Abstract: A vehicle system includes a plurality of automated driving system electronic control units (ADS ECUs) configured to determine vehicle motion control (VMC) commands in response to input from one or more vehicle environment sensors and transmit messages including the VMC commands over one or more communication links. An execution authority electronic control unit (EA ECU) is configured with execution authority over one or more VMC commands and is configured to receive, evaluate, and execute a VMC command associated with a received message.

Abstract: This invention relates to a composition which is suitable for use in the vulcanization of the rubber. The composition is a non-aqueous water soluble polymer based composition comprising a cationic silicate component. The composition may further include a second cationic additive component which is desirable in a rubber vulcanization process. The invention further relates to a method for preparing these compositions.

Abstract: This invention relates to a composition which is suitable for use in the vulcanization of the rubber. The composition is a non-aqueous water soluble polymer based composition comprising a cationic silicate component. The composition may further include a second cationic additive component which is desirable in a rubber vulcanization process. The invention further relates to a method for preparing these compositions.

Abstract: The present invention provides for a composition which is suitable for use in the vulcanization of rubber, and a process for producing the composition. The composition comprises a salt of a vulcanization accelerator which is selected from a group of accelerator classes including thiazoles, dithiocarbamates, dithiophosphates, sulfenamides, thiuram sulfides, xanthates, guanidines, aldehyde amines, or combinations thereof; a solid particulate substrate; and a hydrophobic carrier material.

Abstract: The present invention relates to a method for the preparation of a functionalized nano size transition metal oxide or sulfide particle comprising the steps of (a) providing a ternary solvent system comprising a polar solvent, a non-polar solvent and an intermediate solvent allowing miscibility of all three components; (b) providing a mixture of a transition metal salt and a ternary solvent; (c) providing a mixture of a suitable source of oxide or sulfide and the ternary solvent; (d) providing a mixture of a non-polar end capping agent and the non-polar solvent; (e) mixing the mixtures; and (f) recovering the resultant functionalized nano size transition metal oxide or sulfide particle. The invention further relates to non-polar end capped nano sized transition metal oxide or sulfide particle so produced and the use of such particles.

Abstract: The present invention relates to rubber compositions containing a filler and comprising (i) at least one rubber containing olefinic unsaturation and (ii) functionalized nano transition metal oxide and/or sulfide particles. The invention further relates to a method of manufacture of the rubber compositions and to the use of the compositions in tires, belts and/or hoses.

Abstract: The present invention relates to a method for the preparation of a functionalized nano size transition metal oxide or sulfide particle comprising the steps of (a) providing a ternary solvent system comprising a polar solvent, a non-polar solvent and an intermediate solvent allowing miscibility of all three components; (b) providing a mixture of a transition metal salt and a ternary solvent; (c) providing a mixture of a suitable source of oxide or sulfide and the ternary solvent; (d) providing a mixture of a non-polar end capping agent and the non-polar solvent; (e) mixing the mixtures; and (f) recovering the resultant functionalized nano size transition metal oxide or sulfide particle. The invention further relates to non-polar end capped nano sized transition metal oxide or sulfide particle so produced and the use of such particles.

Abstract: The present invention relates to a rubber composition containing a filler comprising at least one rubber containing olefinic unsaturation and functionalized nano transition metal oxide and/or sulfide particles. The invention further relates to a method of manufacture the rubber compositions and to the use of such compositions in tyres, belts and/or hoses.

Abstract: The invention relates to 4-[(arylmethyl)aminomethyl]piperidine derivatives of general formula (I) in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate, and their preparation process and therapeutic application.

Abstract: The disclosure relates to a compound of formula (I): wherein R1, R2, R3, R4, R5, A and Y are as defined in the specification, to compositions containing them, to processes for preparing them, and to their use in the treatment or prevention of conditions capable of being modulated by the inhibition of the activity of protein kinases.

Abstract: The invention relates to 4-[(arylmethyl)aminomethyl]piperidine derivatives of general formula (I) in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate, and their preparation process and therapeutic application.

Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; p is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents an aromatic group selected from: the said aromatic groups being unsubstituted or being mono- or disubstituted by a substituent selected independently from a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; Preparation process and therapeutic application.

Abstract: The disclosure relates to compounds of formula (I): wherein R1-R5, A and Y are as defined in the disclosure, to compositions comprising said compounds, and to processes for making and methods of using the same.

Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4) alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents the aromatic group 1,3-thiazol-2-yl of formula: Preparation process and therapeutic application.

Abstract: The invention relates to 4-[(arylmethyl)aminomethyl]piperidine derivatives of general formula (I) in the form of a base or an addition salt with an acid, and also in the form of a hydrate or solvate, and their preparation process and therapeutic application.

Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4) alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents the aromatic group 1,3-thiazol-2-yl of formula: Preparation process and therapeutic application.

Abstract: The invention relates to substituted 1-piperazinylacylpiperidine derivatives of general formula (I) in which: n is 1 or 2; p is 1 or 2; R1 represents a halogen atom; a trifluoromethyl radical; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethoxy radical; R2 represents a hydrogen atom or a halogen atom; R3 represents a hydrogen atom; a group —OR5; a group —CH2OR5; a group —NR6R7; a group —NR8COR9; a group —NR8CONR10R11; a group —CH2NR12R13; a group —CH2NR8CONR14R15; a (C1-C4)alkoxycarbonyl; a group —CONR16R17; or else R3 constitutes a double bond between the carbon atom to which it is attached and the adjacent carbon atom of the piperidine ring; R4 represents an aromatic group selected from: the said aromatic groups being unsubstituted or being mono- or disubstituted by a substituent selected independently from a halogen atom; a (C1-C4)alkyl; a (C1-C4)alkoxy; a trifluoromethyl radical; Preparation process and therapeutic application.