milling and screening to obtain glass powder containing lead; alkaline roasting the glass powder containing lead to obtain a roasted material; mixing polycarboxylic acid complexant and nitric acid to produce leaching agent, and then placing the roasted material into the leaching agent to obtain leachate; regulating pH value of the leachate to solidify metal ion to obtain precipitate, separating and removing impurities, rinsing and drying to obtain chemical product containing lead. The method avoids environment pollution caused by waste glass containing lead.
    Type: Application
    Filed: October 27, 2010
    Publication date: May 23, 2013
    Inventors: Kaihua Xu, Miaomiao Guo, Xianda He, Xiaokui Liang